Sarcopenia News and Research

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Rapid zebrafish model mimics muscle aging and sarcopenia

As people age, muscles naturally lose mass and strength, a condition known as sarcopenia. The decline can make everyday activities harder and increases the risk of falls, disability and early death.

4 Feb 2026

New role for GLP-1 drugs: Improving survival in people with severe psychiatric disorders

This editorial argues that GLP-1 receptor agonists could substantially improve healthspan and reduce premature mortality in people with serious mental illnesses by targeting cardiometabolic risk rather than psychiatric symptoms alone. It highlights emerging evidence, safety considerations, and equity challenges that position GLP-1 RAs as a promising public health strategy for this high-risk population.

25 Jan 2026

Myosteatosis: An emerging predictor of outcomes in chronic liver disease

Myosteatosis, the pathological infiltration of fat into skeletal muscle, is increasingly recognized as a key predictor of poor clinical outcomes across a spectrum of liver diseases.

22 Jan 2026

NuSHs can be a promising therapeutic strategy for preventing MASH-related hepatocellular carcinoma

Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH), represent the most common chronic liver diseases in Western populations, driven largely by obesity and insulin resistance.

21 Jan 2026

Epigenetic clocks accurately predict age from human skeletal muscle

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 26, 2025, titled "Epigenetic aging signatures and age prediction in human skeletal muscle."

30 Dec 2025

Walking speed before surgery predicts who thrives after hip replacement

This study shows that preoperative gait speed is a strong predictor of patient-reported pain relief, function, and joint awareness after total hip arthroplasty for osteoarthritis. A walking speed of at least 1.0 m/s before surgery independently predicts excellent postoperative outcomes.

7 Dec 2025

Tenascin C as a key to restoring muscle regeneration in aging

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky.

5 Dec 2025

Why green tea delivers the strongest health benefits

This review examines tea's health effects, highlighting green tea's benefits for heart health and cognition, and warns about risks in processed tea products.

1 Dec 2025

New precision therapies reshape the future of pancreatitis treatment

Pancreatitis remains a major global health burden, encompassing acute pancreatitis (AP), chronic pancreatitis (CP), and autoimmune pancreatitis (AIP).

11 Nov 2025

Do dietary supplements really improve muscle health in non-athletes?

Dietary supplements can support muscle health, but their effectiveness varies. This review explores their role in physical activity and age-related muscle loss.

10 Nov 2025

Swapping meat for plant-based options cuts fat but lowers protein, study finds

Replacing meat with plant-based or mycoprotein alternatives in UK diets lowers saturated fat and boosts fiber but reduces protein intake, especially for teens and older adults. The overall saturated fat reduction is too small to meaningfully affect cholesterol levels, researchers report in npj Science of Food.

4 Nov 2025

Study provides first worldwide validation of new GLIS model in older patients with heart failure

With populations aging rapidly worldwide, heart failure has become one of the most pressing medical and social challenges.

29 Oct 2025

PAI-1 may be a promising therapeutic target for preventing age-related muscle and bone loss

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 11, 2025, titled "Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice."

23 Oct 2025

Low back pain cases in postmenopausal women doubled in 30 years

The burden of back pain in postmenopausal women has nearly doubled since 1990, driven by high BMI and metabolic health, necessitating focused health strategies.

6 Oct 2025

Calcium-induced release identified as key driver of dangerous muscle disorders

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

25 Sep 2025

Older adults reveal what makes or breaks a shift to plant-based protein

Older Dutch adults identified health and taste as the key tipping points for shifting toward protein-rich plant-based diets. Knowledge, social context, and practical tools shaped adoption, while skepticism and habits limited change.

28 Aug 2025

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

GLP-1 receptor agonists are transforming obesity and diabetes care, but may reduce skeletal muscle mass, raising concerns about sarcopenic obesity. This comprehensive review explores the mechanisms, clinical implications, and mitigation strategies, including exercise, protein intake, and adjunct therapies.

26 Aug 2025

Aston Medical School secures NIHR funding for 12 academic clinical fellows

Aston Medical School has successfully bid for funding from the National Institute for Health and Care Research (NIHR) for 12 Academic Clinical Fellows.

22 Aug 2025

New insights into how MYOD controls muscle repair and regeneration

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells.

8 Aug 2025

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

The 2024 European clinical practice guidelines introduce a pivotal terminology shift, replacing NAFLD (non-alcoholic fatty liver disease) with MASLD (metabolic dysfunction-associated steatotic liver disease) and NASH with MASH (metabolic dysfunction-associated steatohepatitis).

7 Aug 2025