Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

Pen-strep treatment rewires mechanical sensing in immune cells

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization and immune function.

13 Mar 2026

Highly biocompatible corneal implants created from recycled carp scales

Serious diseases affecting the transparent part of the eye, called the cornea, are very difficult to treat because this structure lacks blood vessels and has little capacity for regeneration and repair.

10 Mar 2026

Researchers discover protein that promotes natural dental pulp tissue regeneration

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth vitality.

10 Mar 2026

New collaboration aims to accelerate biomedical innovation and education

The Terasaki Institute for Biomedical Innovation (TIBI) and Keck Graduate Institute (KGI) have announced a new collaborative research partnership designed to accelerate biomedical innovation through joint research programs, faculty collaboration, and expanded student training opportunities.

9 Mar 2026

Targeting Wnt signaling to solve the dental pulp challenge

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a transcriptional complex with β-catenin in human dental pulp stem cells, activating Wnt signaling and promoting regenerative gene expression.

9 Mar 2026

Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis

Post-traumatic osteoarthritis often affects younger, active individuals and progresses quickly following ligament or cartilage injury.

4 Mar 2026

3D-printed scaffolds use shape memory to heal infected bone defects

Infected bone defects arise in conditions such as osteomyelitis and post-traumatic bone infections, where microbial persistence and immune imbalance prevent effective healing.

4 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Periodontal bacteria trigger bone density reduction via the gut

Periodontitis, a chronic inflammatory disease of the gums, affects hundreds of millions of people worldwide and is increasingly linked to systemic disorders beyond the oral cavity.

4 Mar 2026

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

Sepsis and severe pneumonia are frequently accompanied by disruption of the gut microbiota, leading to immune dysfunction and increased susceptibility to secondary infections.

4 Mar 2026

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

Wound healing is a multistep biological process involving inflammation, tissue formation, and remodeling.

2 Mar 2026

Reducing miRNA levels helps rescue vascular defects in Rett syndrome

MIT researchers have discovered that two common genetic mutations that cause Rett syndrome each set off a molecular chain of events that compromises the structural integrity of developing brain blood vessels, making them leaky.

25 Feb 2026

Vascularized liver tissueoid-on-a-chip recreates tissue regeneration and transplant rejection

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling the study of liver regeneration and immune-mediated allograft rejection in a physiologically relevant human system.

18 Feb 2026

Novel implant delivers tiny growth-promoting particles directly to injured nerve cells

Researchers from RCSI University of Medicine and Health Sciences have developed a novel implant that delivers tiny growth-promoting particles directly to injured nerve cells, helping them to regrow after spinal cord injury.

18 Feb 2026

Bioprinting personalized kidney tissues to combat transplant shortages

Rice University bioengineer Antonios Mikos is part of a team of researchers led by the Wake Forest Institute for Regenerative Medicine awarded up to $24.8 million over five years to help address the nation's growing organ donor shortage by bioprinting on-demand kidney tissues.

7 Feb 2026

Water pressure mechanism enables fast amoeboid cancer cell movement

Cancer is one of the leading causes of death worldwide, marked by the uncontrolled growth of abnormal cells.

7 Feb 2026

Revolutionizing 3D cell culture with simplified digital microfluidic technology

Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes.

30 Jan 2026

Engineered mesenchymal and endothelial cell layers effectively mimic native lymph nodes

The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and preventing the spread of malignancies, they sometimes come with severe long-term consequences.

23 Jan 2026

Bio-engineered skin grafts offer new hope for severe burn injuries

Bio-engineered skin grafts can play an important role in the treatment of burn victims. Researchers at the University of Zurich have been working on new approaches for such grafts for over 15 years.

15 Jan 2026

Magnetic torque boosts cardiac organoid maturation, mimicking heart development

Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is limited by the shortcomings of existing experimental models.

13 Jan 2026

Tissue Engineering News and Research

Pen-strep treatment rewires mechanical sensing in immune cells

Highly biocompatible corneal implants created from recycled carp scales

Researchers discover protein that promotes natural dental pulp tissue regeneration

New collaboration aims to accelerate biomedical innovation and education

Targeting Wnt signaling to solve the dental pulp challenge

Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis

3D-printed scaffolds use shape memory to heal infected bone defects

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Periodontal bacteria trigger bone density reduction via the gut

Gut microbiota-derived metabolite directly shapes immune responses in bacterial pneumonia

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

Reducing miRNA levels helps rescue vascular defects in Rett syndrome

Vascularized liver tissueoid-on-a-chip recreates tissue regeneration and transplant rejection

Novel implant delivers tiny growth-promoting particles directly to injured nerve cells

Bioprinting personalized kidney tissues to combat transplant shortages

Water pressure mechanism enables fast amoeboid cancer cell movement

Revolutionizing 3D cell culture with simplified digital microfluidic technology

Engineered mesenchymal and endothelial cell layers effectively mimic native lymph nodes

Bio-engineered skin grafts offer new hope for severe burn injuries

Magnetic torque boosts cardiac organoid maturation, mimicking heart development

Optimizing 3D cryopreservation using Bambanker™ eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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