Sarcopenia News and Research

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Do dietary supplements really improve muscle health in non-athletes?

Dietary supplements can support muscle health, but their effectiveness varies. This review explores their role in physical activity and age-related muscle loss.

10 Nov 2025

Swapping meat for plant-based options cuts fat but lowers protein, study finds

Replacing meat with plant-based or mycoprotein alternatives in UK diets lowers saturated fat and boosts fiber but reduces protein intake, especially for teens and older adults. The overall saturated fat reduction is too small to meaningfully affect cholesterol levels, researchers report in npj Science of Food.

4 Nov 2025

Study provides first worldwide validation of new GLIS model in older patients with heart failure

With populations aging rapidly worldwide, heart failure has become one of the most pressing medical and social challenges.

29 Oct 2025

PAI-1 may be a promising therapeutic target for preventing age-related muscle and bone loss

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 11, 2025, titled "Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice."

23 Oct 2025

Low back pain cases in postmenopausal women doubled in 30 years

The burden of back pain in postmenopausal women has nearly doubled since 1990, driven by high BMI and metabolic health, necessitating focused health strategies.

6 Oct 2025

Calcium-induced release identified as key driver of dangerous muscle disorders

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

25 Sep 2025

Older adults reveal what makes or breaks a shift to plant-based protein

Older Dutch adults identified health and taste as the key tipping points for shifting toward protein-rich plant-based diets. Knowledge, social context, and practical tools shaped adoption, while skepticism and habits limited change.

28 Aug 2025

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

GLP-1 receptor agonists are transforming obesity and diabetes care, but may reduce skeletal muscle mass, raising concerns about sarcopenic obesity. This comprehensive review explores the mechanisms, clinical implications, and mitigation strategies, including exercise, protein intake, and adjunct therapies.

26 Aug 2025

Aston Medical School secures NIHR funding for 12 academic clinical fellows

Aston Medical School has successfully bid for funding from the National Institute for Health and Care Research (NIHR) for 12 Academic Clinical Fellows.

22 Aug 2025

New insights into how MYOD controls muscle repair and regeneration

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells.

8 Aug 2025

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

The 2024 European clinical practice guidelines introduce a pivotal terminology shift, replacing NAFLD (non-alcoholic fatty liver disease) with MASLD (metabolic dysfunction-associated steatotic liver disease) and NASH with MASH (metabolic dysfunction-associated steatohepatitis).

7 Aug 2025

New blood markers predict kidney disease and mortality in diabetes

Kidney complications in diabetes often progress silently, putting patients at risk of life-threatening outcomes long before any symptoms appear. Identifying individuals with diabetes who are at risk of rapid kidney function decline or early death has challenged doctors for decades, with traditional markers like serum creatinine and urinary albumin falling short of accurately predicting these risks.

29 Jul 2025

Creatine tops the list as researchers review new ways to fight osteosarcopenia

This review explores how creatine, HMB, prebiotics, and probiotics may support muscle and bone health in older adults with osteosarcopenia. While creatine shows the strongest evidence, all interventions require further research to determine their optimal use.

21 Jul 2025

Goat milk boosts muscle health better than cow’s milk in animal study

Dairy products, especially low-fat and fortified goat milk, significantly improved muscle mass, reduced inflammation, and positively modulated gut microbiota in a mouse model of sarcopenia. These findings suggest tailored dairy interventions could help delay age-related muscle loss.

21 Jul 2025

Overuse injuries spark lasting pain and mood changes through inflammation, rat study finds

Repetitive reaching tasks in mature female rats triggered persistent pain-like and sickness behaviors linked to a surge in IL-6-driven inflammation throughout muscles, blood, and the brain. These findings reveal how overuse injuries provoke both physical and mood-related symptoms through a neuroimmune cascade.

20 Jul 2025

New tool measures how quickly muscles age to predict sarcopenia risk

A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 9, 2025, titled "Developing a quantitative estimate of muscle age acceleration by a novel phenotypic clock: cross-sectional study in healthy, middle-aged and older adults."

17 Jul 2025