Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Alarming statistics from IDF reveal nearly 1 in 9 adults are now living with diabetes

Globally, nearly one in nine adults (589 million) are now living with diabetes. Of these, an estimated 252 million are not yet aware they have the condition, placing them at higher risk of serious complications and early death

4 Apr 2025

Over 250 million people worldwide unaware they have diabetes, according to new research from the International Diabetes Federation (IDF)

4 Apr 2025

Low walkability in neighborhoods associated with higher heart disease risk

Low neighborhood walkability is associated with increased risk of cardiovascular disease (CVD), according to research presented today at ESC Preventive Cardiology 2025, a scientific congress of the European Society of Cardiology (ESC).

3 Apr 2025

Heart failure linked to faster cognitive decline

There are over six million Americans with heart failure who are at greater risk of losing their cognitive abilities earlier in life, a study suggests.

3 Apr 2025

Compound heatwaves linked to increased cardiac deaths

Cardiac deaths increase significantly during compound heatwaves-heatwaves where temperatures are elevated both during the day and overnight-according to a new study in JACC, the flagship journal of the American College of Cardiology.

1 Apr 2025

NYC and Baltimore scientists awarded grants for cardiovascular and diabetes research

A New York City-based physician scientist who explores ways to improve health by looking at the ways in which cells and molecules impact disease and an epidemiologist from Baltimore who has devoted her career to identifying ways to improve screening, diagnosis and patient care for people with diabetes are the most recent American Heart Association Merit Award recipients.

1 Apr 2025

Study finds clues to hypertension hidden in electronic health records

A new study from investigators at Mass General Brigham shows that clues about hypertension may be buried in electronic health records (EHR).

1 Apr 2025

Tirzepatide improves kidney, cardiovascular function in patients with obesity and HFpEF

The drug tirzepatide improved kidney function and cardiovascular outcomes among patients with obesity and heart failure with preserved ejection fraction (HFpEF) compared with placebo at one year, according to featured clinical research presented at the American College of Cardiology's Annual Scientific Session (ACC.25) and simultaneously published in JACC.

31 Mar 2025

Fluid restriction does not improve health in heart failure patients

People with heart failure have long been advised to limit the amount of fluids they consume each day to help reduce congestion, or the buildup of fluid in the lungs and extremities, but that advice provides no benefit, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

Patients who underwent transcatheter aortic valve replacement (TAVR) with a valve designed to treat aortic regurgitation had an overall mortality rate of just 8.1% at one year, well below the trial's prespecified goal of 25% to show non-inferiority, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

$Intravenous iron shows promise for heart failure with reduced ejection fraction$

Intravenous iron shows promise for heart failure with reduced ejection fraction

Among iron-deficient patients with heart failure with reduced ejection fraction (HFrEF), receiving intravenous iron supplementation was found to be safe but resulted in mixed findings, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

Study finds no benefit of early IABP use in cardiogenic shock patients

Compared with standard medical care, early use of a temporary intra-aortic balloon pump (IABP) to support heart function in patients who were critically ill with cardiogenic shock caused by heart failure did not improve 60-day survival or enable more patients to successfully transition to long-term treatment, according to featured clinical research presented at the American College of Cardiology's Annual Scientific Session (ACC.25) and simultaneously published in JACC

31 Mar 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Investigational drug lorundrostat offers significant blood pressure drop compared with placebo

Among patients with uncontrolled hypertension, the investigational drug lorundrostat brought a significant reduction in blood pressure at 12 weeks compared with placebo, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Heart failure patients benefit from dapagliflozin after TAVR procedure

Patients with heart failure who took dapagliflozin, a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, after undergoing transcatheter aortic valve replacement (TAVR) were significantly less likely to die or experience worsening heart failure at one year compared with patients who did not take the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

WARRIOR trial finds no impact of intensive therapy on heart events in women

An intensive three-drug regimen of heart medications did not significantly impact the rate of serious cardiovascular events at five years in women who experienced signs and symptoms of ischemia, or insufficient blood flow to the heart muscle, but had no blockages in their heart's arteries, according to research presented at the American College of Cardiology's Annual Scientific Session.

29 Mar 2025

Semaglutide improves maximal walking distance in people with symptomatic PAD and Type 2 diabetes

Semaglutide, a glucagon-like peptide 1 (GLP-1) agonist, significantly improved maximal walking distance in people with symptomatic peripheral artery disease (PAD) and Type 2 diabetes in the first-of-its kind trial to evaluate the use of a GLP-1 agonist to manage PAD.

29 Mar 2025

Heart Failure News and Research

Further Reading

Alarming statistics from IDF reveal nearly 1 in 9 adults are now living with diabetes

Over 250 million people worldwide unaware they have diabetes, according to new research from the International Diabetes Federation (IDF)

Low walkability in neighborhoods associated with higher heart disease risk

Heart failure linked to faster cognitive decline

Compound heatwaves linked to increased cardiac deaths

NYC and Baltimore scientists awarded grants for cardiovascular and diabetes research

Study finds clues to hypertension hidden in electronic health records

Tirzepatide improves kidney, cardiovascular function in patients with obesity and HFpEF

Fluid restriction does not improve health in heart failure patients

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

Intravenous iron shows promise for heart failure with reduced ejection fraction

Study finds no benefit of early IABP use in cardiogenic shock patients

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

Investigational drug lorundrostat offers significant blood pressure drop compared with placebo

Heart failure patients benefit from dapagliflozin after TAVR procedure

WARRIOR trial finds no impact of intensive therapy on heart events in women

Semaglutide improves maximal walking distance in people with symptomatic PAD and Type 2 diabetes

New ESC consensus statement advances conduction system pacing therapy

Emory team takes heart disease research to the International Space Station

Machine learning identifies key comorbidities predicting premature death in IBD patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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