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Lupus Research Alliance launches first Translational Bridge Award to accelerate lupus treatments

The Lupus Research Alliance (LRA) is excited to announce the first-ever recipients of the Translational Bridge Award (TBA), established this year to accelerate the translation of groundbreaking research into potential treatments and diagnostics for lupus.

8 Nov 2024

Drug repurposing offers hope for SYNGAP1 patients

The SynGAP Research Fund 501(c)(3) has awarded a pair of grants to Dr. Clement Chow, a geneticist and Associate Professor in the Department of Human Genetics at the University of Utah. These grants are crucial steps in advancing therapeutic development for SYNGAP1-Related Disorders (SRD).

30 Oct 2024

Can a mushroom protein bar improve memory? Study suggests cognitive benefits of Termitomyces fuliginosus

The FCM protein snack bar, rich in amino acids and antioxidants, improves brain function and memory accuracy in just six weeks, according to recent research.

28 Oct 2024

Ground beef vs. soy-based meat: Which packs more muscle-building power?

Researchers compare the effectiveness of plant-based meat alternatives and ground beef in stimulating muscle protein synthesis.

28 Oct 2024

Human midbrain organoids: A promising tool in the fight against Parkinson's disease

Advancements in organoid technology are crucial for Parkinson's disease research, providing human-relevant models for studying disease and testing therapies.

23 Oct 2024

Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024

New consensus on assessing carcinogenic risks of gene therapies

A new article in the peer-reviewed journal Human Gene Therapy describes the consensus reached by invited experts who participated in a meeting to evaluate the potential carcinogenicity of gene therapies.

30 Aug 2024

Mediterranean diet lowers COVID-19 risk, but its effect on symptoms and severity remains uncertain

Higher adherence to the Mediterranean diet is associated with a reduced risk of COVID-19, but its effects on symptom severity are less certain due to mixed results and study limitations.

27 Aug 2024

mRNA therapy shows promise for maple syrup urine disease

Researchers from the University of Pennsylvania, Perelman School of Medicine, Gene Therapy Program, and Moderna, have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine disease (MSUD).

22 Aug 2024

High-protein diets: How they affect weight, energy, and blood sugar levels

Researchers review the effects of dietary protein on energy intake, appetite, and postprandial glycemia.

21 Aug 2024

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Research shows human cytomegalovirus (CMV) reactivation in breast milk affects milk composition, infant gut microbiome, and growth, with potential impacts on neonatal health.

28 Jul 2024

How short-term nighttime carb restriction boosts exercise and burns fat

Dietary modifications, like the sleep-low method, may improve exercise performance by optimizing glycogen storage and fat metabolism. A study in Nutrients shows night-time carbohydrate restriction benefits endurance and weight management.

10 Jul 2024

White blood cell type identified as important contributor to inflammation in obesity

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

3 Jul 2024

Regulatory T cells exist as large, mobile population that travels through body to repair damaged tissue

Researchers investigated populations of regulatory T cells, a type of white blood cell, in various tissues.

1 Jul 2024

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Study links PFAS exposure to increased cardiovascular disease risk in postmenopausal women

New research from the University of Illinois Urbana-Champaign has linked multiple types of per- and polyfluoroalkyl substances (PFAS, also known as "forever chemicals") with increased risk of cardiovascular diseases in postmenopausal women.

5 Jun 2024

New molecular analysis unravels the biological mechanisms of pediatric brain tumors

A study conducted by researchers from the D'Or Institute for Research and Education (IDOR) and the Rede D'Or Pathological Anatomy in conjunction with several North American institutions, including the National Cancer Institute (NIH), used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.

30 May 2024

Genetic link identified between inflammatory bowel disease and Parkinson's disease

The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

15 May 2024

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Study uncovers unexpected level of complexity hidden within neutrophils

In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population of short-lived immune cells.

6 Mar 2024