Hospice News and Research

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Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment.

20 Sep 2017

Sleep deprivation rapidly reduces depression symptoms in nearly half of depressed patients

Sleep deprivation -- typically administered in controlled, inpatient settings -- rapidly reduces symptoms of depression in roughly half of depression patients, according the first meta-analysis on the subject in nearly 30 years, from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Sep 2017

Penn study provides insight into how cells maintain identity during replication

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any other time.

15 Sep 2017

Research: Hospice referral at end of life should be based on older adult's pain, distressing symptoms

A team of researchers from Yale University has studied how soon older adults who were experiencing distressing symptoms and disability were admitted to hospice near the end of their lives . Their study was published in the Journal of the American Geriatrics Society.

14 Sep 2017

Modified blood thinner may be first promising method to prevent repercussions after TBI

A chemically modified version of the common blood thinner heparin may be the first promising method of preventing the harmful cascade of destruction to brain tissue that commonly follows traumatic brain injury (TBI), according to new research findings.

13 Sep 2017

Researchers estimate U.S. burden of sepsis and trends using clinical data

Sepsis, the syndrome of life-threatening organ dysfunction caused by infection, is a major cause of death, disability, and cost. Many studies suggest that the incidence of sepsis is increasing over time, while mortality rates are decreasing.

13 Sep 2017

Penn research could pave way toward new treatments for chronic sinus infections

Bitter taste receptors in the upper airway are a first line of defense against sinus infections, but their ability to kill harmful toxins and pathogens is blocked when the sweet taste receptors are also stimulated.

8 Sep 2017

Penn researcher wins National Cancer Institute Outstanding Investigator Award

M. Celeste Simon, PhD, who studies cancer cell metabolism, tumor immunology, and the influence of oxygen availability and deprivation on tumor growth, has been given a National Cancer Institute Outstanding Investigator Award.

8 Sep 2017

Retinal imaging may help doctors confirm or rule out frontotemporal degeneration

Frontotemporal degeneration (FTD) is a progressive neurodegenerative condition that is present in tens of thousands of Americans, but is often difficult to diagnose accurately.

8 Sep 2017

Detailed understanding of ‘one of the most complex organs’ could provide new ways to treat lung disorders

Details of lung cell molecular pathways that promote or inhibit tissue regeneration were reported by researchers from the Perelmen School of Medicine at the University of Pennsylvania in Cell this week. Their aim is to find new ways to treat lung disorders.

7 Sep 2017

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment.

7 Sep 2017

Researchers find correlation between shorter telomeres and presence of heart failure

Each cell in the average human body contains 23 pairs of chromosomes, with four telomeres on each pair. Telomeres cover the end of the chromosome, protecting it from deterioration or fusion with adjacent chromosomes, much like the plastic tip at the end of a shoelace protects it from unraveling.

7 Sep 2017

Shedding new light on hospice care: No need to wait for the ‘brink of death’

A few weeks ago, Kathy Brandt's 86-year-old mother was hospitalized in Florida after a fall. After rushing to her side, Brandt asked for a consult with a palliative care nurse.

7 Sep 2017

Art courses improve observational recognition skills among medical students

Observation skills are an essential component of any medical education, aiding doctors during patient exams and in making medical diagnoses, yet several studies have indicated inadequacies in this area among medical trainees and practicing physicians.

6 Sep 2017

Reduced dose of chemotherapy has no effect on overall survival of liver cancer patients

Patients with the most common type of liver cancer who are taking the chemotherapy drug sorafenib can begin their treatment with a lower dose than is currently considered standard, and it will not affect how long they live when compared to patients who start on the full dose.

6 Sep 2017

Fluorescent dye imaging tool lights up benign brain tumors during surgery

An experimental imaging tool that uses a targeted fluorescent dye successfully lit up the benign brain tumors of patients during removal surgery, allowing surgeons to identify tumor tissue, a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania shows.

6 Sep 2017

Hospice News and Research

Penn researchers identify new way to target enzyme crucial to tumor growth, develop new drugs

Sleep deprivation rapidly reduces depression symptoms in nearly half of depressed patients

Penn study provides insight into how cells maintain identity during replication

Research: Hospice referral at end of life should be based on older adult's pain, distressing symptoms

Modified blood thinner may be first promising method to prevent repercussions after TBI

Researchers estimate U.S. burden of sepsis and trends using clinical data

Penn research could pave way toward new treatments for chronic sinus infections

Penn researcher wins National Cancer Institute Outstanding Investigator Award

Retinal imaging may help doctors confirm or rule out frontotemporal degeneration

Detailed understanding of ‘one of the most complex organs’ could provide new ways to treat lung disorders

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers find correlation between shorter telomeres and presence of heart failure

Shedding new light on hospice care: No need to wait for the ‘brink of death’

Art courses improve observational recognition skills among medical students

Reduced dose of chemotherapy has no effect on overall survival of liver cancer patients

Fluorescent dye imaging tool lights up benign brain tumors during surgery

Special program enables nurses to better prepare for providing palliative care

Researchers identify gene variants linked to both type 2 diabetes and CHD risk

Review: Palliative care makes progress only in small subset of countries in Africa

Comprehensive program takes patient care to next level by improving lives of women with ovarian cancer

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The role of UV-Vis in biopharma QC

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