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Understanding how base editing tools work at the molecular level

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

4 Jun 2025

Salk researchers create detailed genetic atlas of cannabis to date

Cannabis has been a globally important crop for millennia. While best known today as marijuana for its psychoactive cannabinoid THC (tetrahydrocannabinol), historically, cannabis has been a cornerstone of human civilization, providing seed oil, textiles, and food for more than 10,000 years.

29 May 2025

Scientists reveal how RNA could have replicated on early earth

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth – a key process in the origin of life.

28 May 2025

DNA strand separation requires more force in crowded cellular environments

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix undergoes before it can initiate replication or make repairs - may take more mechanical force than the field previously believed.

11 May 2025

IL-12 cytokine factory demonstrates success in targeting hard-to-treat cancers

A team of researchers from the Rice Biotech Launch Pad at Rice University has developed an implantable "cytokine factory" that safely triggers potent immune responses against hard-to-treat cancers, including metastatic melanoma, pancreatic and colorectal tumors.

8 Apr 2025

Senolytics offer hope for more precise Alzheimer's treatments

A new research paper was published in Aging (Aging-US) on March 29, 2025, as the cover of Volume 17, Issue 3, titled "Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer's disease."

1 Apr 2025

First molecular movie captures DNA unzipping at atomic level

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying their genetic material.

21 Mar 2025

Breakthrough study unveils mechanics of DNA unwinding

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life.

19 Mar 2025

Breakthrough peptide inhibitor effective against multiple SARS-CoV-2 variants

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors.

14 Mar 2025

Collagen's structural diversity may be greater than previously believed, study suggests

Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues.

7 Feb 2025

New approach combines two methods to study disordered proteins

Researchers of Mainz University and EMBL Hamburg present a new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample.

20 Jan 2025

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

Ultrasensitive ctDNA detection with NeXT Personal shows 81% sensitivity in early-stage lung adenocarcinoma, improving prognostic accuracy and therapy guidance.

15 Jan 2025

Twigstats unveils Europe’s hidden ancestral shifts from Iron Age to Viking era

Twigstats reveals ancient migrations in Europe, enhancing genomic analysis and uncovering genetic shifts from 500 BCE to 1000 CE with unprecedented precision.

3 Jan 2025

New insights into the developmental trajectory of social behaviors in fragile X syndrome

In a comprehensive Genomic Press Interview, researchers from the University of Texas Health Science Center at San Antonio and Hirosaki University have uncovered critical new insights into the developmental trajectory of social behaviors in fragile X syndrome, the leading genetic cause of autism spectrum disorder.

24 Dec 2024

Breakthrough in understanding influenza's protective coat opens path to new treatments

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of eight RNA molecules.

17 Dec 2024

Rare genetic mutations in healthy women may be key to breast cancer origins

Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early genetic origins of breast cancer - cancer-like mutations appearing in the cells of healthy women.

21 Nov 2024

Study identifies DNA collisions driving genetic changes in cancer

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

20 Nov 2024