Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

What the air you breathe may be doing to your brain

For years, the two patients had come to the Penn Memory Center at the University of Pennsylvania, where doctors and researchers follow people with cognitive impairment as they age, as well as a group with normal cognition.

12 Nov 2025

Midlife blood test may reveal Alzheimer’s disease risk in advance

A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer's disease decades ahead of time, allowing for possible preventive therapy.

11 Nov 2025

Scientists pinpoint a reason Alzheimer’s patients forget loved ones

One of the most devastating moments for family members of a patient with Alzheimer's is when their loved one forgets who they are. New University of Virginia School of Medicine research may explain why that happens and could lead to a way to prevent it.

10 Nov 2025

Study provides insights into the obesity–breast cancer link

Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood.

10 Nov 2025

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

A new radioimmunotherapy approach has the potential to cure human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to new research published in the November issue of The Journal of Nuclear Medicine.

7 Nov 2025

Comprehensive kinase atlas reveals new insights into cell signaling and disease

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

Inflammation identified as a key driver in the earliest stages of lung cancer

By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The University of Texas MD Anderson Cancer Center have discovered that the earliest stages of lung cancer may be driven by inflammation, suggesting that targeting proinflammatory pathways could be an early intervention approach.

6 Nov 2025

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

Lowering the transcription factor PU.1 reprograms microglia into a neuroprotective, lymphoid-like state that compacts amyloid, blocks tau spread, and preserves synapses in Alzheimer’s disease. Microglial CD28 signaling helps restrain inflammation, revealing a regulatory switch that may inform future immunotherapies targeting microglia rather than neurons.

6 Nov 2025

AI and protein language models can accelerate the design of antiviral antibodies

Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study led by researchers at Vanderbilt University Medical Center.

5 Nov 2025

Newly identified microglia subtype offers protection against Alzheimer’s disease

In Alzheimer's disease, the leading cause of dementia, microglia-the brain's immune defenders-can act as both protectors and aggressors, shaping how the disease progresses.

5 Nov 2025

Inhibiting ferroptosis suppressor protein 1 shrinks lung cancers in mice

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

5 Nov 2025

Free radicals generated at a specific site in astrocytes may promote dementia

Researchers have discovered that free radicals generated at a specific site in non-neuronal brain cells called astrocytes, may promote dementia, according to a Weill Cornell Medicine study.

4 Nov 2025

Small increases in daily steps may slow Alzheimer’s progression

Increasing your steps by even a little bit may help slow down the progression of Alzheimer's disease among people at heightened risk, according to a new study.

3 Nov 2025

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Acute myeloid leukemia driven by tandem duplications within the UBTF gene (UBTF-TD AML) is a high-risk pediatric cancer in urgent need of novel therapeutic options.

3 Nov 2025

Genetic insights into vestibular system damage from ototoxic drugs

The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, leading to alterations in balance and other motor skills.

31 Oct 2025

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.

31 Oct 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

Pathology News and Research

Further Reading

What the air you breathe may be doing to your brain

Midlife blood test may reveal Alzheimer’s disease risk in advance

Scientists pinpoint a reason Alzheimer’s patients forget loved ones

Study provides insights into the obesity–breast cancer link

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

Comprehensive kinase atlas reveals new insights into cell signaling and disease

Inflammation identified as a key driver in the earliest stages of lung cancer

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

AI and protein language models can accelerate the design of antiviral antibodies

Newly identified microglia subtype offers protection against Alzheimer’s disease

Inhibiting ferroptosis suppressor protein 1 shrinks lung cancers in mice

Free radicals generated at a specific site in astrocytes may promote dementia

Small increases in daily steps may slow Alzheimer’s progression

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Genetic insights into vestibular system damage from ototoxic drugs

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

Study finds more commonalities between CTE and Alzheimer's disease at the genetic level

Some hormonal contraceptives linked to higher risk of breast cancer

Research identifies biomarkers in blood to fine-tune breast cancer interventions

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