Proteinuria News and Research

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Proteinuria, also sometimes referred to as albuminuria or urine albumin, is a health condition characterized by an abnormal concentration of protein in the urine.

Factors shaping maternal gut microbiome during pregnancy and the impact on infant health

In an article published in the journal Current Opinion in Microbiology, scientists have provided a detailed overview of the factors affecting maternal gut microbiota during pregnancy and its impact on maternal and infant health.

17 Apr 2023

Cellular and humoral responses and the safety of recombinant and inactivated SARS-CoV-2 vaccines in chronic kidney disease patients

Researchers investigated the B cell and humoral immune responses elicited against inactivated and recombinant SARS-CoV-2 vaccines and their safety profiles in patients with CKD.

8 Feb 2023

Study examines clinical risk factors for kidney function decline in children with CKD

Chronic kidney disease (CKD) in children is rare, which makes it difficult to study and leaves major gaps in the quantity and quality of evidence that informs the care of pediatric patients with the condition.

6 Feb 2023

The role of omega-3 and omega-6 metabolites during pregnancy

Omega-3 and -6 fatty acids ingested through the diet are metabolized into bioactive compounds that influence inflammation. In a recent the journal Biomedicines study, scientists reviewed the existing literature and summarized their findings related to the role of omega-3 and omega-6 metabolites during pregnancy.

15 Jan 2023

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.

19 Oct 2022

Associations of cardioprotective medications with COVID-19 outcomes

Researchers evaluated COVID-19 outcomes in patients taking four types of cardioprotective medicines.

14 Oct 2022

RNA-dependent RNA polymerase inhibitors in COVID-19 therapy

A new paper reviews current knowledge of RdRp inhibitors that could be developed further to provide broadly effective antivirals against SARS-CoV-2 in particular and CoVs in general.

10 Oct 2022

New treatment may be effective in addressing the long-term effects of preeclampsia

Preeclampsia is a condition that affects the placenta during pregnancy and is dangerous for both the fetus and the mother.

30 Aug 2022

Adults with primary glomerular disease have high cardiovascular risk, study shows

Among almost 2,000 adults with primary glomerular disease followed for a median of 6.8 years, risk of cardiovascular events including coronary artery, cerebrovascular, and peripheral vascular events, and death due to myocardial infarction or stroke was 2.5-fold higher compared to the general population.

1 Jun 2022

Assessing the association of COVID-19 and Immunoglobulin A vasculitis in children

In a recent study posted to the Research Square* preprint server, researchers conducted a systematic review to investigate any association between immunoglobulin A (IgA) vasculitis and coronavirus disease 2019 (COVID-19) in children.

8 Feb 2022

Study evaluates the potential benefits of mass dipstick screening to detect hematuria

As the saying goes, "the sooner the better," and such is the case for the detection of kidney and urological diseases. Early detection is key, and may be achieved through the use of a dipstick urine test.

4 Feb 2022

Neutralization of SARS-CoV-2 variants by three-dose mRNA vaccinated kidney transplant recipient sera

In a new study, researchers determined three-dose messenger ribonucleic acid (mRNA) vaccinated kidney transplant recipients’ (KTRs) neutralizing responses against SARS-COV-2 variants, breakthrough coronavirus disease 2019 infection rate, and transplant rejection rate.

10 Jan 2022

Anti-rheumatic drug as a potential candidate for treating COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.

13 Oct 2021

Severe COVID-19 negatively impacts kidney function in kidney transplant recipients

During her medical school career, third-year student Skylar Nahi has taken advantage of the mentorship and research opportunities available to Feinberg students.

31 Aug 2021

COVID-19 with pre-eclampsia and acute fatty liver of pregnancy

A new study reports a case of pre-eclampsia complicated by the acute fatty liver of pregnancy (AFLP).

24 Aug 2021

Could urine tests predict kidney injury and mortality in COVID-19?

A team of scientists from the Columbia University, New York, has recently identified a potential biomarker to predict acute kidney injury in COVID-19 patients. By analyzing urine samples of 444 COVID-19 patients, they have revealed that the urinary level of neutrophil gelatinase-associated lipocalin (NGAL) can be used to determine the severity and duration of acute kidney and tubular injuries, as well as to predict the risk of mortality in acute COVID-19 patients.

15 Jun 2021

Immunomodulatory therapies for nephrological autoimmune diseases may help treat severe COVID-19

Various viruses and bacteria have long been known to cause autoimmune diseases where there is such a predisposition. This phenomenon also seems to play a major role in SARS-CoV-2, especially in severe courses.

8 Jun 2021

Study reports safety, efficacy of targeted treatment for IgA nephropathy

IgA nephropathy (IgAN) is a chronic kidney disease occurring in young adults and is one of the most common reasons for kidney transplantation in this age group.

7 Jun 2021

COVID-19 can cause long-term consequences for the kidneys

The kidneys are a target organ of COVID-19 and are affected very early in the course. However, this is precisely where there is strong prognostic potential: As early as last spring, COVID-19-associated nephritis was identified as an early warning signal for severe courses of the infectious disease and studies to that effect were published.