Digestive System News and Research

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AI predicts health outcomes for premature newborns from blood samples

An artificial intelligence-based tool can predict the medical trajectories of individual premature newborns from blood samples collected soon after they are born, a Stanford Medicine-led study has shown.

21 Jan 2026

Gut microbiota analysis offers insights into how ultra processed foods affect health

To gain more knowledge about how ultra-processed food affects us, we need new research methods, claim researchers. Now they are looking to better understand our intestinal flora.

16 Jan 2026

Biodegradable pill improves medication adherence monitoring

In an advance that could help ensure people are taking their medication on schedule, MIT engineers have designed a pill that can report when it has been swallowed.

8 Jan 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026

How modern diets are driving rapid evolution in gut bacteria

A novel iLDS statistic uncovers adaptive gene sweeps in gut bacteria, highlighting evolutionary responses to modern diets and enhancing microbiome studies.

2 Jan 2026

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT.

23 Dec 2025

Nanoplastics alter the gut barrier and metabolism depending on diet

A team of researchers from INRAE, CNRS, and the University of Lille studied how low dietary doses of nanoplastics affected mice.

19 Dec 2025

Scorpion peppers caused him ‘crippling’ pain. Two years later, The ER bill stung him again.

Maxwell Kruzic said he was in such "crippling" stomach pain on Oct. 5, 2023, that he had to pull off the road twice as he drove himself to the emergency room at Mercy Regional Medical Center in Durango, Colorado. "It was the worst pain of my life," he said.

19 Dec 2025

Social living allows genetic effects to spread through the gut microbiome

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

18 Dec 2025

A multi-gene mouse model reveals new mechanisms of Hirschsprung disease

During development of the digestive system, a complex network of nerves forms around it, creating a "second brain" - the enteric nervous system (ENS) - which controls the movement of food and waste through the gut.

16 Dec 2025

Hidden infections may play a key role in driving long COVID symptoms

For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but a group of leading microbiologists think they may have cracked the case.

10 Dec 2025

AGA issues updated guidance for pharmacologic treatment of moderate-to-severe Crohn's disease

The American Gastroenterological Association (AGA) has released a comprehensively updated clinical guideline on the pharmacological management of moderate-to-severe Crohn's disease.

20 Nov 2025

Oral microsphere pills can detect markers of gastrointestinal disease

Move over, colonoscopies - researchers report in ACS Sensors that they've developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease.

19 Nov 2025

New review illuminates the intricate connections between gut microbiota and sleep regulation

A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.

4 Nov 2025

Discovery of vascular-associated fibroblastic cells opens new path for diabetes treatment

Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks the cells that produce insulin-a critical hormone that regulates blood sugar in the body.

8 Oct 2025

Innovative approaches target PAR2 receptor to alleviate gut pain

Abdominal pain is a hallmark of many digestive disorders, including inflammatory bowel disease and irritable bowel syndrome.

7 Oct 2025

Research highlights how the gut microbiome can affect epigenetics

The trillions of microbes that live in the human gut may play a bigger role in health than previously thought, according to a new research by the University of Hawaiʻi at Mānoa.

23 Sep 2025

Gut microbial imbalance linked to chronic sickle cell disease pain

A research collaboration involving scientists and students at The University of Texas at Dallas has found a clear connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract.

22 Sep 2025

Scientists map kissing bugs beyond the Americas to assess Chagas threat

Researchers compiled the first comprehensive dataset of 16 non-American triatomine bug species, mapping 396 verified records across Africa, Asia, and Oceania. This resource supports global Chagas disease surveillance by identifying where potential vectors are establishing new populations.

15 Sep 2025

Early diagnosis and modern therapies improve Crohn’s disease prognosis

Crohn's disease, a type of inflammatory bowel disease (IBD), impacts millions worldwide. The disease is chronic and highly unpredictable, manifesting symptoms such as abdominal pain, diarrhea — sometimes with blood — and severe fatigue.

13 Sep 2025