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The war against COVID-19: reinfection, vaccines, and herd immunity

A communication published in the journal Epidemiologia aimed to answer several questions concerning neutralizing antibodies against SARS-CoV-2, herd immunity, and COVID-19 vaccines.

4 May 2022

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

In a new study, researchers assessed the efficacy of a third dose of COVID-19 vaccine in anti-CD20 antibody-treated individuals.

4 May 2022

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Researchers determined the threshold neutralizing antibody titer for effective COVID-19 convalescent plasma therapy.

4 May 2022

The effectiveness of shielding strategies for COVID-19

Researchers have used a mathematical model to assess if shielding the most vulnerable group while allowing infection to transmit through low-risk groups is an effective policy to combat the COVID-19 pandemic

4 May 2022

How protection due to vaccination or previous SARS-CoV-2 infection varies for the population of the Czech Republic

The current study aimed to understand how far this reduced vaccine efficacy and the protection conferred by prior infection in terms of Omicron infection, hospitalization, and oxygen supplementation.

4 May 2022

New drug combinations for obesity and diabetes may show greater efficacy than single therapy

Canadian and German researchers are teaming up to identify new drug combinations to treat people with obesity and Type 2 diabetes.

4 May 2022

Study reveals the efficacy of teacher-implemented intervention in reducing learning gaps

New research from Center for BrainHealth® at The University of Texas at Dallas demonstrates that professional development with a focus on neuroscience equips teachers with the tools and confidence to reduce learning gaps in eighth grade students, as measured by State of Texas Assessment of Academic Readiness (STAAR) performance.

4 May 2022

Novel magnetic therapy complements chemotherapy to enhance breast cancer treatment outcomes

Breast cancer is the leading cause of cancer-associated death for women worldwide. While chemotherapy is the mainstream treatment for breast cancer, more than 50% of women undergoing chemotherapy will experience at least one chemotherapy-related adverse side effect.

3 May 2022

Efficacy of affinity resin containing Galanthus nivalis agglutinin against SARS-CoV-2

A new study demonstrated the efficacy of the Galanthus nivalis agglutinin (GNA)-incorporated affinity resin against various SARS-CoV-2 variants.

3 May 2022

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Researchers reviewed the potential clinically relevant mechanisms by which microbiota and microbiota-derived metabolites influence the host immune responses to SARS-CoV-2 infection.

3 May 2022

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

A new study analyzed multivalent messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine constructs against certain β-coronaviruses (β-CoVs).

3 May 2022

Infectivity of SARS-CoV-2 Omicron variant in the intestinal tract

Researchers assessed the infectivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant in the intestinal tract.

3 May 2022

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Glioma is an intracranial malignant tumor that still poses a major clinical challenge due to its highly invasive nature, low cure rate, and high mortality rate.

3 May 2022

Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Scientists from the United States have recently identified a novel approach to rapidly and accurately detect the omicron BA.2.12.1 sub-lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples.

2 May 2022

Combining two cancer drugs can be effective in treating specific type of colorectal cancer, study shows

Researchers at the Case Western Reserve University School Medicine have found that combining two cancer drugs can be effective in treating a specific type of colorectal cancer, according to a new study published in Nature Communications.

2 May 2022

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

Researchers evaluated the importance of the P681 residue within the furin cleavage site of SARS-CoV-2 spike protein in determining the fusogenicity and syncytia formation ability of SARS-CoV-2 strains.

2 May 2022

Higher contact among vaccinated people may negatively influence vaccine effectiveness

In a new study, researchers reported that contact among vaccinated people could influence the effectiveness of COVID-19 vaccines.

2 May 2022

Higher vaccination coverage associated with lower rates of population-level COVID-19 mortality and incidence in the US

By using data representing 80% of the US population, researchers have found that increased vaccination coverage against COVID-19 can be linked to a reduced incidence of cases and deaths.

2 May 2022

$Can fractional doses of COVID-19 vaccines protect against SARS-CoV-2?$

Can fractional doses of COVID-19 vaccines protect against SARS-CoV-2?

A recent research paper posted to the Research Square* preprint server assessed the dose fractionation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.

1 May 2022

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

A recent research paper posted to the bioRxiv* preprint server demonstrated that a cocktail of two synergetic antibodies extensively neutralized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including Omicron BA.1 and BA.2.

1 May 2022

Efficacy News and Research

The war against COVID-19: reinfection, vaccines, and herd immunity

Evaluating a third SARS-CoV-2 mRNA vaccine in anti-CD20-treated patients

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

The effectiveness of shielding strategies for COVID-19

How protection due to vaccination or previous SARS-CoV-2 infection varies for the population of the Czech Republic

New drug combinations for obesity and diabetes may show greater efficacy than single therapy

Study reveals the efficacy of teacher-implemented intervention in reducing learning gaps

Novel magnetic therapy complements chemotherapy to enhance breast cancer treatment outcomes

Efficacy of affinity resin containing Galanthus nivalis agglutinin against SARS-CoV-2

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

Infectivity of SARS-CoV-2 Omicron variant in the intestinal tract

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Combining two cancer drugs can be effective in treating specific type of colorectal cancer, study shows

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

Higher contact among vaccinated people may negatively influence vaccine effectiveness

Higher vaccination coverage associated with lower rates of population-level COVID-19 mortality and incidence in the US

Can fractional doses of COVID-19 vaccines protect against SARS-CoV-2?

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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