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Researchers find antibody that may protect against wide range of lethal influenza viruses

A nationwide team of researchers has found an antibody that protects mice against a wide range of potentially lethal influenza viruses, advancing efforts to design of a universal vaccine that could either treat or protect people against all strains of the virus.

25 Oct 2019

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the journal Nature on October 23, 2019, examined the brains of mouse models and found that when the gut microbiome is significantly reduced, there are changes in gene expression in the brain’s microglial cells.

24 Oct 2019

Flu antibody could be a key to better treatments for severe flu disease

Researchers have found an antibody that protects mice against a wide range of lethal influenza viruses, according to a study from Washington University School of Medicine in St. Louis, Icahn School of Medicine at Mount Sinai in New York City, and Scripps Research in La Jolla, Calif.

24 Oct 2019

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

Newly discovered protein is key to recycling aging mitochondria

Aging, and the mechanics behind it, remains one of the most closely guarded secrets of life.

24 Oct 2019

Taking blood pressure pills at bedtime best for heart

Chronopharmacology or chronotherapy deals with the effects of a drug when taken at specific time of the day. This variable response to medication is due to the 24 hour biological clock or circadian rhythm of the body say experts.

23 Oct 2019

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body's healthy tissues and organs.

23 Oct 2019

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

A research team from the School of Chinese Medicine at Hong Kong Baptist University has successfully developed a novel aptamer, i.e. a single-stranded piece of DNA, for the treatment of osteogenesis imperfecta (OI) with the aid of artificial intelligence (AI) technology.

23 Oct 2019

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

The National Institute on Drug Abuse, part of the National Institutes of Health, awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders, called SBI-553.

23 Oct 2019

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Jennifer J. Lentz, PhD, Associate Professor at LSU Health New Orleans Neuroscience Center of Excellence and Departments of Otorhinolaryngology, Genetics and Ophthalmology, in collaboration with Robert K. Koenekoop MD, PhD and Professor of Pediatric Surgery, Human Genetics and Ophthalmology at McGill University in Montreal, Quebec, Canada, has been awarded a $1.74 million USD grant to advance research on Usher syndrome.

22 Oct 2019

Fullerene compounds can effectively kill non-small-cell lung carcinoma cells

The team of scientists from Skoltech Center for Energy Science and Technology, the Institute for Problems of Chemical Physics of Russian Academy of Sciences and National Taiwan University have discovered that fullerene compounds can effectively kill non-small-cell lung carcinoma cells and found out the mechanisms behind their anti-tumor activity.

22 Oct 2019

Researchers elucidate properties of blood factor involved in weight loss and aging

Aging is a process that affects all functions of the human body, particularly brain function. However, aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.).

22 Oct 2019

High glucose impairs circadian clock function, may increase cardiovascular risk

High glucose in obesity appears to gum up the works of the circadian clocks inside our cells that help regulate the timing of many body functions across the 24-hour day and drive the risk of cardiovascular disease, scientists say.

22 Oct 2019

Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases

DJ-1 is well known as an important target for the treatment of a number of diseases such as Parkinson's disease. Cantabio has been developing novel small molecule therapeutic program targeting the DJ-1 protein with a focus on Parkinson's and also exploring a number of other disease areas.

21 Oct 2019

Columbia researchers capture new detailed images of a temperature-sensing molecule

Columbia University researchers have captured new detailed images of a temperature-sensing molecule in its open, intermediate, and closed states.

21 Oct 2019

Researchers identify new mechanism by which cancer cells become resistant to ferroptosis

An international team of researchers has found a different way cancer becomes resistant to chemotherapy, suggesting a new target for drugs.

21 Oct 2019

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

Despite advances in cancer survival, more than 90 percent of people with pancreatic cancer die within five years. Most patients with pancreatic tumors (and half of those with colorectal cancers) carry a mutation in the KRAS gene, which normally controls cell growth and death.

21 Oct 2019

New method may offer effective treatment for pancreatic cancer with fewer side effects

Pancreatic cancer is one of the leading causes of cancer-related deaths worldwide. Patients with pancreatic cancer often receive chemotherapy or radiation therapy, which are not always effective and can have toxic side effects.

21 Oct 2019

'Flamenco-style' dancing molecule could form the basis for new longer-lasting sunscreen

A molecule that protects plants from overexposure to harmful sunlight thanks to its flamenco-style twist could form the basis for a new longer-lasting sunscreen, chemists at the University of Warwick have found, in collaboration with colleagues in France and Spain.

18 Oct 2019

Research could open a promising new path to control schistosomiasis

Scientists have isolated a natural chemical that acts as a potent kryptonite against parasitic worms that burrow through human skin and cause devastating health problems.

From PLOS ONE 18 Oct 2019

Molecule News and Research

Researchers find antibody that may protect against wide range of lethal influenza viruses

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

Flu antibody could be a key to better treatments for severe flu disease

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

Newly discovered protein is key to recycling aging mitochondria

Taking blood pressure pills at bedtime best for heart

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Fullerene compounds can effectively kill non-small-cell lung carcinoma cells

Researchers elucidate properties of blood factor involved in weight loss and aging

High glucose impairs circadian clock function, may increase cardiovascular risk

Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases

Columbia researchers capture new detailed images of a temperature-sensing molecule

Researchers identify new mechanism by which cancer cells become resistant to ferroptosis

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

New method may offer effective treatment for pancreatic cancer with fewer side effects

'Flamenco-style' dancing molecule could form the basis for new longer-lasting sunscreen

Research could open a promising new path to control schistosomiasis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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