Clinical Trial News and Research

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Sex-specific difference could prevent Alzheimer's treatment from working in females

A University of Ottawa study has found a specific Alzheimer's treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.

21 Dec 2020

First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries

The first patient has enrolled in a Phase II clinical trial evaluating a stem cell therapy for the potential early treatment of traumatic injuries and their subsequent complications at The University of Texas Health Science Center at Houston.

21 Dec 2020

Effective vaccine strategies for New South Wales Australia under different vaccine supply

Researchers say mass immunization will terminate the disease, or immunizing 66% of the population with a 90% efficacy vaccine will achieve herd immunity.

21 Dec 2020

Many US health experts underestimated the coronavirus … until it was too late

A year ago, while many Americans were finishing their holiday shopping and finalizing travel plans, doctors in Wuhan, China, were battling a mysterious outbreak of pneumonia with no known cause.

21 Dec 2020

Cross-reactive coronavirus antibodies shape COVID-19 convalescent plasma functionality

The onset of the current COVID-19 pandemic revealed the seventh known pathogenic human coronavirus, SARS-CoV-2.

21 Dec 2020

FDA issues first emergency use authorization for second COVID-19 vaccine

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the second vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

21 Dec 2020

Pioneering new eye test may predict wet AMD three years before symptoms develop

A pioneering new eye test, developed by scientists at UCL in collaboration with the Western Eye Hospital, London, may predict wet AMD, a leading cause of severe sight loss, three years before symptoms develop.

18 Dec 2020

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

Cologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer Ingelheim today announced the initiation of Phase 1/2a clinical investigation of BI 767551, a new SARS-CoV-2 neutralizing antibody.

18 Dec 2020

UVA researcher evaluates a new approach to managing type 2 diabetes

A researcher at the University of Virginia School of Medicine is testing what he calls a "radically different" approach to managing type 2 diabetes for those who can't or don't want to lose weight.

18 Dec 2020

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

A new multicenter study has shown that blinded crossover and continued follow-up of trial participants can help assess vaccine durability and potential delayed enhancement of disease.

18 Dec 2020

Novel device may help restore total eye function

An international consortium of researchers is developing a new method to bring eyes back to life from deceased body donors for clinical research purposes.

18 Dec 2020

FDA approves pembrolizumab as first-line treatment for colorectal cancer

The FDA recently approved the immunotherapy drug pembrolizumab as a first-line treatment for patients with certain types of advanced colorectal cancer. This is the 9th FDA approval supported by Stand Up To Cancer® (SU2C) research.

18 Dec 2020

Vi-DT typhoid conjugate vaccine met primary endpoints in phase III study

Vi-DT typhoid conjugate vaccine, developed jointly by the International Vaccine Institute (IVI) and SK bioscience, has met the primary endpoints in a phase III study in Nepal.

17 Dec 2020

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

17 Dec 2020

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

The ASH Research Collaborative and the International Society of Haemostasis and Thrombosis, two organizations with multidisciplinary expertise in blood clotting and bleeding disorders, have developed a toolkit to help clinical researchers from across medical disciplines design clinical trials that further the understanding of blood clotting events associated with COVID-19.

17 Dec 2020

Study shows benefits of integrated palliative and oncology care for patients with advanced AML

A first-of-its-kind intervention integrating palliative care early in the course of cancer therapy for patients with advanced acute myeloid leukemia (AML), a highly aggressive cancer of the blood and bone marrow, resulted in substantial improvements in patients' quality of life, mood and end-of-life care, a team of investigators has found.

17 Dec 2020

Additional data demonstrates positive results of pridopidine drug on Total Functional Capacity

Positive results from additional analyses of PRIDE-HD and Open-HART trials with pridopidine published in a peer-reviewed journal, The Journal of Huntington's Disease.

17 Dec 2020

LOOP technique is an effective alternative for treating skin abscesses

The LOOP technique for incision and drainage (I&D) of abscesses in adults is a safe and effective alternative to the traditional I & D with packing and may offer an alternative to the standard regimen in the treatment of uncomplicated skin abscesses in pediatric patients.

17 Dec 2020

Intensive interventions in type 2 diabetes reduce risk of cardiovascular autonomic neuropathy

Intensive interventions to reduce blood glucose and blood pressure levels in type 2 diabetes reduce the risk of developing cardiovascular autonomic neuropathy (CAN), a frequent but underdiagnosed complication of diabetes that can be life-threatening.

17 Dec 2020

Oral hormone therapy significantly alters the metabolome of postmenopausal women

Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women.

16 Dec 2020

Clinical Trial News and Research

Sex-specific difference could prevent Alzheimer's treatment from working in females

First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries

Effective vaccine strategies for New South Wales Australia under different vaccine supply

Many US health experts underestimated the coronavirus … until it was too late

Cross-reactive coronavirus antibodies shape COVID-19 convalescent plasma functionality

FDA issues first emergency use authorization for second COVID-19 vaccine

Pioneering new eye test may predict wet AMD three years before symptoms develop

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

UVA researcher evaluates a new approach to managing type 2 diabetes

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

Novel device may help restore total eye function

FDA approves pembrolizumab as first-line treatment for colorectal cancer

Vi-DT typhoid conjugate vaccine met primary endpoints in phase III study

Regulating fas protein may be a route to prevent cancer relapse after immunotherapy

New toolkit aims to maximize high-quality collection of thrombosis data in COVID-19 clinical studies

Study shows benefits of integrated palliative and oncology care for patients with advanced AML

Additional data demonstrates positive results of pridopidine drug on Total Functional Capacity

LOOP technique is an effective alternative for treating skin abscesses

Intensive interventions in type 2 diabetes reduce risk of cardiovascular autonomic neuropathy

Oral hormone therapy significantly alters the metabolome of postmenopausal women

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