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Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Crown Bioscience, a global contract research organization (CRO) and JSR Life Sciences company, today announced the launch of its ground-breaking service offering, OrganoidXploreTM.

13 Nov 2023

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

In this study, researchers harnessed crowdsourcing and open science to develop new antivirals against SARS-CoV-2, focusing on its main protease, Mpro. Their approach led to the discovery of potent compounds, including one with high efficacy in cell lines and cross-reactivity against various COVID-19 variants, demonstrating the potential of collaborative and transparent drug discovery in tackling global health crises.

12 Nov 2023

Researchers identify key factors involved in DNA repair mechanism

Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies.

12 Nov 2023

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

A recent study in the journal BMC Medicine evaluates the real-world impact of combining antidepressants with statins in UK adults, revealing lower discontinuation rates but similar efficacy compared to antidepressant-only treatment.

12 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Lowering sodium intake can help reduce blood pressure

Nearly everyone can lower their blood pressure, even people currently on blood pressure-reducing drugs, by lowering their sodium intake, reports a new study from Northwestern Medicine, Vanderbilt University Medical Center and the University of Alabama at Birmingham.

11 Nov 2023

US reporting system to detect vaccine safety issues may not be meeting its own standards

A US reporting system designed to detect potential safety issues with vaccines is supposed to be user-friendly, responsive, and transparent.

10 Nov 2023

CÚRAM researchers make breakthrough in cell visualization

CÚRAM researchers at University of Galway, together with colleagues at the Centre for Molecular Nanometrology at University of Strathclyde have published work unveiling the inner workings of cells.

10 Nov 2023

Genetically engineered yeast cells produce natural plant product for schizophrenia treatment

An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

10 Nov 2023

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Andrew Buchanan on the Future of Biologics and AI

10 Nov 2023

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Mark Abbott, the Managing Director of Peak Proteins, about protein science and its significance in drug discovery.

10 Nov 2023

Developing a synthetic pathology framework: A step towards replacing animal testing

Researchers establish AnimalGAN as a reliable alternative for generating synthetic pathology data.

10 Nov 2023

WHO experts update guidance on COVID-19 treatments

A panel of international experts representing the World Health Organization's Guideline Development Group has updated its guidance on treatments for patients with covid-19.

9 Nov 2023

HMS immunologist unravels the mysteries of how the immune system communicates

The immune system is a crucial part of our survival, regularly fending off wide-ranging attacks on the body, both internal and external.

9 Nov 2023

Open-science drug discovery campaign yields a wealth of data on SARS-CoV-2 main protease

Although the group's work has been freely available since its inception in March 2020, the COVID Moonshot Consortium is finally formally reporting their results.

9 Nov 2023

Preclinical discovery could point the way toward better treatments for type 2 diabetes

A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study by Weill Cornell Medicine investigators.

9 Nov 2023

Tumor-immune interactions predict treatment responses in multiple myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

9 Nov 2023

Drugs News and Research

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

Researchers identify key factors involved in DNA repair mechanism

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Lowering sodium intake can help reduce blood pressure

US reporting system to detect vaccine safety issues may not be meeting its own standards

CÚRAM researchers make breakthrough in cell visualization

Genetically engineered yeast cells produce natural plant product for schizophrenia treatment

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

Developing a synthetic pathology framework: A step towards replacing animal testing

WHO experts update guidance on COVID-19 treatments

HMS immunologist unravels the mysteries of how the immune system communicates

Open-science drug discovery campaign yields a wealth of data on SARS-CoV-2 main protease

Preclinical discovery could point the way toward better treatments for type 2 diabetes

Tumor-immune interactions predict treatment responses in multiple myeloma

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

New device could keep implantable "living pharmacy" cells alive for months

NYU Langone Health performs the world's first whole-eye and partial-face transplant for military veteran

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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