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Researchers evaluate artemisinin for COVID-19 management

Researchers assessed the effectiveness of artemisinin-based antimalarials in the management of COVID-19.

16 Jun 2022

Elevated Th17 cells associated with increased risk of critical COVID

In a recent article published in the European Journal of Internal Medicine, researchers in France indicated that T cell immune reaction correlates possibly with the chance of critical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among hospitalized patients.

14 Jun 2022

Innate and adaptive immune responses to SARS-CoV-2 infection in older golden hamsters

Researchers assessed the variation in SARS-CoV-2 manifestation with age.

13 Jun 2022

People with HIV are at greater risk of breakthrough COVID-19 infections after vaccination

People with HIV have a higher rate of breakthrough COVID-19 infections after vaccination, compared to people without HIV, according to findings from a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

7 Jun 2022

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

A recent phase 1/2 study under review at the Nature Portfolio journal and posted to the Research Square* preprint server demonstrated that a peptide-centered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell activator, CoVac-1, was efficient in B-cell deficient people.

6 Jun 2022

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Researchers have discovered the mechanism by which specific immune cells can block breast cancer development and even suppress a developed tumor.

3 Jun 2022

Epidemiology and the public health response of monkeypox

Monkeypox is a zoonotic disease, i.e. it can be transmitted between animals and humans via direct or indirect contacts.

3 Jun 2022

The effects of accessory protein mutations and other non-spike mutations on SARS-CoV-2 pathogenesis

Researchers looked into the role played by the accessory proteins using synthetic genomics assembly technology

2 Jun 2022

Combination bNAb therapy may offer a future alternative to daily ART for people living with HIV

Individuals with HIV who began taking antiretroviral therapy (ART) in the early stages of infection achieved a lengthy period of HIV suppression without ART after receiving two broadly neutralizing anti-HIV antibodies (bNAbs), according to a small study published today in the journal Nature.

1 Jun 2022

Study analyzes how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2

Scientists at La Jolla Institute for Immunology have published the first analysis of how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2.

31 May 2022

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

Researchers evaluated the impact of CMV seropositivity on humoral and cellular immune responses generated after double and/or triple mRNA vaccination against SARS-CoV-2 among the elderly.

31 May 2022

New discovery could pave the way for more effective cancer immunotherapy

A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body's defenses against cancerous tumors.

31 May 2022

The immunogenicity and safety of the adjuvanted recombinant protein vaccine Sanofi/GSK-D614 or -B.1.351 administered as a heterologous booster dose

Researchers assessed the safety and immunogenicity of SARS-CoV-2 booster vaccines.

31 May 2022

Direct comparison of immune memory responses to four COVID-19 vaccines

Researchers evaluated host immune responses to four COVID-19 vaccines representing three different vaccine technology platforms, focusing on immune memory responses.

30 May 2022

Mucosal COVID vaccine candidate powerfully protective in macaques

A recent research paper posted to the bioRxiv* preprint server illustrated the protective efficacy of the intranasal pediatric parainfluenza virus-vectored coronavirus disease 2019 (COVID-19) vaccine prospect, B/HPIV3/S-6P, in macaques.

26 May 2022

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Investigators have discovered the mechanisms underlying a T-cell receptor's immunosuppressive function, according to a study published Nature Immunology, findings that may provide insight into the development of novel precision therapeutics for chronic diseases, including cancer.

25 May 2022

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

The accelerated advancement of cancer immunology and immunotherapy, a type of biological therapy that boosts the immune system's ability to recognize and kill cancer cells, has significantly improved the effectiveness of cancer treatment and patient outcomes.

25 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

In a recent study posted to the medRxiv* preprint server, investigators in Singapore showed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection elicited broadly specific virus-selective nasal resident CD8 and CD4 T cells.

24 May 2022

CD4 News and Research

Researchers evaluate artemisinin for COVID-19 management

Elevated Th17 cells associated with increased risk of critical COVID

Innate and adaptive immune responses to SARS-CoV-2 infection in older golden hamsters

People with HIV are at greater risk of breakthrough COVID-19 infections after vaccination

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Epidemiology and the public health response of monkeypox

The effects of accessory protein mutations and other non-spike mutations on SARS-CoV-2 pathogenesis

Combination bNAb therapy may offer a future alternative to daily ART for people living with HIV

Study analyzes how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

New discovery could pave the way for more effective cancer immunotherapy

The immunogenicity and safety of the adjuvanted recombinant protein vaccine Sanofi/GSK-D614 or -B.1.351 administered as a heterologous booster dose

Direct comparison of immune memory responses to four COVID-19 vaccines

Mucosal COVID vaccine candidate powerfully protective in macaques

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

New initiative aims to increase collaboration and accelerate high-impact cancer immunotherapy

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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