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Researchers link 9 blood proteins to breast cancer and suggest 3 drugs for repurposing

Researchers link 9 blood proteins to breast cancer and suggest 3 drugs for repurposing

Researchers used integrated Mendelian randomization in a cohort of over 247,000 individuals to identify 62 plasma proteins associated with breast cancer risk. Nine high-confidence targets, including ULK3 and CSK, showed potential for drug repurposing and immune pathway regulation.

16 Apr 2025

New hope for sclerosteosis patients through Wnt pathway inhibition

New hope for sclerosteosis patients through Wnt pathway inhibition

Sclerosteosis arises from mutations in the SOST gene, causing abnormally high bone mass and skeletal overgrowth, which can lead to severe health issues such as hearing loss and increased intracranial pressure.

16 Apr 2025

What sauerkraut can do for your gut

What sauerkraut can do for your gut

Fermented cabbage metabolites play a crucial role in maintaining gut barrier function, suggesting potential health benefits for inflammatory disorders.

16 Apr 2025

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced it has signed an exclusive distribution agreement with MineBio, a leading Chinese supply chain and logistics organization

From Atelerix Ltd 16 Apr 2025

Study reveals a potential breakthrough in treating osteonecrosis of the femoral head

Study reveals a potential breakthrough in treating osteonecrosis of the femoral head

A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse.

15 Apr 2025

Study identifies a new key factor contributing to aggressive nature of pancreatic cancer

Study identifies a new key factor contributing to aggressive nature of pancreatic cancer

Pancreatic cancer is one of the most aggressive cancers and has one of the lowest survival rates-only 10% after five years.

15 Apr 2025

Selective depletion of PD-1 positive lymphocytes using a novel bispecific killer engager

Selective depletion of PD-1 positive lymphocytes using a novel bispecific killer engager

This new article publication from Acta Pharmaceutica Sinica B, discusses a bispecific killer engager for targeted depletion of PD-1 positive lymphocytes.

14 Apr 2025

New assay detects epigenetic changes caused by carcinogenic chemicals

New assay detects epigenetic changes caused by carcinogenic chemicals

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard.

10 Apr 2025

Researchers explore drug repurposing strategy for Parkinson's disease

Researchers explore drug repurposing strategy for Parkinson's disease

Despite significant advances in Parkinson's disease (PD) treatment, it remains incurable, with limited therapeutic options.

10 Apr 2025

Smaller hatching embryos more likely to be genetically healthy

Smaller hatching embryos more likely to be genetically healthy

A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 5, 2025, titled "Reproductive aging, preimplantation genetic testing for aneuploidy, and the diameter of blastocysts: does size matter?"

9 Apr 2025

Dynamic BH3 profiling offers personalized lung cancer therapies

Dynamic BH3 profiling offers personalized lung cancer therapies

Eighty-five percent of diagnosed cases of lung cancer are non-small cell lung cancer (NSCLC). In this group, 5% of patients show molecular alterations in the ALK gene involved in cell multiplication.

9 Apr 2025

Study links food additive mixtures to increased risk of type 2 diabetes

Study links food additive mixtures to increased risk of type 2 diabetes

Food additive mixtures are an everyday feature of our diets, especially through ultra-processed foods.

9 Apr 2025

Lack of ceramides in blood vessels could lead to obesity-related heart diseases

Lack of ceramides in blood vessels could lead to obesity-related heart diseases

New research from Weill Cornell Medicine has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes-not the presence of certain fats, but their suppression.

8 Apr 2025

High-fat diet fuels cancer spread via rogue platelets

High-fat diet fuels cancer spread via rogue platelets

Researchers explore the role of a high-fat diet in promoting the formation of premetastatic niches and platelet activation.

7 Apr 2025

Tecan expands portfolio for specialty diagnostics with an asset purchase relating to certain ELISA kits

Tecan expands portfolio for specialty diagnostics with an asset purchase relating to certain ELISA kits

Tecan Group today announced an agreement to acquire certain assets relating to key ELISA immunoassay products from Cisbio Bioassays SAS, a subsidiary of the global life sciences and diagnostics company, Revvity Inc.

7 Apr 2025

Key cellular mechanism affecting the function of mRNA vaccines revealed

Key cellular mechanism affecting the function of mRNA vaccines revealed

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics.

3 Apr 2025

Drug-carrying DNA aptamers offer dual action against leukemia stem cells

Drug-carrying DNA aptamers offer dual action against leukemia stem cells

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

3 Apr 2025

Study links neurotensin deficiency to ovulatory dysfunction in PCOS

Study links neurotensin deficiency to ovulatory dysfunction in PCOS

Polycystic ovary syndrome (PCOS) represents a significant health concern for women of reproductive age, manifesting as a complex endocrine disorder with diverse clinical presentations.

3 Apr 2025

Exploring drug absorption models through particle size, dose, and confinement

Exploring drug absorption models through particle size, dose, and confinement

Learn how particle size, dose, and confinement parameters advance drug absorption modeling.

From Pion Inc 3 Apr 2025

Unraveling resistance to CDK4/6 inhibitors in ovarian cancer

Unraveling resistance to CDK4/6 inhibitors in ovarian cancer

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies.

3 Apr 2025

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