Inflammatory Disease News and Research

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Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growth

Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable AP-1-linked chromatin changes and later amplifies tumour outgrowth after oncogenic mutation.

29 Mar 2026

Experts establish standardized protocols for pediatric recurrent wheezing diagnosis

Recurrent wheezing, a respiratory disorder, is caused by the narrowing of the airways, mainly affecting children aged less than 5 years.

26 Mar 2026

Periodontal bacteria trigger bone density reduction via the gut

Periodontitis, a chronic inflammatory disease of the gums, affects hundreds of millions of people worldwide and is increasingly linked to systemic disorders beyond the oral cavity.

4 Mar 2026

Single-cell RNA sequencing reveals accelerated T cell aging in viral infections

A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV."

19 Feb 2026

Unlocking the potential of phytochemicals in rheumatoid arthritis treatment

Announcing a new article publication for BIO Integration journal. In recent years, phytochemicals and medicinal plants have increasingly been used to treat autoimmune diseases, such as rheumatoid arthritis (RA).

16 Feb 2026

IRF7 reshapes the behavior of vascular smooth muscle cells during atherosclerosis

Atherosclerosis underlies most heart attacks and strokes and is now recognized as a chronic inflammatory disease rather than a simple disorder of cholesterol deposition.

9 Feb 2026

Research reveals a link between defective DNA repair and immune-driven inflammatory disease

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature aging and embryonic lethality in mice.

31 Jan 2026

Scientists discover a non-classical platelet mechanism linked to severe infections

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor integrin αIIbβ3. This leads to the formation of a stable platelet plug that seals the wound and stops bleeding. When this process becomes dysregulated, however, it can result in vessel-occluding clots - so-called thromboses - which may cause myocardial infarction or stroke.

23 Jan 2026

Methionine: A dietary key to surviving infection

As soon as you are wounded-whether from grabbing a hot pan or contracting the flu-you begin a unique journey through variable symptoms toward either recovery or death.

22 Jan 2026

Study shows DHPS enzyme controls macrophage maturation across multiple organs

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

21 Jan 2026

Algae may help meet future protein demand without straining the planet

This narrative review evaluates clinical evidence on algae and algal proteins as sustainable, nutrient-dense food sources with high protein quality and bioactive compounds. Findings suggest potential benefits for muscle protein synthesis, cardiometabolic markers, immune modulation, and antioxidant status, while emphasizing heterogeneity, short-term data, and the need for longer clinical trials.

20 Jan 2026

Bowel preparation for colonoscopies may temporarily alter gut balance, preclinical study suggests

New preclinical research suggests that bowel preparation procedures for colonoscopies may temporarily alter gut balance, culminating in unappreciated effects in patients with compromised gastrointestinal health.

8 Jan 2026

Experimental RNA drug shows promise for repairing DNA and healing tissue damage

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of medications that fix tissue damage caused by heart attack, inflammatory disease or other conditions.

3 Dec 2025

Asian IBD patients show lower PSC prevalence and better clinical outcomes

Primary sclerosing cholangitis (PSC) is a chronic, progressive inflammatory disease characterized by fibrosis and bile duct stricturing, which ultimately leads to cirrhosis and liver failure. PSC is strongly associated with both types of inflammatory bowel disease (IBD), namely, ulcerative colitis and Crohn's disease.

2 Dec 2025

Study reveals key role of sugars in immune cell movement during psoriasis

New research has updated our understanding of how sugars, known as glycans, help immune cells move into skin in the inflammatory disease, psoriasis.

4 Nov 2025

New evidence-based points to consider and consensus definitions for people with psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have disease that is difficult to manage (D2M) or does not respond to treatment. EULAR - The European Alliance of Associations for Rheumatology - has released new evidence-based points to consider and consensus definitions for these groups.

30 Oct 2025

Aptamer expands into targeted radiopharmaceuticals with major top 3 pharma contract

Aptamer Group plc, the developer of next-generation synthetic binders for the life sciences industry, has announced a significant development contract with a top 3 global pharmaceutical company to engineer Optimer® binders as targeted radiopharmaceuticals for potential therapeutic applications.

8 Oct 2025

GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans

The growing use of GLP-1 receptor agonists may affect the interpretation of oncological FDG PET-CT scans, new research presented today at the 38th Annual Congress of the European Association of Nuclear Medicine (EANM'25) has revealed.

7 Oct 2025

Fresh donor milk linked to reduced gastrointestinal complicatoins in premature infants

A study from the Medical University of South Carolina, published in the Journal of Parenteral and Enteral Nutrition, reveals that shorter storage durations of donor human milk are linked to reduced gastrointestinal complicatoins in premature infants, including necrotizing enterocolitis.

24 Sep 2025

Psoriasis linked to higher risk of age-related macular degeneration

New research presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2025 reveals that people with psoriasis face a significantly increased risk of developing age-related macular degeneration (AMD), a leading cause of vision loss.

17 Sep 2025