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RXi Pharmaceuticals acquires self-delivering rxRNA technology platform from Advirna

RXi Pharmaceuticals Corporation, a biopharmaceutical company pursuing the development and commercialization of proprietary therapeutics based on RNA interference (RNAi), today announced that it has recently acquired direct ownership of technology for which it had previously exercised its option to exclusively license from Advirna LLC.

25 Sep 2009

Current stem cell applications to be discussed at NJIT

Stem cell researcher Treena Livingston Arinzeh will discuss current stem cell applications at NJIT, including the regeneration of bone and cartilage for bone fracture and osteoarthritis treatments, spinal cord repair, and liver regeneration at NJIT's first Research Caf.

25 Sep 2009

Caliper Life Sciences unveils XenoLight Rediject reagents series at WMIC

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today introduced a series of XenoLight Rediject reagents at the World Molecular Imaging Congress (WMIC) in Montreal, Canada. Rediject D-Luciferin Ultra is the latest in an expanding range of XenoLight reagents for Caliper's IVIS optical imaging systems.

25 Sep 2009

Chronic sleep deprivation linked to early incidence of Alzheimer's brain plaques

Chronic sleep deprivation in a mouse model of Alzheimer's disease makes Alzheimer's brain plaques appear earlier and more often, researchers at Washington University School of Medicine in St. Louis report online this week in Science Express.

25 Sep 2009

CTRC commences patient enrolment in Phase 2 clinical trial of REOLYSIN for metastatic melanoma

Oncolytics Biotech Inc. announced today that the Cancer Therapy Research Center at the University of Texas Health Science Center (CTRC) has started patient enrolment in a U.S. Phase 2 clinical trial using intravenous administration of REOLYSIN(R) in combination with paclitaxel and carboplatin in patients with metastatic melanoma.

24 Sep 2009

VisEn launches new imaging agent for monitoring key hypertension and renal disease biomarker

VisEn Medical Inc., a leader in fluorescence in vivo imaging from research through medicine, announced today the commercial launch of its new ReninSense680(TM) FAST imaging agent for measuring and monitoring a key hypertension and renal disease biomarker in vivo.

24 Sep 2009

Magnetic nanoworms and nanocrystals deliver siRNA to tumors

Small pieces of nucleic acid known as short interfering RNAs, or siRNAs, can turn off the production of specific proteins, a property that makes them one of the more promising new classes of anticancer drugs in development. Indeed, at least two siRNA-based anticancer therapies, both delivered to tumors in nanoparticles, have begun human clinical trials.

23 Sep 2009

New Fluorescence Molecular Tomography imaging systems from VisEn Medical

VisEn Medical Inc., a leader in fluorescence in vivo imaging from research through medicine, announced the launch and availability of a new Fluorescence Molecular Tomography (FMT) imaging system -- the FMT 1500, and an advanced version of its FMT 2500, the FMT 2500 LX.

23 Sep 2009

Philips and Bruker sign MOU to develop new imaging technology

At the 2009 World Molecular Imaging Congress (WMIC) in Montreal, Royal Philips Electronics (NYSE: PHG, AEX: PHI) and Bruker BioSpin, a division of Bruker Corporation, today announced that they have signed a memorandum of understanding (MOU) for the development of Magnetic Particle Imaging (MPI) scanners, a new imaging technology, for the preclinical market.

From Philips Healthcare 23 Sep 2009

Preclinical data on Protalix Biotherapeutics' antiTNF released

Protalix Biotherapeutics, Inc., reported today preclinical data on pr-antiTNF, a biosimilar version of etanercept (Enbrel). Produced using the Company’s proprietary ProCellEx technology, pr-antiTNF is a plant cell expressed recombinant fusion protein made from the soluble form of the human TNF receptor (TNFR), fused to the Fc component of a human antibody IgG1 domain. Pr-antiTNF has an identical amino acid sequence to Enbrel.

23 Sep 2009

New sirolimus-eluting stent shows greater neointimal suppression than PES

A new type of sirolimus-eluting stent (SES) successfully showed significantly greater neointimal suppression than the paclitaxel-eluting stent (PES) with greater vessel wall integrity surrounding the stent, confirming the finding of superiority of the SES over the PES stent for the trial's primary endpoint of in-stent late loss.

22 Sep 2009

Industrial lipases launched by EUCODIS Bioscience

EUCODIS Bioscience, a company developing, customizing, manufacturing, and marketing enzymes for the chemical industry, announced today that it has launched the first enzymes of its lipase portfolio. EUCODIS Bioscience currently offers 12 lipases that have been selected to cover a broad range of potential industrial applications.

