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JAK inhibitors may be first effective treatment for people with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata—an autoimmune disease that causes patchy, and less frequently, total hair loss—had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

22 Sep 2016

Novel immunotherapy shows promise against AML in clinical trial

A new type of immunotherapy shows promise against cases of acute myeloid leukemia (AML) that recur after treatment or that never respond to therapy in the first place.

21 Sep 2016

New mobile health app may help manage hydroxyurea treatments in sickle cell patients

The National Heart, Lung, and Blood Institute, part of the National Institutes of Health, has awarded a 6-year, $4.4 million grant to St. Jude Children's Research Hospital and collaborators to improve the use of prescribed medication by sickle cell patients.

21 Sep 2016

Sanger Institute partners with St. Jude to support discovery, understanding of genetic mutations in paediatric cancers

The Wellcome Trust Sanger Institute is combining the power of COSMIC, its large-scale cancer genetics database, with ProteinPaint data mining and visualization system at St. Jude Children’s Research Hospital in Memphis TN, to support the discovery and understanding of genetic mutations in paediatric cancers.

21 Sep 2016

Study finds link between gut flora and fat distribution in children and teenagers

Children and teenagers who are obese have different microorganisms living in the digestive tract than their lean counterparts, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Sep 2016

Predominance of testosterone in males may explain disparate ACL injury rate between men and women

In studies on rats, Johns Hopkins Medicine scientists report new evidence that the predominance of the hormone testosterone in males may explain why women are up to 10 times more likely than men to injure the anterior cruciate ligament (ACL) in their knees.

20 Sep 2016

Exposure to EDCs may reduce vitamin D levels in the bloodstream

Exposure to bisphenol A (BPA) and other endocrine-disrupting chemicals (EDCs) may reduce levels of vitamin D in the bloodstream, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

20 Sep 2016

$New therapy for osteoporosis provides protection against bone fractures in postmenopausal women$

New therapy for osteoporosis provides protection against bone fractures in postmenopausal women

A recent analysis of results from a randomized controlled clinical trial indicates that abaloparatide-SC, a novel therapy for osteoporosis, provides consistent protection against bone fractures in postmenopausal women with osteoporosis regardless of their baseline bone density, age, and previous history of fracture.

19 Sep 2016

FDA authorizes marketing of new Aera system to treat patients with chronic ETD symptoms

The U.S. Food and Drug Administration today permitted marketing of a device that uses a small balloon to treat persistent Eustachian tube dysfunction (ETD), a condition in which pressure, pain or clogged or muffled sensations occur in the ear.

16 Sep 2016

New research seeks to find most effective medication for preventing life-threatening clots

Every year in the United States, thousands of high-risk fracture patients who have been admitted to trauma centers will suffer life-threatening blood clots related to the fracture. In rare cases these clots can even travel to the lungs, where they can cause sudden death.

16 Sep 2016

UTSW surgeons remove acoustic neuromas through small incisions in the ear canals

A surgical team at UT Southwestern Medical Center is helping to pioneer a new minimally invasive procedure that extracts vertigo-inducing tumors from the inner ear without having to remove a large piece of skull, as is usually required.

15 Sep 2016

Real-time MRI guidance could help target and deliver stem cell therapies

Working with animals, a team of scientists reports it has delivered stem cells to the brain with unprecedented precision by threading a catheter through an artery and infusing the cells under real-time MRI guidance.

14 Sep 2016

Discovery of immune antibody could lead to development of improved influenza vaccines

Dana-Farber Cancer Institute investigators report they have discovered a type of immune antibody that can rapidly evolve to neutralize a wide array of influenza virus strains - including those the body hasn't yet encountered.

14 Sep 2016

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Researchers at the Institute of Biomedical Research of Bellvitge, led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction in recurrences and metastases in breast cancer in a mouse animal model.

13 Sep 2016

Philips unveils innovative interventional oncology solution for liver cancer treatment at CIRSE 2016

Royal Philips today announced that it will unveil its latest innovation in interventional oncology at the 2016 Cardiovascular and Interventional Radiological Society of Europe annual meeting (CIRSE 2016), which will be held in Barcelona (Spain) from September 10 until 14.

13 Sep 2016

Revolutionary new scanning technique creates 3D images of bones with unparalleled resolution

Chemists from Trinity College Dublin in collaboration with RCSI have devised a revolutionary new scanning technique that produces extremely high-res 3D images of bones -- without exposing patients to X-ray radiation.

13 Sep 2016

BUAP researchers develop biomaterial that can be printed in 3D for regenerating bone tissue

Researchers at the Autonomous University of Puebla (BUAP) developed a biomaterial with the ability to serve as a support for regenerating bone tissue, which is biodegradable and can be printed in 3D with controlled porosity.

13 Sep 2016

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass.

9 Sep 2016

Female triathletes suffer from high rate of stress urinary and anal incontinence, study finds

A study led by Loyola Medicine researchers found that female triathletes are at higher risk for pelvic floor disorders, among other health issues.

9 Sep 2016

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy.

9 Sep 2016

Bone News and Research

JAK inhibitors may be first effective treatment for people with alopecia areata

Novel immunotherapy shows promise against AML in clinical trial

New mobile health app may help manage hydroxyurea treatments in sickle cell patients

Sanger Institute partners with St. Jude to support discovery, understanding of genetic mutations in paediatric cancers

Study finds link between gut flora and fat distribution in children and teenagers

Predominance of testosterone in males may explain disparate ACL injury rate between men and women

Exposure to EDCs may reduce vitamin D levels in the bloodstream

New therapy for osteoporosis provides protection against bone fractures in postmenopausal women

FDA authorizes marketing of new Aera system to treat patients with chronic ETD symptoms

New research seeks to find most effective medication for preventing life-threatening clots

UTSW surgeons remove acoustic neuromas through small incisions in the ear canals

Real-time MRI guidance could help target and deliver stem cell therapies

Discovery of immune antibody could lead to development of improved influenza vaccines

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Philips unveils innovative interventional oncology solution for liver cancer treatment at CIRSE 2016

Revolutionary new scanning technique creates 3D images of bones with unparalleled resolution

BUAP researchers develop biomaterial that can be printed in 3D for regenerating bone tissue

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Female triathletes suffer from high rate of stress urinary and anal incontinence, study finds

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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