Exhaustion News and Research

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Exponential rise in COVID-19 hospitalization risk with age due to waning T cell immunity

The age-related increase in the risk of severe disease and death from COVID-19 mirrors earlier patterns seen with infections. Such trends may help understand the mechanisms underlying the clinical feature. A recent study published in the preprint server medRxiv* in August 2020 shows the effect of age and sex on COVID-19 hospitalization rates in the USA and helps understand how immune function is involved in this pandemic.

2 Sep 2020

Public health officials are our COVID commanders. Treat them with respect.

As a veteran who served back-to-back tours in Iraq, I initially cringed when commentators compared the COVID-19 crisis to wartime — no bullets, no blood and no one volunteered for this.

1 Sep 2020

Study reveals emotional exhaustion of nurses providing pediatric cardiology care

A survey of nurses caring for children with heart problems has revealed that more than half are emotionally exhausted.

28 Aug 2020

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

Melbourne researchers have identified mechanisms leading to the functional deterioration of the immune system in response to severe viral infections, such as HIV or COVID-19.

24 Aug 2020

ARDS may not be the primary lung iInjury in COVID-19

A new Italian study published on the preprint server medRxiv in August 2020 shows that this may not be an adequate explanation, since ARDS is a nonspecific diagnosis. Instead, they say, antemortem lung biopsy shows a “Covid pattern” of acute lung injury, which could guide the application of therapeutics.

16 Aug 2020

COVID-19 pandemic as severe as 1918 influenza pandemic

A recent study published in the journal JAMA Network Open reveals that the excess death toll observed during the initial period of coronavirus disease 2019 (COVID-19) pandemic in New York City is comparable to that observed during the peak of the H1N1 influenza pandemic in 1918.

14 Aug 2020

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

Organocatalysts consisting of organic compounds without metal elements are receiving much attention as next generation catalysts in the hope of reducing environmental burden and coping with exhaustion/rising prices of rare metals.

12 Aug 2020

Majority of trainee GPs willing to use mindfulness to reduce burnout, study shows

Mindfulness could help trainee GPs to build their resilience and reduce burnout, helping to reduce the number of newly qualified GPs leaving the profession, according to University of Warwick researchers.

3 Aug 2020

Hollings Cancer Center researcher receives NCI grants for cancer immunotherapy studies

Hollings Cancer Center researcher Jessica Thaxton, Ph.D., is the recipient of two grants totaling $3.4 million from the National Cancer Institute for her work in cancer immunotherapy and cell stress, one of which is part of the Cancer Moonshot Initiative on immunometabolism.

23 Jul 2020

Study highlights the impact of gambling on partners and families

With the lure of online gambling high during COVID-19 lockdowns - and some gambling venues now reopening - partners and families of problem gamblers may be the first to see a problem emerging.

22 Jul 2020

Study assesses the stress levels of U.S. physicians during COVID-19 pandemic

Amid the COVID-19 chaos in many hospitals, emergency medicine physicians in seven cities around the country experienced rising levels of anxiety and emotional exhaustion, regardless of the intensity of the local surge, according to a new analysis led by UC San Francisco.

21 Jul 2020

A multi-omics single cell analysis on COVID-19

Now, a new study published on the preprint server medRxiv aims to analyze the immune response over time, using multi-omics in the study of a single cell.

21 Jul 2020

Buck researchers investigate ketone bodies as possible therapeutic against COVID-19

Given the disproportionate impact that COVID-19 has on older adults in terms of death and lasting disability, and the impact of common aging-related comorbidities like diabetes and cardiovascular disease, Buck Institute professor and practicing geriatrician John Newman, MD, PhD, can make a compelling argument that those infected with the SARS-CoV2 virus are suffering from an aging-related disease, no matter how old they are when they get infected.

15 Jul 2020

Dysfunctional T cells present at high levels in severe COVID-19

Now, a new study by researchers at Saarland University, Germany, and published on the preprint server medRxiv in July 2020 shows that there are higher levels of anti-SARS-CoV-2 T cells, which show significant alterations in the phenotype and function.

12 Jul 2020

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

The ongoing COVID-19 pandemic has cost hundreds of thousands of human lives, besides more than 11 million cases. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the disease was initially thought to be more severe in the elderly and those with pre-existing medical conditions. However, it started to manifest in children after the peak of the first wave.

7 Jul 2020

Exhaustion News and Research

Exponential rise in COVID-19 hospitalization risk with age due to waning T cell immunity

Public health officials are our COVID commanders. Treat them with respect.

Study reveals emotional exhaustion of nurses providing pediatric cardiology care

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

ARDS may not be the primary lung iInjury in COVID-19

COVID-19 pandemic as severe as 1918 influenza pandemic

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

Majority of trainee GPs willing to use mindfulness to reduce burnout, study shows

Hollings Cancer Center researcher receives NCI grants for cancer immunotherapy studies

Study highlights the impact of gambling on partners and families

Study assesses the stress levels of U.S. physicians during COVID-19 pandemic

A multi-omics single cell analysis on COVID-19

Buck researchers investigate ketone bodies as possible therapeutic against COVID-19

Dysfunctional T cells present at high levels in severe COVID-19

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

Migrant workers contribute to the spread of COVID-19 in India’s villages

Cities brace for ‘collision course’ of heat waves and COVID-19

New study to analyze risks posed by heat wave and COVID-19

Early intensive treatment of rheumatoid arthritis offers an opportunity to manage fatigue

Damon Runyon Cancer Research Foundation awards $3.2 million to early-career physician-scientists

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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