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Subcutaneous fat protects against brain inflammation in females

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

14 Dec 2022

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Researchers elucidated the mechanisms of long-term T lymphocyte lodgement in tissues other than lymphoid tissues and the reasons for the transient residency of specific subsets of tissue-resident memory T (TRM) lymphocytes.

14 Dec 2022

Study seeks to look for a better treatment for endometriosis

Up to 15% of women of reproductive age in the United States suffer from endometriosis, a condition characterized by pelvic pain, menstrual cramps and infertility.

14 Dec 2022

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Structural racism has not only psychosocial but also biological consequences. Discrimination has been shown to contribute to mental and physical disorders including obesity, depression, and addiction, but the biological pathways from a social experience to its impacts on the body remain unknown.

13 Dec 2022

Bad cholesterol and high blood pressure may be associated with higher risk of cardiovascular disease

High levels of lipoprotein(a), a type of "bad" cholesterol, may be associated with an 18-20% higher risk of cardiovascular disease among people who have hypertension, however, CVD risk was not higher among those without hypertension, according to new research published today in Hypertension, an American Heart Association journal.

13 Dec 2022

Study uncovers a new immune culprit in Alzheimer’s disease

The reason your three-pound brain doesn't feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord.

13 Dec 2022

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

In a recent study posted to bioRxiv*, researchers in the United States assessed the impact of metabolic diseases on coronavirus disease 2019 (COVID-19) vaccine immunogenicity in a mouse model.

13 Dec 2022

Mediterranean diet may be a non-intrusive and affordable strategy to overcome infertility

With an emphasis on fruits, vegetables and legumes, the Mediterranean diet has long been applauded for its multiple health benefits. Now, new research shows that it may also help overcome infertility, making it a non-intrusive and affordable strategy for couples trying to conceive.

13 Dec 2022

Study finds spike in endocarditis among patients with cocaine or opioid use disorder from 2011 to 2022

The incidence rate of infective endocarditis - a rare but often fatal inflammation of the heart valves - among patients with cocaine use disorder or opioid use disorder increased from 2011 to 2022, with the steepest increase occurring from 2021 to 2022, a new study reports.

13 Dec 2022

Study suggests persistent inflammatory response triggered by SARS-CoV-2 may be responsible for observed sequelae in PASC patients

Researchers assessed the association of enhanced migratory or activated CD8+ T cell and reduced avidity reactive cellular response due to post-acute COVID-19 syndrome (PASC).

13 Dec 2022

Severe COVID-19 causes aging-like changes in the human brain

Severe COVID-19 triggers aging-like changes in the brain's frontal cortex region that results in cognitive deficits.

11 Dec 2022

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma.

9 Dec 2022

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points.

9 Dec 2022

Hospital financial decisions play a role in the critical shortage of pediatric beds for RSV patients

The dire shortage of pediatric hospital beds plaguing the nation this fall is a byproduct of financial decisions made by hospitals over the past decade, as they shuttered children's wards, which often operate in the red, and expanded the number of beds available for more profitable endeavors like joint replacements and cancer care.

9 Dec 2022

Inflammation News and Research

Subcutaneous fat protects against brain inflammation in females

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Study seeks to look for a better treatment for endometriosis

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Bad cholesterol and high blood pressure may be associated with higher risk of cardiovascular disease

Study uncovers a new immune culprit in Alzheimer’s disease

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

Mediterranean diet may be a non-intrusive and affordable strategy to overcome infertility

Study finds spike in endocarditis among patients with cocaine or opioid use disorder from 2011 to 2022

Study suggests persistent inflammatory response triggered by SARS-CoV-2 may be responsible for observed sequelae in PASC patients

Severe COVID-19 causes aging-like changes in the human brain

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Hospital financial decisions play a role in the critical shortage of pediatric beds for RSV patients

Microbiomes in female reproductive tract linked to pregnancy following use of ART

UH researchers investigate how traumatic experiences affect mental and physical health of migrants

Estrogen replacement therapy may be a tool to mitigate delirium

For patients with sickle cell disease, fertility care is about reproductive justice

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Low-intensity ultrasound therapies may help rebuild stronger knees

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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