Genomic News and Research

RSS

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

9 Nov 2017

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

An analysis of the medical records of patients treated at Massachusetts General Hospital (MGH) for an often-mysterious condition involving damage to small nerve fibers supports the hypothesis that some cases are caused by autoimmune disease and also identifies the first effective treatment option.

9 Nov 2017

Repositive joins with experts from the U.S. to support development of NIH Data Commons Pilot Phase

Repositive, the Cambridge-based UK start-up that launched the largest global genomic data portal for research, has joined forces with leading data experts from the US to support the development of the NIH Data Commons Pilot Phase, designed to transform the way public biomedical data is stored and analyzed.

8 Nov 2017

New study finds enhanced impact of drug combination for FAP patients

People with an inherited syndrome called familial adenomatous polyposis (FAP) have a 100% lifetime risk of developing colorectal cancer if they do not seek appropriate medical care.

7 Nov 2017

FDA approves first targeted cancer treatment based on basket study

The US Food and Drug Administration has announced that it has approved the drug vemurafenib for the treatment of patients with BRAF V600-mutant Erdheim-Chester disease (ECD).

7 Nov 2017

Researchers identify new neuroprotective factor that holds potential to help people with glaucoma

A research team led by scientists at the Krembil Research Institute in Toronto has identified a new neuroprotective factor that has the potential to help people suffering from the common blinding disease glaucoma.

7 Nov 2017

Pioneering research to grow mini bowel cancer tumor models in the lab

Charity Cancer Research UK has awarded the University of Birmingham £1.5 million to fund a five-year research program aimed at finding new treatments for bowel cancer.

6 Nov 2017

Gut bacteria can influence how cancer responds to immunotherapy

Bacteria that live in the human digestive tract can influence how cancer responds to immunotherapy, opening a new avenue for research to improve treatment, a team led by researchers at The University of Texas MD Anderson Cancer Center reports in the journal Science.

2 Nov 2017

Study solves critical piece of deafness puzzle by identifying long non-coding RNAs

A new Tel Aviv University study solves a critical piece of the puzzle of human deafness by identifying the first group of long non-coding RNAs (lncRNAs) in the auditory system.

2 Nov 2017

University of Birmingham researchers receive £1.5 million to find new treatments for bowel cancer

Charity Cancer Research UK has awarded the University of Birmingham £1.5 million to fund a five-year research program aimed at finding new treatments for bowel cancer.

2 Nov 2017

Discovery of genetic markers could guide individualized treatments for advanced prostate cancer

Researchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced prostate cancer.

2 Nov 2017

Researchers compile biggest recorded collection of families with epilepsy

Researchers from Swansea University Medical School have joined up with five other centers from around the world to compile the biggest recorded collection of families with forms of epilepsy where genetics may play a part in the recurring feature of the condition.

2 Nov 2017

Researchers show how changes along lining of mammary ducts can lead to breast cancer

Breast cancer researchers have mapped early genetic alterations in normal-looking cells at various distances from primary tumors to show how changes along the lining of mammary ducts can lead to disease.

1 Nov 2017

PARP inhibitors may have efficacy in selected TNBC patients outside of germline BRCA mutation

The investigational PARP inhibitor talazoparib caused regression of patient-derived xenografts (PDXs) of triple-negative breast cancers (TNBC) that had BRCA mutations and also those that did not have BRCA mutations but had other alterations in DNA damage-repair pathways.

1 Nov 2017

Non-invasive diagnostic tool developed for early detection of ovarian cancer

Investigators from Brigham and Women's Hospital and Dana-Farber Cancer Institute are leveraging the power of artificial intelligence to develop a new technique to detect ovarian cancer early and accurately.

31 Oct 2017

Our chromosomes also wrinkle with age, research shows

Grey hair, wisdom, and wrinkles on our skin mark us as we age, but it's the more subtle changes beneath the surface that make us old. Now, researchers have discovered that our chromosomes also wrinkle with age, changing how our immune system renews itself.

31 Oct 2017

Sanford Health to evaluate effectiveness of non-opioid medications

Sanford Health is one of three sites in the U.S. to launch a study to determine if non-opioid medications are as effective in managing pain after carpal-tunnel surgery.

30 Oct 2017

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time.

27 Oct 2017

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Precision Medicine in oncology, where genetic testing is used to determine the best drugs to treat cancer patients, is not always so precise when applied to some of the world's more diverse populations, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope, and the Keck School of Medicine of the University of Southern California.

27 Oct 2017

Dream Team plans to stop pancreatic cancer before symptoms occur

Deeply entrenched and mature by the time it's found, pancreatic cancer is one of the hardest to defeat. A Dream Team assembled by Stand Up to Cancer and led by an investigator at The University of Texas MD Anderson Cancer Center will test new ways to find the disease in its emerging, more vulnerable phase in people who are at high risk for developing it.

26 Oct 2017

Genomic News and Research

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

MGH researchers identify first effective treatment option for autoimmune small-fiber polyneuropathy

Repositive joins with experts from the U.S. to support development of NIH Data Commons Pilot Phase

New study finds enhanced impact of drug combination for FAP patients

FDA approves first targeted cancer treatment based on basket study

Researchers identify new neuroprotective factor that holds potential to help people with glaucoma

Pioneering research to grow mini bowel cancer tumor models in the lab

Gut bacteria can influence how cancer responds to immunotherapy

Study solves critical piece of deafness puzzle by identifying long non-coding RNAs

University of Birmingham researchers receive £1.5 million to find new treatments for bowel cancer

Discovery of genetic markers could guide individualized treatments for advanced prostate cancer

Researchers compile biggest recorded collection of families with epilepsy

Researchers show how changes along lining of mammary ducts can lead to breast cancer

PARP inhibitors may have efficacy in selected TNBC patients outside of germline BRCA mutation

Non-invasive diagnostic tool developed for early detection of ovarian cancer

Our chromosomes also wrinkle with age, research shows

Sanford Health to evaluate effectiveness of non-opioid medications

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Dream Team plans to stop pancreatic cancer before symptoms occur

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News