22 Sep 2009

Importance of residual thymopoiesis in aged adults

Doctor Manuel Leal is managing the Experimental Immune Virology Laboratory (in Virgen del Rocío University Hospital and Instituto de Biomedicina de Sevilla (IBIS), where clinic and basic science researchers work) where he leads a project to establish the functional nature of the thymus gland in adults. So far, it has been proven that this gland keeps on producing lymphocytes in the old age (Ferrando-Martínez et al. AGE, in press), which is a novelty because until very recently it was considered that this organ lost its immune capacity after the puberty.

22 Sep 2009

Research reveals binge drinking weakens the body's ability to fight off infection

As if a bad hangover wasn't enough of a deterrent, new research has shown how binge drinking weakens the body's ability to fight off infection for at least 24 hours afterwards. The study, published today in the open access journal BMC Immunology, focused on the effect of heavy drinking on toll-like receptor 4 (TLR4), a protein that has an important role in immune system activation.

17 Sep 2009

Medivir presented preclinical data from its cathepsin K inhibitor program at the ASBMR meeting

Medivir (STO:MVIRB) presented preclinical data on two candidate drugs (MIV-710, MIV-711) from its cathepsin K inhibitor program in a poster session during the ASBMR (American Society for Bone and Mineral Research) meeting.

16 Sep 2009

RXi Pharmaceuticals to present in vivo data of rxRNA compounds

RXi Pharmaceuticals Corporation, a biopharmaceutical company pursuing the development and commercialization of proprietary therapeutics based on RNA interference (RNAi), today announced that it will be presenting new in vivo data on its self-delivering rxRNA compounds at a number of upcoming scientific conferences, detailed below.

16 Sep 2009

LEAD Therapeutics' LT-29 antibiotic effective against most common antibiotic resistant bacteria

LEAD Therapeutics, a privately held drug discovery company, announced the discovery of a novel antibiotic with potent activity against many of the most common antibiotic resistant bacteria.

16 Sep 2009

NIBIB awards University of Miami a $735,000 grant to develop a bioreactor system for tissue engineering

A new grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the National Institutes of Health (NIH), will provide funding for University of Miami (UM) College of Engineering researchers to develop a novel bioreactor system that will control mechano-electrochemical environment for tissue growth and also provide on-line monitoring for the properties of engineered tissues.

16 Sep 2009

Calcium stones and cell death is linked to prolonged stressful conditions

Study shows prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases such as atherosclerosis, diabetes and neurodegeneration

15 Sep 2009

Altair announces positive Phase I results for AIR645 in treating asthma

Altair Therapeutics, Inc., a privately-held, biopharmaceutical company developing novel therapeutics for respiratory diseases, today announced positive results from a phase I multiple dose safety and pharmacokinetic study of its lead product, once-weekly inhaled AIR645 in healthy adults and mild asthmatics.

14 Sep 2009

in vivo News and Research

RXi Pharmaceuticals acquires self-delivering rxRNA technology platform from Advirna

Current stem cell applications to be discussed at NJIT

Caliper Life Sciences unveils XenoLight Rediject reagents series at WMIC

Chronic sleep deprivation linked to early incidence of Alzheimer's brain plaques

CTRC commences patient enrolment in Phase 2 clinical trial of REOLYSIN for metastatic melanoma

VisEn launches new imaging agent for monitoring key hypertension and renal disease biomarker

Magnetic nanoworms and nanocrystals deliver siRNA to tumors

New Fluorescence Molecular Tomography imaging systems from VisEn Medical

Philips and Bruker sign MOU to develop new imaging technology

Preclinical data on Protalix Biotherapeutics' antiTNF released

New sirolimus-eluting stent shows greater neointimal suppression than PES

Industrial lipases launched by EUCODIS Bioscience

Importance of residual thymopoiesis in aged adults

Research reveals binge drinking weakens the body's ability to fight off infection

Medivir presented preclinical data from its cathepsin K inhibitor program at the ASBMR meeting

RXi Pharmaceuticals to present in vivo data of rxRNA compounds

LEAD Therapeutics' LT-29 antibiotic effective against most common antibiotic resistant bacteria

NIBIB awards University of Miami a $735,000 grant to develop a bioreactor system for tissue engineering

Calcium stones and cell death is linked to prolonged stressful conditions

Altair announces positive Phase I results for AIR645 in treating asthma

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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