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Actin influences cancer metastases in many ways

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues.

31 Jan 2023

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

A new study discusses the impact of several human viruses on blood-brain barrier function and insulin sensitivity.

31 Jan 2023

Data demonstrates SARS-CoV-2 Omicron XBB.1.5 substantially escapes NAb responses after bivalent mRNA boosting

Researchers reported that the SARS-CoV-2 Omicron XBB.1.5 variant evades neutralizing response elicited by bivalent vaccine boosters.

25 Jan 2023

Study reveals how neural networks play a key role in the regulation of circadian rhythms

Circadian rhythms are inherent cycles of approximately 24 hours that regulate various biological processes, such as sleep and wakefulness.

19 Jan 2023

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

Researchers explored ways galectins can impact immunity and discussed the opportunities and challenges in the field.

18 Jan 2023

S. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein A

Researchers assessed the impact of Staphylococcus aureus (S. aureus) on SARS-CoV-2 replication.

17 Jan 2023

How salt appetite differs between males and females

A recent Nutrients study reviews differences in salt intake based on sex.

16 Jan 2023

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

Researchers investigated how age-related T-cell defects impacted the effectiveness of mRNA-based COVID-19 vaccines.

16 Jan 2023

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Neurodegenerative diseases affect millions of people worldwide and as our life expectancy increases, more individuals are expected to be affected in the coming decades.

16 Jan 2023

Targeting T cell iron metabolism may offer a new approach for treating lupus

Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) - the most common form of the chronic autoimmune disease lupus.

13 Jan 2023

Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants

In a recent study posted to bioRxiv*, researchers designed a nanoparticle (NP)-conjugated toll-like receptor 9 (TLR9) agonist to improve the adjuvanticity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

8 Jan 2023

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a "morning after" nasal spray that could knock out respiratory viruses' ability to colonize your nose and throat.

5 Jan 2023

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

Dietary supplement can reverse the signs of heart disease in a subset of patients

When we were little, our parents told us to take our vitamins so we could grow big and strong. Now, researchers from Japan find that one particular supplement may even fix a broken heart.

4 Jan 2023

Underlying genetic cause for MIS-C complications after COVID-19 identified

A recent Science journal study determined the underlying cause of MIS-C related to SARS-CoV-2 in some children. It hypothesized that monogenic inborn errors of immunity (IEI) is the primary reason for this condition. Identifying these inborn errors is expected to help elucidate the disease's cellular, molecular, and immunological basis.

2 Jan 2023

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies."

29 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Researchers described a messenger ribonucleic acid (mRNA)-lipid nanoparticle monkeypox vaccine encoding four conserved monkeypox virus surface proteins which induced monkeypox virus-specific immunity and elicited heterologous protection when challenged with lethal vaccinia virus.

23 Dec 2022

Cellular models based on reprogrammed human cells could boost development of efficient therapies

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies.

22 Dec 2022

Intracellular News and Research

Actin influences cancer metastases in many ways

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

Data demonstrates SARS-CoV-2 Omicron XBB.1.5 substantially escapes NAb responses after bivalent mRNA boosting

Study reveals how neural networks play a key role in the regulation of circadian rhythms

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

S. aureus enhances replication of SARS-CoV-2 in vitro through the bacterial iron-regulated surface determinant protein A

How salt appetite differs between males and females

The trajectory of CD4+ T cell responses to mRNA vaccines in older individuals

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Targeting T cell iron metabolism may offer a new approach for treating lupus

Researchers review bacteriophage treatment

COVID-19 vaccine potency and breadth improved by nanoparticle-conjugated adjuvants

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Dietary supplement can reverse the signs of heart disease in a subset of patients

Underlying genetic cause for MIS-C complications after COVID-19 identified

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Novel mRNA-lipid nanoparticle vaccine encoding four mpox virus surface proteins generates robust immune responses against orthopoxviruses

Cellular models based on reprogrammed human cells could boost development of efficient therapies

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