Natural Killer Cells News and Research

RSS

Targeting lactate metabolism offers new avenues for cancer treatment

Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk.

5 Aug 2025

Common plant virus shows powerful potential as cancer immunotherapy

A virus that typically infects black-eyed peas is showing great promise as a low-cost, potent cancer immunotherapy-and researchers are uncovering why.

28 Jul 2025

Different anti-PD-L1 antibodies show varied results in tumor growth inhibition

Immune checkpoint inhibitors (ICIs), a powerful form of immunotherapy, have revolutionized cancer treatment by unleashing the body's own immune system to fight tumors.

24 Jul 2025

Structured exercise strengthens immune response in cancer treatment

Exercising during chemotherapy and before surgery may help the body send more immune cells into cancerous tumors, according to a first-of-its-kind pilot study from the University of Surrey and Royal Surrey NHS Foundation Trust.

9 Jun 2025

Combination treatment extends progression-free survival in advanced skin cancer

In patients with an advanced type of skin cancer called cutaneous squamous cell carcinoma (cSCC), those who received the combination of the immunotherapy drug avelumab and targeted agent cetuximab had almost four times longer median progression-free survival compared to patients who received avelumab alone, according to the results of a phase 2 trial presented today at the American Society of Clinical Oncology (ASCO) meeting and concurrently published in the Journal of Clinical Oncology.

1 Jun 2025

NUS researchers develop breakthrough gene delivery technology for immune cells

Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently delivers genetic material into human immune cells.

26 May 2025

Adaptive NK cells can effectively target ovarian cancer, study shows

Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumors and effectively attack them.

28 Apr 2025

Deciphering the tumor-immune interplay in endometrial carcinoma

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most prevalent gynecological cancers, EC continues to challenge researchers and clinicians due to its dynamic interaction with the immune microenvironment.

11 Mar 2025

New stem cell-based vascular grafts could revolutionize cardiac surgery

Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998.

10 Mar 2025

Modifying biomaterials may lead to more effective cancer therapies

Modifying the physical characteristics of microscopic biomaterials to interact seamlessly with the body's tissues could unlock safer and more effective cancer treatments, according to Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC.

7 Feb 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

CAR-NK cells offer safer, more accessible treatment for lymphoma

A new type of cell-based immunotherapy shows promise for B-cell lymphomas and - due to innovations in manufacturing - could make future cellular immunotherapies less expensive and more accessible to patients.

15 Jan 2025

Breakthrough microscopy technique reveals how antibodies target cancer cells

In blood cancers such as chronic lymphocytic leukaemia, B cells of the immune system multiply uncontrollably.

10 Jan 2025

Exercise prior to cancer diagnosis reduces disease progression and mortality risk

Regular physical activity before a cancer diagnosis may lower the risks of both disease progression and death, suggests research published online in the British Journal of Sports Medicine.

7 Jan 2025

Y chromosome’s unexpected impact on aging and disease in men

Loss of the Y chromosome (LOY) in men, a dynamic mutation linked to aging, impairs immune function and increases risks of cancer, Alzheimer’s, and cardiovascular diseases, making it a promising biomarker and therapeutic target.

5 Jan 2025

New approach in fighting leukemia with double-modified natural killer cells

Various forms of blood cancer exist – all of which are grouped together under the term leukemia. One common form of leukemia is acute myeloid leukemia (AML), characterized by a degradation of early blood cell precursors, i.e. stem cells and the precursor cells that develop from them.

18 Dec 2024

Study uncovers why white button mushrooms may help prevent prostate cancer progression

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, ranked among the nation's top 5 cancer centers by U.S. News & World Report and a national leader in providing cancer patients with best-in-class, integrated supportive care programs, now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined a phase 2 clinical trial studying "food as medicine."

12 Nov 2024

New light-activated technology enhances immune cells' ability to target solid tumors

Immunotherapies that mobilize a patient's own immune system to fight cancer have become a treatment pillar. These therapies, including CAR T-cell therapy, have performed well in cancers like leukemias and lymphomas, but the results have been less promising in solid tumors.

21 Oct 2024

Epigenetic testing opens new doors for multiple myeloma treatment

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population.

7 Oct 2024

Traditional Chinese medicine shows potential in cancer treatment

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, all of which have significantly contributed to improving patient survival.

1 Oct 2024