Immune Response News and Research

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Study links COVID-19 infection to accelerated blood vessel aging in women

A Covid infection, particularly in women, may lead to blood vessels aging around five years, according to research published in the European Heart Journal on 18th August, 2025.

18 Aug 2025

Stem-like peripheral helper T cells found to sustain inflammation in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives.

17 Aug 2025

Gut neurons drive immune responses through adrenomedullin 2

Neurons in the gut produce a molecule that plays a pivotal role in shaping the gut's immune response during and after inflammation, according to a new study by Weill Cornell Medicine investigators.

17 Aug 2025

Genetically-engineered immune cells show promise for preventing organ rejection

A Medical University of South Carolina team reports in Frontiers in Immunology that it has engineered a new type of genetically modified immune cell that can precisely target and neutralize antibody-producing cells complicit in organ rejection.

17 Aug 2025

Engineered CD40 antibody shrinks tumors and induces remission

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise-and induced great disappointment.

14 Aug 2025

Pandemic left measurable changes in teen brains, hormones, and immunity

Adolescents assessed after COVID-19 lockdowns showed lower daily cortisol, higher inflammation, and reduced prefrontal cortex activity compared to matched pre-pandemic peers, suggesting widespread stress-related biological changes. These alterations mirror patterns seen after prolonged early-life stress, raising concerns about long-term health risks.

13 Aug 2025

mRNA vaccine shows potent efficacy in gastric cancer

Gastric cancer is one of the leading causes of cancer-related mortality worldwide, and peritoneal metastasis, wherein the cancer spreads to the peritoneum or the lining of the abdominal cavity, represents the most common form of recurrence after gastric cancer surgery.

13 Aug 2025

Old Parkinson's medication offers new hope for tuberculosis treatment

A medication developed in the 1950s to treat Parkinson's disease may offer a powerful new tool in the fight against tuberculosis (TB), according to new research from the University of British Columbia.

12 Aug 2025

Adding MET inhibitor enhances immune response against small cell lung tumors

Adding a MET gene inhibitor enhances the effect of combined chemotherapy and immunotherapy in small cell lung cancer (SCLC), according to a multicenter study led by the Hospital del Mar Research Institute, in collaboration with researchers from the CIBERONC cancer research network.

12 Aug 2025

Researchers develop machine learning models to identify biomarkers for chronic fatigue syndrome

When cells expire, they leave behind an activity log of sorts: RNA expelled into blood plasma that reveal changes in gene expression, cellular signaling, tissue injury and other biological processes.

11 Aug 2025

Early clinical trial supports MASL as a targeted oral cancer treatment

Rowan University and Sentrimed, a clinical-stage biopharmaceutical company focused on developing safer, orally dosed oncology therapies, today announced results from a National Cancer Institute (NCI) funded clinical trial evaluating MASL in patients with oral squamous cell carcinoma (OSCC).

8 Aug 2025

Decoding macrophage immune responses with gene editing and machine learning

Fighting off pathogens is a tour de force that must happen with speed and precision. A team of researchers at CeMM and MedUni Vienna led by Christoph Bock and Matthias Farlik has investigated how macrophages-immune cells that are the body's first responders-master this challenge.

8 Aug 2025

New insights into how SETD2 shapes immunity and disease

The emerging role of SETD2 in regulating immune cell function is shedding light on potential therapeutic strategies for a range of immune-related diseases.

7 Aug 2025

Understanding sex-based differences in immune system function

Many diseases affect men and women differently. Asthma tends to strike men earlier in life, yet more women develop asthma as they get older.

7 Aug 2025

Breakthrough in nanoparticle technology could expand access to biologic medicines

In a discovery that could broaden access to next-generation biologic medicines and vaccines, researchers at the University of Chicago Pritzker School of Molecular Engineering (UChicago PME) have engineered polymer-based nanoparticles that form with a simple temperature shift-no harsh chemicals, no specialized equipment, and no processing needed.

7 Aug 2025

Nanoparticles could slow rheumatoid arthritis progression and reduce flare severity

As a chronic condition, rheumatoid arthritis (RA) can't be cured, so treatment focuses on managing the disease and controlling its progression. Although current treatments help control RA symptoms in most people, they cannot prevent the onset of RA or painful flare-ups.

6 Aug 2025

Study uncovers inflammatory pathways that contribute to asthma flare-ups in children

A recent multicenter clinical trial has uncovered inflammatory pathways that contribute to asthma flare-ups in children that occur despite treatment, according to findings published in JAMA Pediatrics.

1 Aug 2025

New approach preserves insulin-producing cells in diabetes model

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team.

1 Aug 2025

Artificial sweetener may undermine effectiveness of cancer treatment

Sucralose is a popular sugar substitute for people who are cutting calories or managing blood sugar levels, but new research by the University of Pittsburgh and UPMC Hillman Cancer Center suggests that the artificial sweetener may not be the best choice for patients undergoing cancer immunotherapy.

31 Jul 2025