Efficacy News and Research

RSS

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

Researchers at the Kennedy Institute, University of Oxford, led by Professor Jagdeep Nanchahal have demonstrated the efficacy of the anti-TNF drug adalimumab for patients with early-stage Dupuytren's disease.

30 Apr 2022

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

A new study describes the development of new molecules with inhibitory activity against the SARS-CoV-2 viral main protease (Mpro) enzyme, based on rattlesnake venom.

29 Apr 2022

Probenecid shows activity against respiratory syncytial virus

A new study describes the antiviral activity of the approved drug probenecid against respiratory syncytial virus.

29 Apr 2022

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

A recent article published in the Med journal reported that the SARS-CoV-2 booster vaccinations enhance the SARS-CoV-2 Omicron sublineage neutralizations.

29 Apr 2022

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Researchers discussed the validity of the equation derived by Khoury et al. and reported by Muena et al. regarding the immunological correlate of protection to predict the efficacy of new coronavirus vaccines in a real-world setting.

29 Apr 2022

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

In a recent randomized clinical trial of hospitalized patients with COVID-19 and cardio-metabolic risk factors, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin did not significantly reduce patients' risk of organ failure, kidney problems, or death compared with placebo, although numerically fewer participants treated with dapagliflozin experienced these outcomes. The findings are published in CJASN.

29 Apr 2022

Lower COVID-19 mortality among physically active individuals in Sub-Saharan Africa

Researchers enlisted the benefits of physical activity and being outdoors in reducing the incidence, prevalence, and severity of COVID-19 among low-income populations.

29 Apr 2022

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

Spinal cord stimulation (SCS) for chronic pain involves delivering low levels of electricity directly into the spinal cord using an implanted device, which modifies or blocks nerve activity to minimize the sensation of pain reaching the brain.

28 Apr 2022

UrFU researchers propose the use of polyoxometallate nanoclusters as chemotherapy drug carrier

Researchers at Ural Federal University have proposed the use of polyoxometallate nanoclusters as a carrier for chemotherapy drug. It will help to deliver medications precisely to the focus of a pathological process, such as a cancerous tumor, without toxic effects on healthy cells.

28 Apr 2022

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma.

28 Apr 2022

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

Scientists explore mixing of unvaccinated and vaccinated and implications for SARS-CoV-2 transmission

A recent study published in the Canadian Medical Association Journal (CMAJ) explored the effects of unvaccinated and vaccinated population mixing on coronavirus disease 2019 (COVID-19) transmission.

28 Apr 2022

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the cancer - even metastatic cancer - and prevents it from recurring.

27 Apr 2022

Efficacy News and Research

Trial shows the efficacy of anti-TNF drug for patients with early-stage Dupuytren's disease

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

Probenecid shows activity against respiratory syncytial virus

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

Lower COVID-19 mortality among physically active individuals in Sub-Saharan Africa

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

UrFU researchers propose the use of polyoxometallate nanoclusters as chemotherapy drug carrier

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Scientists explore mixing of unvaccinated and vaccinated and implications for SARS-CoV-2 transmission

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

Novel plug-and-play multi-organ chip can be customized to the patient

Study describes ultra-structure of Nipah virus surface glycoprotein

New findings show rise in racial disparities as availability of proton beam therapy increased in the U.S.

Researchers identify four new target molecules for future personalized MS treatment

Survey identifies maternal attitude towards COVID-19 vaccination during pregnancy

Comparative analysis of transcriptional responses across 13 different vaccines

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News