Chromosome 8 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 8, one copy inherited from each parent, form one of the pairs. Chromosome 8 spans about 146 million DNA building blocks (base pairs) and represents between 4.5 percent and 5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 8 likely contains between 700 and 1,100 genes.

Genes on chromosome 8 are among the estimated 20,000 to 25,000 total genes in the human genome.

Role of host gene variants in COVID-19 severity

A new study discusses the importance of common, rare, and intermediate variants of several host genes to the clinical severity of infection with SARS-CoV-2.

20 Sep 2021

Researcher explores the genetic interplay between personality traits and COVID

In a recent study, scientists aimed to find the genetic effects that the coronavirus disease 2019 (COVID-19) has on individuals with psychiatric disorders.

19 Sep 2021

Sex defining factors influence expression of ACE2 and other SARS-CoV-2 machinery

Results from this study provided evidence for the hypothesis that sex-defining factors influence the expression of ACE2 and other SARS CoV-2 machinery.

17 Sep 2021

Albert Einstein College of Medicine receives $5 million NIH grant for IDD research

Albert Einstein College of Medicine has received a five-year, $5 million grant from the National Institutes of Health to support the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center, which has been at the forefront of research on normal and abnormal brain development for more than 50 years.

15 Sep 2021

Scientists identify a possible “Achilles’ heel” in the frustration of amyloid beta peptides

Progress on treating Alzheimer's disease has been frustratingly slow. A group of scientists in Houston suggest frustration at a very small scale may lead to a new path toward treatment.

14 Sep 2021

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Oncotarget published "Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells" which reported that this assay is based on the use of two isogenic HT1080 cell lines, one carrying a linear HAC and the other carrying a circular HAC.

6 Sep 2021

Researchers develop a machine learning-based screening tool for genetic syndromes in children

With an average accuracy of 88%, a deep learning technology offers rapid genetic screening that could accelerate the diagnosis of genetic syndromes, recommending further investigation or referral to a specialist in seconds, according to a study published in The Lancet Digital Health.

2 Sep 2021

Growing wheat varieties with biological nitrification inhibition trait could increase yields

An international collaboration has discovered and transferred to elite wheat varieties a wild-grass chromosome segment that causes roots to secrete natural inhibitors of nitrification, offering a way to dial back on heavy fertilizer use for wheat and to reduce the crop's nitrogen leakage into waterways and air, while maintaining or raising its productivity and grain quality, says a new report in the Proceedings of the National Academy of Sciences of the United States of America.

2 Sep 2021

Uppsala researchers find solution to long-standing biological search enigma

How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university have now discovered the solution; it is easier to find a rope than a ball if you are blindfolded.

1 Sep 2021

New, one-stop method developed to avoid de novo genetic disease in embryos

De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have.

31 Aug 2021

Research offers new insight into how to treat endometriosis

Endometriosis is a painful, chronic condition in which tissue from the uterus inappropriately grows outside the uterus.

26 Aug 2021

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Eggs and sperm are special cells for many reasons, but one of the characteristics that sets them apart is that, unlike other human cells, which have two copies of 23 chromosomes, one from the mother and one from the father, these sex cells, or gametes, have only one.

25 Aug 2021

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

A study by Prof. LIN Qiang from the South China Sea Institute of Oceanology (SCSIO) of the Chinese Academy of Sciences and his collaborators from Singapore and Germany lifts the veil on seadragons' mysterious looks, and sheds light on a sex-determination locus shared by seadragons and alligator pipefish, both members of the Syngnathidae family.

22 Aug 2021

Study provides insight into fitness effects of genomic structural variants in natural populations

Molecular geneticists have known for about a decade that genomic structural variants can play important roles in the adaptation and speciation of both plants and animals, but their overall influence on the fitness of plant populations is poorly understood.

16 Aug 2021

Chromosome 8 News and Research

Role of host gene variants in COVID-19 severity

Researcher explores the genetic interplay between personality traits and COVID

Sex defining factors influence expression of ACE2 and other SARS-CoV-2 machinery

Albert Einstein College of Medicine receives $5 million NIH grant for IDD research

Scientists identify a possible “Achilles’ heel” in the frustration of amyloid beta peptides

Cancer treatment with terpyridine platinum compounds induces telomere dysfunction, chromosome instability

Researchers develop a machine learning-based screening tool for genetic syndromes in children

Growing wheat varieties with biological nitrification inhibition trait could increase yields

Uppsala researchers find solution to long-standing biological search enigma

New, one-stop method developed to avoid de novo genetic disease in embryos

Research offers new insight into how to treat endometriosis

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Analysis of seadragon genome offers new insights into its phenotype and sex-determination locus

Study provides insight into fitness effects of genomic structural variants in natural populations

Structure of BRCA2 protein complex critical for DNA repair solved

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

SMC protein complex plays a decisive role in the dynamics of holocentromeres

Researchers identify genetic markers linked to COVID-19 severity and susceptibility

Study offers genetic insights into the underlying biology of reproductive aging

Researchers solve century old mystery by identifying how sex cells get the right genetic mix

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