Lyophilization News and Research

RSS

Freeze-drying, also referred to as lyophilization, is a process that involves freezing a substance at very low temperatures and then extracting liquid via sublimation, converting water from a solid to gaseous state.

Research expands range in dry preservation of mammalian sperm cells

In a paper forthcoming in the November issue of the journal Theriogenology, a team of researchers from the University of North Carolina at Charlotte and the Smithsonian Conservation Biology Institute, announced the first successful drying and rehydration of domestic cat spermatozoa using a rapid microwave dehydration method.

12 Oct 2017

Mouse sperm subjected to cosmic environment still produces healthy offspring, report researchers

Freeze-dried mouse sperm that spent nine months in the harsh environment of space have successfully fertilized eggs and produced healthy offspring in mice.

23 May 2017

Tiny silica 'cages' could help store and transport vaccines without refrigeration

Vaccines and antibodies could be transported and stored without refrigeration by capturing them in tiny silica 'cages', a discovery which could make getting vital medicines to remote or dangerous places much easier, cheaper and safer.

24 Apr 2017

Linkam introduces new FDVS platform to replicate large scale freeze drying processes

Market leaders in temperature controlled microscopy and established manufacturers of advanced freeze drying microscopes, Linkam Scientific Instruments, announce the launch of the FDVS platform, a lyophilisation system to replicate large scale freeze drying processes.

16 Nov 2016

SP Scientific introduces powerful free software resource for freeze drying users

SP Scientific announces the introduction of the LyoModelling Calculator (LMC) - a powerful new software utility that enables those developing freeze drying cycles to calculate the time required for primary drying and the maximum product temperature based on user data input.

11 Jul 2016

Ajinomoto Althea expands biological drug product manufacturing operations

Ajinomoto Althea, Inc., a leading provider of biopharmaceutical contract development and manufacturing services, recently announced it is expanding its existing biological drug product manufacturing operations to include highly active materials such as Antibody Drug Conjugates (ADCs).

10 Dec 2015

AMRI purchases Gadea Pharmaceutical Group for $174 million

AMRI today announced that it has acquired all the outstanding shares of Gadea Pharmaceutical Group, a privately-held company located in Valladolid, Spain, specializing in technically complex active pharmaceutical ingredients (APIs) and finished drug product.

16 Jul 2015

Researchers develop mesoporous particles for use as drug delivery system

A research group led by MANA Scientist Kohsaku Kawakami, postdoctoral researcher Shaoling Zhang and MANA Principal Investigator Katsuhiko Ariga, at the International Center for Materials Nanoarchitectonics (MANA), NIMS (Sukekatsu Ushioda, President), succeeded in developing porous particles (mesoporous particles) consisting solely of phospholipids, a biological component, that are suitable for use as a drug delivery system.

10 Jun 2015

Theravectys gets authorization to produce lentiviral vectors for clinical use and CAR-T cell-based immunotherapy

THERAVECTYS, a clinical development biotechnology company that focuses on the development of therapeutic vaccines and immunotherapies, proudly announces that its manufacturing plant has obtained the status of a pharmaceutical manufacturing establishment, granted by the French National Agency for Medicines and Health Products Safety.

26 Mar 2015

Particle Sciences to expand sterile manufacturing for complex products and particulates

Particle Sciences, Inc (PSI), the leading CDMO for micro and nano-particulates is expanding its sterile and aseptic manufacturing capacity generally and specifically for nano-milled drug products.

9 Mar 2015

LSNE's Harvey Road facility receives approval to manufacture drug product for US distribution

Lyophilization Services of New England, Inc. announced today that following an FDA Pre-Approval Inspection (PAI) in November 2014, their Harvey Road manufacturing site has received approval to manufacture commercial drug product for US distribution.

7 Jan 2015

New pediatric heart-defect patches enhance electrical connections between cells

Carbon nanotubes serve as bridges that allow electrical signals to pass unhindered through new pediatric heart-defect patches invented at Rice University and Texas Children's Hospital.

24 Sep 2014

USPTO issues three new patents to Discovery Laboratories

Discovery Laboratories, Inc. (NASDAQ: DSCO), a specialty biotechnology company dedicated to advancing a new standard of respiratory critical care, today announced that the United States Patent and Trademark Office (USPTO) has issued a new patent and Notices of Allowance for patents covering critical aspects of its KL4 surfactant and drug delivery technology platform.

7 May 2014

FDA completes inspection of LSNE's medical device manufacturing facility in Manchester

Lyophilization Services of New England, a New Hampshire based contract manufacturing organization is pleased to announce that the Food and Drug Administration recently completed an inspection of their Manchester manufacturing facility.

8 Jan 2014

Habitual dietary intake of monozygotic twins associated with fecal microbiota composition

The establishment of microbial populations in the gastrointestinal-tract is a complex process, involving microbial and host interactions eventually resulting in a dense and stable population.

18 Nov 2013

FDA grants Cook Pharmica first commercial manufacturing approval

In a decision that paves the way for greater pharmaceutical industry use of the company's contract manufacturing services, Cook Pharmica LLC has received its first approval from the U.S. Food and Drug Administration (FDA) to manufacture commercial product.

18 Jun 2012

Arte, ProJect Pharmaceutics partner to develop Lyo-DCPS

Arte Corporation and ProJect Pharmaceutics have been working closely on the development of a new type of dual chamber prefillable syringe for freeze-dried pharmaceuticals. The two companies have joined together with the objective to provide innovative dual chamber syringes for the global pharmaceutical market.

6 Jun 2012

Investigators describe how they synthesized polymers to stabilize proteins

Proteins are widely used as drugs - insulin for diabetics is the best known example - and as reagents in research laboratories, but they react poorly to fluctuations in temperature and are known to degrade in storage.

22 May 2012

Soligenix first quarter revenues decrease to $647,418

Soligenix, Inc., a development stage biopharmaceutical company, announced today its financial results for the quarter ending March 31, 2012.

14 May 2012

Biological scaffold for heart valves can be freeze-dried for later use

The biological scaffold that gives structure to a heart valve after its cellular material has been removed can be freeze-dried and stored for later use as a tissue-engineered replacement valve to treat a failing heart, as described in an article in Tissue Engineering, Part C: Methods, a peer-reviewed journal from Mary Ann Liebert, Inc..

15 Feb 2012