Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Research investigates whether the severity of SARS-CoV-2 infection can be predicted by analyzing the immunophenotype in the blood of cardiovascular disease (CVD) patients.

1 May 2023

Opening doors for broader participation in oral microbiome studies: the stability and comparability of ethanol-free mouthwash

Researchers compared the use of ethanol-free and ethanol-containing mouthwash for oral microbiome studies.

1 May 2023

Reducing COVID-19 burden: could Bacille Calmette-Guérin (BCG) vaccines confer protection?

Researchers investigated whether BCG vaccines could lower COVID-19 burden.

1 May 2023

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Scientists discuss hantavirus infections, which are a type of viral hemorrhagic fever that can be transmitted to humans through exposure to infected rodents in endemic areas.

30 Apr 2023

A study surveilling Vermont wildlife detects no SARS-CoV-2

The surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in wildlife in Vermont, United States (US).

28 Apr 2023

The BCG vaccine does not decrease the risk of COVID-19 in healthcare workers

Researchers evaluated whether the BCG vaccine could protect healthcare workers against coronavirus disease 2019.

28 Apr 2023

NVX-CoV2373 COVID vaccine safe and effective in preventing COVID-19 in adolescent

Research reports the results of a phase 3 clinical trial evaluating the safety, immunogenicity, and efficacy of the NVX-CoV2373 vaccine in adolescents aged 12 to 17 years. The study found that the vaccine was safe, immunogenic, and efficacious in preventing COVID-19, including the Delta variant, in adolescents.

27 Apr 2023

What is the risk for symptomatic H5N1 virus infection in humans?

Researchers from the CDC reported on the recent outbreak of the highly pathogenic avian influenza (HPAI) virus among domesticated and wild birds in 39 U.S. states and discussed the potential risks to humans.

27 Apr 2023

Study suggests the zoonotic-like avian H3N8 virus has limited efficiency for human-to-human transmission and is unlikely to cause severe disease in humans

Researchers demonstrated that the novel and avian hemagglutinin 3 neuraminidase 8 (H3N8) virus showed limited replication in explant cultures of lung and bronchial tissue.

27 Apr 2023

Smoking alters lung microbiome, leading to loss of diversity and community structure

Research investigates the impact of smoking on the lower respiratory tract microbiome. The study found that smoking results in a loss of diversity in the microbiome, changes in co-occurrence patterns, and a weakening of the tight community structure present in healthy microbiomes.

26 Apr 2023

The epidemiology of SARS-CoV-2 in white-tailed deer

Researchers explored the epidemiological factors of SARS-CoV-2 in white-tailed deer.

26 Apr 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Researchers documented surveillance across a network of 155 acute care hospitals in Canada between March 15, 2020, and May 28, 2022.

24 Apr 2023

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Researchers detected a cryptic severe acute respiratory syndrome coronavirus 2 lineage on mink farms in Poland.

24 Apr 2023

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Polymerase Chain Reaction News and Research

Further Reading

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Opening doors for broader participation in oral microbiome studies: the stability and comparability of ethanol-free mouthwash

Reducing COVID-19 burden: could Bacille Calmette-Guérin (BCG) vaccines confer protection?

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

A study surveilling Vermont wildlife detects no SARS-CoV-2

The BCG vaccine does not decrease the risk of COVID-19 in healthcare workers

NVX-CoV2373 COVID vaccine safe and effective in preventing COVID-19 in adolescent

What is the risk for symptomatic H5N1 virus infection in humans?

Study suggests the zoonotic-like avian H3N8 virus has limited efficiency for human-to-human transmission and is unlikely to cause severe disease in humans

Smoking alters lung microbiome, leading to loss of diversity and community structure

The epidemiology of SARS-CoV-2 in white-tailed deer

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

What are the trends in severe outcomes among patients hospitalized with COVID-19 during the first 2 years of the COVID-19 pandemic?

Study identifies an unknown SARS-CoV-2 lineage on three mink farms in Poland

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Can SARS-CoV-2 infection cause diabetes?

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Is there an association between exposure to ultrafine particles during pregnancy and influenza infection severity?

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo