immunity News and Research

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Convalescent plasma shows CD8+ T cell responses to SARS-CoV-2 variants

Researchers in the United States have conducted a study suggesting that individuals who have recovered from or been vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) should maintain effective CD8+ T-cell responses against the major variants that have recently emerged.

17 Feb 2021

Nasal antiviral blocks SARS-CoV-2 transmission in ferrets

A nasal antiviral created by researchers at Columbia University Vagelos College of Physicians and Surgeons blocked transmission of SARS-CoV-2 in ferrets, suggesting the nasal spray also may prevent infection in people exposed to the new coronavirus, including recent variants.

17 Feb 2021

Immune system directly links personality to long-term mortality risk, study reveals

Ground-breaking research led by University of Limerick has revealed for the first time that the immune system directly links personality to long-term risk of death.

17 Feb 2021

The origin of SARS-CoV-2 furin cleavage site remains a mystery

A new study discusses the origin of the furin cleavage site on the SARS-CoV-2 spike protein, which is responsible for the virus’s relatively high infectivity compared to relatives in the betacoronavirus subgenus.

17 Feb 2021

What are the main food safety concerns associated with the COVID-19 pandemic?

A new study deals with the main food safety concerns associated with the COVID-19 pandemic.

17 Feb 2021

Development of malaria vaccines deserves urgent attention just like COVID-19

Developing vaccines to fight malaria deserves urgent attention just like COVID-19, argues Damaris Matoke-Muhia.

17 Feb 2021

Probiotics may be beneficial in COVID-19 treatment

A new study explores the role of common probiotics in managing the disease, which could prove to be of great value, given the emergence of new variants and the broad spectrum of clinical disease in COVID-19.

17 Feb 2021

New type of antibody marks infected cells, makes them visible to the immune system

Scientists at Cardiff University have discovered a unique way to target a common virus that affects one in 200 newborn babies in the UK but for which there is only limited treatments available.

17 Feb 2021

Rich nations should not engage in "vaccine nationalism”, says Binghamton University expert

Rich nations should not engage in "vaccine nationalism" and keep the COVID-19 vaccine to themselves when poorer nations need them, according to Nicole Hassoun, professor of philosophy at Binghamton University, State University of New York. Hassoun's paper, "Against Vaccine Nationalism," was published in the Journal of Medical Ethics.

17 Feb 2021

Scientists to develop highly sensitive antibody tests for infection caused by all coronaviruses

Scientists at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health and SunYat-Sen University in China have set the stage for the development of highly sensitive antibody tests for infection with all known human coronaviruses, including new variants of SARS-CoV-2.

17 Feb 2021

Antibody testing is key to understand immune response to SARS-CoV-2

While PCR testing has been used widely for COVID-19 diagnosis, it only provides information on who is currently infected. Antibody testing can tell who has been previously exposed to SARS-CoV-2, the virus that causes COVID-19, a metric that is essential for tracking spread across a population.

17 Feb 2021

Anti-immigrant vitriol complicates vaccine rollout in Southern states

In eastern Tennessee, doctors have seen firsthand how a hard-line immigration policy can affect the health and well-being of a community.

16 Feb 2021

British and South African SARS-CoV-2 variants show some resistance to neutralizing antibodies

Researchers in France report impaired neutralization of two new SARS-CoV-2 variants by antibodies induced by vaccination or natural infection.

16 Feb 2021

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

A new preprint research paper posted to the bioRxiv server provides a greater understanding of the aspect of humoral immunity against the virus – the plasma cells that pour out a flood of specific antibodies targeting various epitopes on the pathogen.

16 Feb 2021

Mink-derived SARS-CoV-2 mutations reduce antibody effectiveness

A new preprint research paper posted to the bioRxiv* server shows that these mutations disrupt inhibition by neutralizing antibodies, both natural and therapeutic.

16 Feb 2021

Nanoparticle COVID-19 vaccine stimulates robust and long lasting immunity in primates

In the study, published on the preprint server bioRxiv, the team evaluated the ability of AS03, CpG 1018 formulated in Alum, the TLR-7 agonist adsorbed to Alum (AS37), the squalene-in-water emulsion (O/W), and Alum to boost protective immunity against SARS-CoV-2.

15 Feb 2021

Naïve B cells can neutralize SARS-CoV-2 via RBD recognition

A new preprint research paper posted to the bioRxiv server demonstrates the potential of using the pre-existing protective responses to produce a broad-spectrum neutralizing response against not just SARS-CoV-2 but other future pathogens.

14 Feb 2021

New mouse model of SARS-CoV-2 infection reflects features of human infection

Now, a new preprint research paper posted to the bioRxiv server reports the development of a modified mouse model that allows productive SARS-CoV-2 infection of the mouse lungs, as well as the exploration of type I and III interferon responses in this condition.

14 Feb 2021

SARS-CoV-2's resistance to remdesivir in vitro

A new preprint research paper posted to the bioRxiv server discusses the emergence of mutations in the SARS-CoV-2 virus, allowing it to escape the effects of the most commonly used antiviral drug, remdesivir.

14 Feb 2021

Study shows that SRC-3 also regulates human immune T regulatory cells

A study led by researchers at Baylor College of Medicine reveals a novel role of the steroid receptor coactivator 3 (SRC-3/NCOA3), a protein crucial for steroid hormone function and a prognostic marker for aggressive human breast and other cancers.

12 Feb 2021

immunity News and Research

Convalescent plasma shows CD8+ T cell responses to SARS-CoV-2 variants

Nasal antiviral blocks SARS-CoV-2 transmission in ferrets

Immune system directly links personality to long-term mortality risk, study reveals

The origin of SARS-CoV-2 furin cleavage site remains a mystery

What are the main food safety concerns associated with the COVID-19 pandemic?

Development of malaria vaccines deserves urgent attention just like COVID-19

Probiotics may be beneficial in COVID-19 treatment

New type of antibody marks infected cells, makes them visible to the immune system

Rich nations should not engage in "vaccine nationalism”, says Binghamton University expert

Scientists to develop highly sensitive antibody tests for infection caused by all coronaviruses

Antibody testing is key to understand immune response to SARS-CoV-2

Anti-immigrant vitriol complicates vaccine rollout in Southern states

British and South African SARS-CoV-2 variants show some resistance to neutralizing antibodies

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

Mink-derived SARS-CoV-2 mutations reduce antibody effectiveness

Nanoparticle COVID-19 vaccine stimulates robust and long lasting immunity in primates

Naïve B cells can neutralize SARS-CoV-2 via RBD recognition

New mouse model of SARS-CoV-2 infection reflects features of human infection

SARS-CoV-2's resistance to remdesivir in vitro

Study shows that SRC-3 also regulates human immune T regulatory cells

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