Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

Cleveland Clinic researcher awarded $2.6 million grant to create innovative models of colorectal cancer

Cleveland Clinic researcher Emina Huang, M.D., a colorectal surgeon in the Digestive Disease and Surgery Institute and a staff member in the Lerner Research Institute's Department of Stem Cell Biology and Regenerative Medicine, has been awarded a collaborative five-year, $2.6 million grant from the National Cancer Institute to create innovative models of colorectal cancer that will enhance understanding of how the disease develops and spreads.

31 Oct 2017

Nanodiamonds could prevent infection, improve recovery after root canal treatment

People who undergo root canals may soon have a tiny but powerful ally that could prevent infection after treatment.

24 Oct 2017

Penn State researcher creates step-index optical fiber for light delivery inside the body

A flexible, biodegradable optical fiber that can deliver light into the body for medical applications is the latest work of a collaboration between electrical engineers and biomaterials engineers in Penn State's Materials Research Institute.

11 Oct 2017

Researchers develop new diagnostic and prognosis method for early detection of liver cancer

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.

9 Oct 2017

Tissue engineering methods could prove useful to create cartilage implants

Different surface topographies and materials provide interesting ways to study cell behaviour and potentially provide novel solutions for treating joint defects. Tissue engineering methods that simulate native cartilage could prove useful to create cartilage implants in the laboratory, according to a doctoral dissertation from Umeå University.

22 Sep 2017

New drug treatment linked to higher bladder compliance after spinal cord injury

Researchers have shown that compared to placebo, a drug treatment intended to prevent remodeling of the bladder wall and given within 48 hours after spinal cord injury (SCI) in dogs was associated with significantly higher bladder compliance.

7 Sep 2017

CSHLP releases new book on Tissue Engineering and Regenerative Medicine

Cold Spring Harbor Laboratory Press announced the release of Tissue Engineering and Regenerative Medicine, available on its website in hardcover, paperback, and ebook formats.

6 Sep 2017

New review explores evolving treatments and future therapies for osteoarthritis pain

A new review by David A. Walsh and Joanne Stocks in the September 2017 issue of SLAS Discovery (formerly the Journal of Biomolecular Screening) explores evolving treatments and future therapies for osteoarthritis (OA) pain.

26 Aug 2017

Researchers compare effectiveness of natural and synthetic materials for dental pulp tissue engineering

To regenerate dental pulp tissue after emptying of a tooth's root canals researchers compared the effectiveness of 3D scaffolds made of natural or customized synthetic materials containing pulpal stem cells and dentin-derived growth factors.

23 Aug 2017

Gravity, mechanical loading play critical role during cartilage development, study shows

Mechanical loading, or forces that stimulate cellular growth for development, is required for creating cartilage that is then turned to bone; however, little is known about cartilage development in the absence of gravity or mechanical loads.

22 Aug 2017

Researchers examine suitability of silk protein for production of cardiac tissue

Ever more people are suffering from cardiac insufficiency, despite significant advances in preventing and minimising damage to the heart.

18 Aug 2017

ICP monitoring does not improve favorable outcome rate in patients with severe TBI, study shows

A new study has shown that use of intracranial pressure (ICP) monitoring in patients with severe traumatic brain injury (TBI) was associated with a significant decrease in mortality, but it did not improve the rate of favorable outcomes.

16 Aug 2017

Scientists aim to find out how lung cells react in space

Space travel can cause a lot of stress on the human body as the change in gravity, radiation and other factors creates a hostile environment.

14 Aug 2017

Bioactive 'tissue papers' show potential for regenerative medicine

Northwestern Medicine scientists and engineers have invented a range of bioactive "tissue papers" made of materials derived from organs that are thin and flexible enough to even fold into an origami bird.

7 Aug 2017

3D-printed models help shorten surgery time for common hip disorder in children

A team of engineers and pediatric orthopedic surgeons are using 3D printing to help train surgeons and shorten surgeries for the most common hip disorder found in children ages 9 to 16.

2 Aug 2017

Researchers compare bone-healing effects of three low-dose growth factors

Researchers compared the effects of three bone growth factors to bone morphogenetic protein 2 (BMP2) -- the most commonly used agent for repair of large bone defects, which is not without risks at the doses required--and showed significant bone-healing effects including the formation of new blood vessels at low doses relative to BMP2.

28 Jul 2017

Hydrogel-based capsules may help patients adhere to medications

Around half of all medications for chronic diseases are not taken as prescribed, costing the U.S. health care system more than $100 billion in avoidable hospital stays each year.

25 Jul 2017

Researcher models heart attack in petri dishes to gain insights into cardiac diseases

In petri dishes in her campus laboratory at New Jersey Institute of Technology, Alice Lee is developing colonies of cardiac cells, formed into chambers, that pump and contract like a human heart.

18 Jul 2017

Cambridge scientists develop new method for growing and transplanting artificial bile ducts

Cambridge scientists have developed a new method for growing and transplanting artificial bile ducts that could in future be used to help treat liver disease in children, reducing the need for liver transplantation.

3 Jul 2017

Researchers develop new biocompatible materials for soft-tissue adhesion

Researchers at Okayama University describe in Acta Biomaterialia a new type of biocompatible adhesive material. The adhesive, made from nanoparticles of hydroxyapatite, glues both synthetic hydrogels and mouse soft tissue, providing a promising alternative to organic materials currently in use for clinical applications.

30 Jun 2017