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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular "crosstalk" in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.

12 Jan 2022

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

The iMolecule group from Skoltech has developed an artificial intelligence-driven solution that uses data on the structure of RNA or DNA molecules to identify sites on them where interaction with potential drug candidates can occur.

11 Jan 2022

New technique could allow more diseases to be safely treated by nanomedicine

Researchers at Penn Medicine have discovered a new, more effective method of preventing the body's own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response that dampens the therapy's effectiveness.

11 Jan 2022

Novel mechanisms controlling tertiary lymphoid structure formation in tumors revealed

Tertiary lymphoid structures are formations that occur outside of the lymphatic system. They contain immune cells and are similar in structure and function to lymph nodes and other lymphoid structures.

11 Jan 2022

Withdrawing steroid treatment found to boost SARS-CoV-2 vaccine-induced immunity in kidney transplant recipients

In a new study, a team of researchers investigated the impact of the fourth dose of a vaccine against COVID-19 in kidney transplant recipients, who had not mounted a humoral immune response to three doses of vaccine.

11 Jan 2022

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

A recent study discussed the expansion of the SARS-CoV-2 CRISPR-Cas detection technology (SHERLOCK) into Variant-specific SHERLOCK (VarLOCK) assays to accurately differentiate between the newly emerging SARS-CoV-2 variants of concern.

11 Jan 2022

Modular super-enhancer regulates gene expression involved in retina development

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell identity.

11 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

International approaches to tackling food fraud

In this interview, we spoke to key members of the Food Authenticity Network to find out more about the increasing problem of food adulteration and the collaborations being made to address it.

From Bruker BioSpin Group 11 Jan 2022

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

A new preprint describes a single-step molecular diagnostic test for the presence of SARS-CoV-2 infection caused by the Omicron variant that is behind the unprecedented rise in cases over the last few weeks.

11 Jan 2022

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

Unique combination of nanomaterials in DNA biosensor enables easier SARS-CoV-2 detection

A recent paper that was published in the Talanta journal dedicated to original reports in pure and applied analytical chemistry presents for the first time the combination of two different nanomaterials – gold nanomaterials (AuNMs) and CDs for the development of an improved electrochemiluminescence (ECL) DNA biosensor.

10 Jan 2022

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Researchers at Université de Montréal have created a nanoantenna to monitor the motions of proteins. Reported this week in Nature Methods, the device is a new method to monitor the structural change of proteins over time – and may go a long way to helping scientists better understand natural and human-designed nanotechnologies.

10 Jan 2022

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Biliary atresia is a rare disease that occurs when a delicate tree-like set of ducts that carry bile from the liver to the intestine becomes scarred and blocked. While some treatments can slow the damage, most children who develop biliary atresia will die without a liver transplant.

10 Jan 2022

Newly developed risk scores can help identify childhood obesity risk

Newly developed risk scores synthesize genetic information into an easy-to-interpret metric that could help clinicians identify young children most at risk of developing obesity.

10 Jan 2022

New genetic mechanism that can cause severe male infertility identified

Scientists at Newcastle University have identified a new genetic mechanism that can cause severe forms of male infertility.

10 Jan 2022

Neutralization of SARS-CoV-2 variants by three-dose mRNA vaccinated kidney transplant recipient sera

In a new study, researchers determined three-dose messenger ribonucleic acid (mRNA) vaccinated kidney transplant recipients’ (KTRs) neutralizing responses against SARS-COV-2 variants, breakthrough coronavirus disease 2019 infection rate, and transplant rejection rate.

10 Jan 2022

Researchers plan to review the effect of SARS-CoV-2 on male reproductive health

In a protocol published in BMJ Open, researchers from the Chengdu University of Traditional Chinese Medicine plan to review current studies in this area.

10 Jan 2022

Strategy for capturing SARS-CoV-2 through functionalized cellulose materials

Researchers from Northeastern University have developed a new, more cost-effective method for immobilizing SARS-CoV-2.

10 Jan 2022

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available for free on the medRxiv* preprint server while it undergoes peer review.

9 Jan 2022

DNA News and Research

Further Reading

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

New technique could allow more diseases to be safely treated by nanomedicine

Novel mechanisms controlling tertiary lymphoid structure formation in tumors revealed

Withdrawing steroid treatment found to boost SARS-CoV-2 vaccine-induced immunity in kidney transplant recipients

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

Modular super-enhancer regulates gene expression involved in retina development

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

International approaches to tackling food fraud

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

Unique combination of nanomaterials in DNA biosensor enables easier SARS-CoV-2 detection

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Maternal transfer of healthier gut bacteria helps neonates to resist biliary atresia

Newly developed risk scores can help identify childhood obesity risk

New genetic mechanism that can cause severe male infertility identified

Neutralization of SARS-CoV-2 variants by three-dose mRNA vaccinated kidney transplant recipient sera

Researchers plan to review the effect of SARS-CoV-2 on male reproductive health

Strategy for capturing SARS-CoV-2 through functionalized cellulose materials

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

Understanding the DNA Damage Response in Innate Immunity eBook

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