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Increased paternal age may give rise to disease in the new generation

In a new study, researchers assessed the effects of paternal age on novel mutations and diseases in the next generation.

8 Nov 2022

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Researchers identified a genetic association signal, via genome-wide association studies, between severe COVID-19 with systemic lupus erythematosus, an autoimmune disease.

7 Nov 2022

Study shows likely SARS-CoV-2 transmission between different rooms of a quarantine hotel

The results of this study, published in the Emerging Infectious Diseases journal, underline the enhanced transmissibility of the Omicron variants of the virus, which takes advantage of small airstreams to jump to new hosts. "Our findings emphasize the importance of ventilation and integrity of building structure in quarantine facilities."

6 Nov 2022

Whole-genome sequencing is a more comprehensive prenatal test l BGI Perspectives

BGI-Research and the Maternal and Child Health Hospital of Hubei Province (MCHH) published whole-genome sequencing research results in npj Genomic Medicine.

From BGI Genomics 3 Nov 2022

Research reveals how whole-genome sequencing may enhance detection of fetal CNS anomalies

BGI-Research and the Maternal and Child Health Hospital of Hubei Province (MCHH) published whole-genome sequencing research results in npj Genomic Medicine.

3 Nov 2022

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

In a recent study posted to the medRxiv* preprint server, researchers in the United States investigated the source of an enigmatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)-like spike (S) protein strain detected in wastewater but not in clinical samples.

2 Nov 2022

The epigenetic alterations of monocytes in severe COVID-19

Researchers performed DNA methylation analysis on monocytes in the peripheral blood samples obtained from severe COVID-19 patients.

28 Oct 2022

Advanced type of nanoparticle could help fight hard-to-treat cancers

Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers.

27 Oct 2022

First report of natural recombination of monkeypox virus genome

Researchers analyzed monkeypox virus sequences during the current 2022 outbreak to investigate whether MPXV is adapting for improved survival and viral transmission among humans.

27 Oct 2022

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

In a new study, researchers investigated whether low-complexity regions (LCRs) were more accountable for the current 2022 IIb clade monkeypox (MPX) virus (MPXV) outbreak rather than single-nucleotide polymorphisms (SNPs).

24 Oct 2022

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

Dog ownership during infancy might attenuate the risk of persistent wheezing

In a new study, researchers examined the gene-environment (GxE) interactions between pet ownership in infancy and the 17q12-21 (asthma-risk) locus concerning wheezing.

24 Oct 2022

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Researchers examined the role of epigenetic modifications of the host cell gene expression in determining the pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and explored the use of vitamin D as a therapeutic agent against coronavirus disease 2019 (COVID-19).

19 Oct 2022

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

In a new study, researchers pursued direct-acting severe acute respiratory syndrome coronavirus-2 drugs that compete for nucleotide-binding pockets (NBPs) of SARS-CoV-2 proteins.

11 Oct 2022

Nucleotide News and Research

Increased paternal age may give rise to disease in the new generation

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Study shows likely SARS-CoV-2 transmission between different rooms of a quarantine hotel

Whole-genome sequencing is a more comprehensive prenatal test l BGI Perspectives

Research reveals how whole-genome sequencing may enhance detection of fetal CNS anomalies

Scientists identify a cryptic SARS-CoV-2 lineage in wastewater

The epigenetic alterations of monocytes in severe COVID-19

Advanced type of nanoparticle could help fight hard-to-treat cancers

First report of natural recombination of monkeypox virus genome

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

Dog ownership during infancy might attenuate the risk of persistent wheezing

Exploring epigenetic modifications and the use of vitamin D therapy in COVID-19

Scientists develop a pseudovirus system to deep mutational scan the full SARS-CoV-2 spike

Study identifies genetic variation that influences lithium-induced neural proliferation

Scientists use enhanced environmental surveillance for poliovirus type 2 detection in London sewage samples

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

Novel method deploys nanopore tweezers to facilitate inhibition of SARS-CoV-2 helicase at single-nucleotide resolution

Researchers report the first RT-qPCR for simultaneous detection and discrimination of Omicron sub-variants

Researchers explore drug-repurposing candidates acting against nucleotide-binding pockets of multiple SARS-CoV-2 proteins

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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