Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Teen cannabis use alters brain development and raises addiction risk

A systematic review reveals adolescent cannabis use alters brain structure, elevates addiction risk, and impacts cognitive outcomes during critical development.

29 Apr 2026

Bullying and social policies worsen mental health in gender-diverse teens

Gender-diverse adolescents who experience bullying and live in states with persistently unsupportive gender identity laws are significantly more likely to suffer escalating psychological distress compared to their peers, according to new research by UCLA Health.

21 Apr 2026

Your new therapist: Chatty, leaky, and hardly human

Vince Lahey of Carefree, Arizona, embraces chatbots. From Big Tech products to "shady" ones, they offer "someone that I could share more secrets with than my therapist."

17 Apr 2026

A single sauna session boosts immune cells within minutes

New research shows Finnish sauna sessions rapidly mobilize immune cells, revealing heat stress effects on cytokines and potential health benefits.

17 Apr 2026

Study finds when parents are depressed may shape children’s mental health for decades

A long-running UK cohort study found that exposure to parental depression from pregnancy through young adulthood was linked to higher odds of depression and anxiety in adult offspring. Maternal depression in late pregnancy was uniquely associated with later psychotic symptoms, while paternal associations emerged more clearly from mid-childhood onward.

14 Apr 2026

When omega-3 may help mental health and when they may not

Investigating omega-3 fatty acids, this review highlights their impact on mental health, inflammation, and the potential for therapeutic use in disorders.

10 Apr 2026

New fathers face delayed mental health risks after childbirth

Paternal mental health risks increase after childbirth, with delayed detection of psychiatric disorders underscoring the need for targeted support for fathers.

26 Mar 2026

Childhood ADHD medication shows protective effect against future psychosis

A major new study, led by scientists at University College Dublin and the University of Edinburgh and funded by the St John of God Research Foundation, has found that commonly prescribed attention deficit hyperactivity disorder (ADHD) medication in childhood may lower the long‑term risk of developing serious psychotic disorders, including schizophrenia.

25 Mar 2026

Cancer-fighting antibodies may trigger autoimmune brain disorders

Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated.

25 Mar 2026

Key gene mutation disrupts the brain’s ability to update beliefs in schizophrenia patients

One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients to struggle with making decisions and, eventually, to lose touch with reality.

18 Mar 2026

Brain waste clearance dysfunction may predict the onset of psychosis

How can we explain the onset of psychotic symptoms characteristic of schizophrenia? Despite their major and often irreversible impact on intellectual abilities and autonomy, the biological mechanisms that precede their emergence remain poorly understood.

16 Mar 2026

New digital shield against metabolic disease in youth psychosis

A new clinic-ready web-based risk prediction tool called PsyMetRiC is now available to forecast the risk of young people with psychosis developing cardiometabolic disorders such as obesity, metabolic syndrome and diabetes.

12 Mar 2026

New review calls for biologically grounded approach to psychiatric diagnosis

A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling.

10 Mar 2026

Study analyzes alterations in the cerebral cortex in people with psychosis

Researchers at the University of Seville have analyzed alterations in the cerebral cortex in people suffering from psychosis.

20 Feb 2026

How GLP-1 drugs affect the body beyond weight loss and glucose control

This review evaluates the safety profile of glucagon-like peptide-1 receptor agonists and related incretin therapies used for obesity and type 2 diabetes. It highlights common gastrointestinal effects, rare but debated risks, and areas where further long-term safety data are still needed.

18 Feb 2026

Short-duration psychedelic therapy shows promise for major depression treatment

A phase IIa randomized trial found that intravenous dimethyltryptamine (DMT) with structured psychological support produced rapid reductions in depressive symptoms in adults with major depressive disorder. Improvements were statistically significant versus placebo at two weeks, with mostly mild-to-moderate adverse events and the need for larger confirmatory studies emphasized.

17 Feb 2026

Discontinuing antidepressants during pregnancy raises psychiatric risks

Pregnant patients who stopped taking their antidepressant medication during pregnancy were almost twice as likely to experience a mental health emergency compared with pregnant patients who continued taking their prescription, according to new research presented today at the Society for Maternal-Fetal Medicine (SMFM) 2026 Pregnancy Meeting.

11 Feb 2026

Psychotic disorders increasingly diagnosed in younger Canadians

A new study suggests that people born more recently are being diagnosed with psychotic disorders (e.g., schizophrenia) more often and at younger ages compared with people born earlier.

3 Feb 2026

Study reveals rising psychosis rates among younger generations

People born more recently are being diagnosed with psychotic disorders (e.g., schizophrenia) more often and at younger ages than people born earlier, suggests a large study of more than 12 million people in Ontario, published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250926.

2 Feb 2026

King’s researchers help transform UK mental health research infrastructure

King’s researchers will help transform mental health data, clinical trials and industry partnerships as part of the UK Government’s Mental Health Goals programme.

30 Jan 2026