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Study finds microdosing LSD leads to longer sleep: Insights from a controlled trial

A phase I trial to assess the effect of micro-dosing of lysergic acid diethylamide (LSD) on the sleep.

17 Apr 2024

Managing diabetes with probiotics and synbiotics

Systematic review in Clinical Nutrition analyzed randomized trials to assess the impact of prebiotics and synbiotics on glycemic control in diabetes, revealing significant benefits in fasting glucose, serum insulin, and HbA1C levels.

16 Apr 2024

Study shows potential for universal flu vaccine with broad antibody response

Study discusses the potential of universal influenza vaccines, emphasizing the importance of antibody breadth and Fc receptor (FcR) effector functions in protecting against various influenza strains, including those with pandemic potential.

15 Apr 2024

Roasted green tea boosts mental task performance, study finds

Study examines how the consumption of green tea and roasted green tea affects human responses during mental tasks, demonstrating that roasted green tea can enhance performance and reduce fatigue.

15 Apr 2024

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Low-dose esketamine administered post-labor significantly reduced depressive symptoms in women with prenatal depression within 42 days, despite an increase in short-lived neuropsychiatric side effects.

14 Apr 2024

Cannabis compound d-limonene reduces anxiety-inducing effects of THC

A Johns Hopkins Medicine-led research team has added to evidence that a chemical found naturally in cannabis (also known as marijuana) can -; in the right amounts -; lessen the anxiety-inducing effects of tetrahydrocannabinol (THC), the primary psychoactive sister chemical found in cannabis.

12 Apr 2024

Low dose esketamine injection after childbirth reduces postpartum depression

A single low dose injection of esketamine given immediately after childbirth reduces major depressive episodes in individuals with depressive symptoms during pregnancy (prenatal depression), finds a clinical trial published by The BMJ today.

12 Apr 2024

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

A noninvasive brain stimulation treatment improved depression and anxiety symptoms among older adults in a new University of Florida-led study.

12 Apr 2024

New sleep-enhancing nutraceutical blend falls short in clinical trial

Study investigates the impact of a unique nutraceutical blend, combining L-theanine with valerian, saffron, and lemon balm extracts, on improving sleep quality, finding no significant difference compared to a placebo in individuals experiencing poor sleep.

10 Apr 2024

New natural supplement shows promise in preventing postpartum blues

A new study published in the Lancet discovery science journal eClinicalMedicine has confirmed that a novel natural supplement-;invented, researched, developed and commercialized at the Centre for Addiction and Mental Health (CAMH)-;prevents postpartum blues, and reduces symptoms of postpartum depression over the following six months after giving birth.

10 Apr 2024

Probiotics plus vitamin D supplements may improve cognitive function in individuals with schizophrenia

Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia.

10 Apr 2024

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

study reveals that SGLT2 inhibitors consistently lower the risk of major adverse cardiovascular events by 9% across various patient groups, especially impacting cardiovascular death reduction, highlighting their broad therapeutic potential beyond diabetes management.

9 Apr 2024

Nirmatrelvir fails to shorten COVID-19 symptoms in latest trial

A study in The New England Journal of Medicine evaluates the combination of nirmatrelvir and ritonavir against COVID-19, finding it does not significantly reduce symptom duration in vaccinated or unvaccinated adult outpatients.

8 Apr 2024

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

The investigational drug ninerafaxstat showed a good tolerability and safety profile, along with evidence of improvements in symptoms and exercise capacity among people with nonobstructive hypertrophic cardiomyopathy (HCM), according to results of a 12-week phase 2 trial presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Administering tranexamic acid (TxA), a drug used to reduce bleeding during heart surgery, topically rather than intravenously did not meet its primary endpoint of reducing seizures and was stopped early due to an increased risk of bleeding events, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment in patients who were not taking SGLT2 inhibitors or GLP-1 RAs, which are antidiabetic medications that also have benefits for the heart.

8 Apr 2024

Edetate disodium-based chelation ineffective for heart attack patients with diabetes

People with diabetes who had suffered a heart attack derived no clinical benefit from edetate disodium-based chelation, a therapy that draws lead and other toxic metals linked to increased risk of heart disease and stroke out of the body, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Lerodalcibep reduces LDL cholesterol by over 50% in high-risk patients

Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or "bad" cholesterol, levels by more than half on average, compared with a placebo.

8 Apr 2024

Novel cholesterol removal strategy shows potential benefits post-heart attack

The first trial of a novel strategy for removing cholesterol from patients' arteries did not reduce the risk of death, heart attack or stroke within three months of a prior heart attack, according to research presented at the American College of Cardiology's Annual Scientific Session. However, the findings suggest that the strategy may be beneficial with longer follow-up.

8 Apr 2024

Placebo News and Research

Study finds microdosing LSD leads to longer sleep: Insights from a controlled trial

Managing diabetes with probiotics and synbiotics

Study shows potential for universal flu vaccine with broad antibody response

Roasted green tea boosts mental task performance, study finds

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Cannabis compound d-limonene reduces anxiety-inducing effects of THC

Low dose esketamine injection after childbirth reduces postpartum depression

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

New sleep-enhancing nutraceutical blend falls short in clinical trial

New natural supplement shows promise in preventing postpartum blues

Probiotics plus vitamin D supplements may improve cognitive function in individuals with schizophrenia

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

Nirmatrelvir fails to shorten COVID-19 symptoms in latest trial

Ninerafaxstat shows good tolerability and safety in nonobstructive HCM patients

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

Edetate disodium-based chelation ineffective for heart attack patients with diabetes

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Lerodalcibep reduces LDL cholesterol by over 50% in high-risk patients

Novel cholesterol removal strategy shows potential benefits post-heart attack

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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