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New study defines rare TCF7L2-related neurodevelopmental disorder

Researchers have completed the largest study to date of TCF7L2-related neurodevelopmental disorder (TRND), a rare genetic condition caused by changes in the TCF7L2 gene, which plays an important role in brain development.

18 Sep 2026

Otolaryngologists gather to present latest advances in ear, nose, and throat care

The latest treatments and research advances in ear, nose, and throat care will take center stage in Los Angeles October 17-20, when more than 5,000 of the world's leading otolaryngologists gather for the 2026 Annual Meeting & OTO EXPO of the American Academy of Otolaryngology–Head and Neck Surgery Foundation.

18 Sep 2026

New discovery overturns a prevailing model of brain development

For centuries, scientists have thought of the brain as a single, unified organ. But new research led by Stanford Medicine reveals that what we call the brain is two distinct organs that evolved independently over hundreds of millions of years.

18 Sep 2026

Scientists discover metabolite fueling aggressive brain tumor growth

Virtually all high-grade, aggressive gliomas in adults accumulate massive amounts of a metabolite called guanidinoacetate (GAA) that overstimulates nearby neurons and promotes tumor growth, according to new research from scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cell.

18 Sep 2026

Antibody therapy teaches the immune system to control HIV

There is no cure for HIV. While scientists have made considerable progress in controlling the infection, patients still must take daily antiretroviral medication for the rest of their lives.

18 Sep 2026

Chronic stress and inflammation cause silent structural heart damage

Chronic stress from people's everyday lives may be causing lasting structural changes to the heart, harming health and reducing life expectancy.

18 Sep 2026

Ultrasound stimulation reduces deep calf muscle stiffness to prevent injuries

Muscle strain injuries are a common problem in sports, and injuries to the triceps surae, the calf muscle group that includes the gastrocnemius and soleus, can significantly affect athletic performance and return to play.

18 Sep 2026

Transplanted human cortical organoids filled most of a mouse cortex. Then they began to connect

Researchers created xenocortical mice by transplanting human cortical organoids into animals genetically depleted of much of their native cortex, allowing the human tissue to occupy most of the available cortical space and form anatomical connections throughout the host nervous system. The grafts developed diverse cortical cell types, including L5-ET and VEN-like neurons, generated organized neural activity, and produced measurable cellular and behavioral responses to hypoxic injury.

18 Sep 2026

Study identifies two opposing molecular patterns in autism models

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they converge on shared biological mechanisms?

17 Sep 2026

Sex-specific biological clocks reveal how aging differs across the body in women and men

Researchers developed 38 sex-specific biological aging clocks across 15 organ systems, finding differences between females and males in genetic architecture, molecular signatures, disease associations, and mortality patterns. Brain aging clocks were linked to progression from mild cognitive impairment to Alzheimer’s disease in both sexes and to sex-dependent cognitive trajectories among solanezumab-treated A4 participants, while the authors stressed that sex-pooled and sex-interaction models remain complementary approaches.

17 Sep 2026

Being active may not tell the whole story when it comes to weight gain

A five-year study of 2,606 young and early-midlife Finnish municipal employees examined how leisure-time physical activity and sedentary behavior were associated with gaining at least 10% of baseline body weight. About 24% of women and 12% of men experienced major weight gain, with the analysis pointing to the importance of considering activity and sedentary time together.

17 Sep 2026

Study identifies powerful inherited risk factor for lung cancer

A rare inherited mutation in the Epidermal Growth Factor Receptor (EGFR) gene is associated with a 25-fold increased risk of lung cancer, according to a study by investigators at Dana-Farber Cancer Institute and 23andMe Research Institute.

17 Sep 2026

Weill Cornell Medicine receives $17.4 million grant to shorten tuberculosis treatment

Researchers at Weill Cornell Medicine have received a $17.4 million, five-year grant from the National Institute of Allergy and Infectious Diseases to discover new approaches to shorten tuberculosis (TB) treatment, potentially making it easier for patients to complete therapy.

17 Sep 2026

Time-restricted eating may slow early-stage Huntington's disease

A simple change in when people eat may offer a promising new approach for Huntington's disease, according to research led by Oregon Health & Science University.

17 Sep 2026

New project aims to diagnose asthma in young children

Although asthma is the most common chronic condition in childhood, current tests can only diagnose it from the age of five.

17 Sep 2026

Innate immune system variations determine vaccine side effects

Redness and pain at the injection site, fever, fatigue or headaches: vaccines can cause side effects, but their frequency and severity vary considerably from person to person.

17 Sep 2026

Single-molecule imaging reveals nucleated growth mechanism of viral capsids

Oxford University researchers have captured the step-by-step assembly of individual virus-like particles, revealing how simple molecular interactions can reliably build these complex biological structures. The results have been published today (16 September) in Nature.

17 Sep 2026

Scalable machine learning model maps complex genomic enhancers across tissues

Understanding gene regulation may be the key to interpreting human disease genetics. Genes are regulated in part by stretches of DNA called enhancers, which define when, where, and how strongly each gene is turned on.

17 Sep 2026

Salk scientists demonstrate B cells directly enhance killer T cell function

Cancer is the second leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives them to innovations that revolutionize cancer care-innovations like immunotherapy.

17 Sep 2026

Genetic risk for PTSD varies across different types of trauma

A groundbreaking study reveals that your genes may make you more vulnerable to Post Traumatic Stress Disorder (PTSD) from certain types of trauma-particularly childhood neglect-than from others.

17 Sep 2026