Estradiol News and Research

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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Bionovo announces publication of positive trial results for Menerba

Bionovo, Inc. has announced the online publication of a peer-reviewed article in the journal, Menopause, reporting Menerba (formerly MF101) is well tolerated, safe and effective for the treatment of vasomotor symptoms (hot flashes and night sweats) associated with menopause.

3 Mar 2009

Pregnancy-related hormonal changes linked to increased risk of restless legs syndrome

A study in the Feb. 1 issue of the journal Sleep shows that the elevation in estradiol levels that occurs during pregnancy is more pronounced in pregnant women with restless legs syndrome (RLS) than in controls.

2 Feb 2009

Hormones make pretty women serial monogamists

American researchers say women with high levels of estrogen feel more attractive and are far more likely to indulge in affairs.

18 Jan 2009

Scientists visualize the mechanism of synthesizing estrogen

The molecular details of Aromatase, the key enzyme required for the body to make estrogen, are no longer a mystery thanks to the structural biology work done by the Ghosh lab at the Hauptman-Woodward Medical Research Institute (HWI) in Buffalo, New York.

7 Jan 2009

Watson Pharmaceuticals receives FDA approval for generic Mircette

Watson Pharmaceuticals, Inc. has received final approval from the United States Food and Drug Administration on its Abbreviated New Drug Application (ANDA) for desogestrel/ethinyl estradiol and ethinyl estradiol tablets USP, 0.15 mg / 0.02 mg.

30 Dec 2008

Azur Pharma to acquire U.S. rights to Elestrin

Azur Pharma Limited has announced that it has entered into a definitive agreement with BioSante Pharmaceuticals, Inc to acquire U.S. rights to Elestrin.

8 Dec 2008

Sex hormones may affect atherosclerosis

Naturally produced sex hormones may influence the risk and progression of atherosclerosis, or hardening of the arteries, Johns Hopkins researchers report in a recent study.

11 Nov 2008

Sun-damaged skin does not improve with estrogen treatments

Treating the skin with estrogen can stimulate collagen production-which improves the appearance of the skin-in areas not typically exposed to the sun, according to new research from the University of Michigan Health System.

15 Sep 2008

Sex hormones link to heart risk

Men are more prone to - and likely to die of - heart disease compared with women of a similar age - and sex hormones are to blame, according to a new University of Leicester led study.

1 Sep 2008

Oestrogen - a beneficial addition to treatment of schizophrenia in women

Australian scientists have found that women suffering from schizophrenia were less likely to suffer hallucinations or delusions, when the hormone oestrogen was added to their treatment.

4 Aug 2008

Chronic exposure to estrogen impairs some cognitive functions

University of Illinois researchers report this week that chronic exposure to estradiol, the main estrogen in the body, diminishes some cognitive functions. Rats exposed to a steady dose of estradiol were impaired on tasks involving working memory and response inhibition, the researchers found.

3 Aug 2008

Sleep and menopause

Difficulty falling asleep and staying asleep increase as women go through menopause according to research by Rush University Medical Center. Waking up earlier than planned also increases through late perimenopause but decreases when women become postmenopausal. The study is published in the July 1 issue of the journal SLEEP.

1 Jul 2008

Barr and Bayer sign agreements for launch of generic Yasmin and Yaz oral contraceptives

Barr Laboratories, Inc. has entered into supply and licensing agreements with Bayer for generic versions of Bayer's Yasmin (drospirenone and ethinyl estradiol) and Yaz (drospirenone and ethinyl estradiol) oral contraceptive products.

24 Jun 2008

EntreMed receives new patent for 2-Methoxyestradiol analogs

EntreMed, Inc. has announced the issuance of U.S. Patent No. 7,371,741 covering analogs of 2- methoxyestradiol (2ME2).

11 Jun 2008

Flow of potassium ions in brain cells is key to sexual arousal

When it comes to sex, a female rat knows how to avoid a communication breakdown. To announce her sexual readiness, she will automatically arch her back, deflect her tail and stand rigid to allow an aroused male to mount.

3 Jun 2008

Barr announces approval of generic version of Yasmin (drospirenone and ethinyl estradiol)

Barr Pharmaceuticals, Inc. has announced that its subsidiary, Barr Laboratories, Inc., has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) to manufacture and market a generic version of Yasmin (drospirenone and ethinyl estradiol), an oral contraceptive product manufactured and marketed by Bayer Schering Pharma, AG.

9 May 2008

Oestrogen works for women the way testosterone does for men

Collaboration by American and German scientists has revealed that the sex hormone oestrogen increases a women's competitiveness.

5 May 2008

Breastfeeding during anti-epilepsy drug treatment does not appear to harm a child's cognitive development

A first of its kind study finds breastfeeding while taking certain seizure medications does not appear to harm a child's cognitive development. The research will be presented at the upcoming American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008.

17 Apr 2008

Watson Pharmaceuticals files application for generic LYBREL

Watson Pharmaceuticals, Inc. has confirmed that it has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market its Levonorgestrel and Ethinyl Estradiol tablets, USP (0.09 mg/0.02 mg) extended-cycle oral contraceptive product prior to the expiration of patents owned by Wyeth.

14 Mar 2008

Long-term effects of synthetic progestins cause for concern

The widely used synthetic progestin medroxyprogesterone acetate (MPA) decreased endothelial function in premenopausal women in a study done at the University of Oregon.

11 Mar 2008