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CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

2 Feb 2024

$Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery$

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

A large multicenter clinical trial co-led by University of Maryland School of Medicine researchers large multicenter clinical trial co-led by University of Maryland School of Medicine researchers found that an antiseptic containing iodine resulted in about one-quarter fewer post-surgical infections in patients with limb fractures compared to another frequently used skin antiseptic.

2 Feb 2024

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.

2 Feb 2024

New molecule is one step closer to becoming a treatment for Phelan-McDermid syndrome

A molecule created at the University of Auckland is one step closer to becoming a treatment for an extremely rare and severely debilitating neurological disorder called Phelan-McDermid syndrome.

2 Feb 2024

Study says parents may overshoot fluoride toothpaste dose for toddlers, risking dental fluorosis

Study finds parents significantly overdose children with fluoride toothpaste, suggesting a shift to fluoride-free alternatives to prevent overconsumption and potential fluorosis.

1 Feb 2024

High maternal cortisol levels linked to unexpected birth problems

A snippet of hair can reveal a pregnant person's stress level and may one day help warn of unexpected birth problems, a study indicates.

1 Feb 2024

Researchers develop new method to study liver function and disease

Researchers at Karolinska Institutet in Sweden have developed a method to study liver function and disease without requiring invasive procedures.

1 Feb 2024

Transforming global food system could unlock trillions in economic gains

The Food System Economics Commission's study reveals transforming global food systems could yield economic gains of up to $10 trillion annually, with implementation costs being a fraction of global GDP.

31 Jan 2024

Parents open to veggies for kids' breakfast, study finds

Study reveals parents are open to introducing vegetables in their children's breakfast, recognizing health benefits despite societal norms and practical challenges.

31 Jan 2024

Evidence from Malawi: Typhoid conjugate vaccine provides protection for up to four years

Study shows that a single dose of typhoid conjugate vaccine provides over four years of protection against typhoid fever in Malawian children, proving effective across all age groups.

31 Jan 2024

High dietary intake of fish and vegetables in infancy may protect against IBD

Having a high dietary intake of fish and vegetables at 1 year of age, and a low intake of sugar beverages, seems to protect against inflammatory bowel disease

31 Jan 2024

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) - soft tissue tumors that are stubbornly resistant to chemotherapy and radiation - according to a laboratory study led by researchers at the Johns Hopkins Kimmel Cancer Center.

31 Jan 2024

American Heart Association launches initiative to close CPR knowledge gap, save lives

A new survey conducted by the American Heart Association, which is marking one hundred years of service saving lives, suggests that increased visibility of the need for CPR has had a positive impact on someone's willingness to respond if they are bystanders in a cardiac emergency.

31 Jan 2024

Study finds links between prenatal substance exposure and childhood mental health

An observational study found links between prenatal substance exposure and mental health in children 10–12, but also found that controlling for environment and genetics eliminated many associations.

31 Jan 2024

Scientists identify highly infectious, antibiotic-resistant E. coli strain in China

A new type of E. coli that is both highly infectious and resistant to some antibiotics has been discovered.

31 Jan 2024

High diet quality in early life associated with reduced risk of IBD

A high quality diet at the age of 1 may curb the subsequent risk of inflammatory bowel disease, suggests a large long term study, published online in the journal Gut.

31 Jan 2024

Medical clowns boost sleep quality and reduce hospital stay for children, study finds

Researchers evaluated the impact of medical clown interventions on sleep quality and hospital stay duration in pediatric patients.

31 Jan 2024

Maternal happiness during pregnancy linked to child's brain development

Study reveals that maternal emotional well-being during pregnancy is linked to significant brain development benefits in children, particularly in the hippocampal volume of female offspring.

30 Jan 2024

Scientists regenerate fully functional urinary bladder tissue using a non-human primate model

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University succeeded in regenerating fully functional urinary bladder tissue in a long-term study utilizing a non-human primate model.

30 Jan 2024

Children News and Research

CAR T cells target senescent cells, improve healthspan in mice

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

New molecule is one step closer to becoming a treatment for Phelan-McDermid syndrome

Study says parents may overshoot fluoride toothpaste dose for toddlers, risking dental fluorosis

High maternal cortisol levels linked to unexpected birth problems

Researchers develop new method to study liver function and disease

Transforming global food system could unlock trillions in economic gains

Parents open to veggies for kids' breakfast, study finds

Evidence from Malawi: Typhoid conjugate vaccine provides protection for up to four years

High dietary intake of fish and vegetables in infancy may protect against IBD

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

American Heart Association launches initiative to close CPR knowledge gap, save lives

Study finds links between prenatal substance exposure and childhood mental health

Scientists identify highly infectious, antibiotic-resistant E. coli strain in China

High diet quality in early life associated with reduced risk of IBD

Medical clowns boost sleep quality and reduce hospital stay for children, study finds

Maternal happiness during pregnancy linked to child's brain development

Scientists regenerate fully functional urinary bladder tissue using a non-human primate model

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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