Clinical Trial News and Research

RSS

New method of guidance for heart bypass surgery to be tested on patients for the first time

A new approach to the guidance, planning and conducting of heart bypass surgery is being tested on patients for the first time in a clinical trial coordinated by a high-level research team at NUI Galway.

25 Nov 2020

Iron infusion highly effective to treat anemia in low-income settings

Over 1 billion people globally are affected by iron-deficiency anemia. In sub-Saharan Africa, anemia is a major public health concern with roughly 60% of the population suffering from anemia.

25 Nov 2020

Dexamethasone use could reduce immune checkpoint inhibitor efficacy in glioblastoma patients

Bottom Line: Among patients with glioblastoma receiving an immune checkpoint inhibitor, those who received the corticosteroid dexamethasone at baseline for cerebral edema had significantly worse overall survival.

25 Nov 2020

Channeling the immune system to combat head and neck cancer

University of Cincinnati researchers have discovered new clues into why some people with head and neck cancer respond to immunotherapy, while others don't.

24 Nov 2020

Largest clinical trial launched to treat mild-to-moderate COVID-19 patients in Africa

Thirteen African countries and an international network of research institutions have joined forces to launch the largest COVID-19 clinical trial in mild-to-moderate outpatients in Africa.

24 Nov 2020

New legal push aims to speed magic mushrooms to dying patients

Back in March, just as anxiety over COVID-19 began spreading across the U.S., Erinn Baldeschwiler of La Conner, Washington, found herself facing her own private dread.

24 Nov 2020

Study: 58% of adults over 50 are willing to receive COVID-19 vaccination

Once enough people receive effective vaccines against the novel coronavirus, experts say, the end of the pandemic may be in sight. But a new poll of older adults - one of the highest-priority groups for vaccination - suggests an uphill climb lies ahead to reach that goal.

24 Nov 2020

Avacta Group announces significant progress in the development of SARS-CoV-2 rapid antigen test

Avacta Group plc, the developer of innovative cancer therapies and diagnostics based on its proprietary Affimer® and pre|CISION™ platforms, is pleased to announce significant progress in the development of a highly scalable manufacturing process for a lateral flow SARS-CoV-2 antigen test being carried out with BBI Solutions, and that the lateral flow test has very good analytical sensitivity with laboratory samples.

From Avacta Life Sciences Ltd. 24 Nov 2020

Researchers assess benefits of magnetic seizure therapy to treat depression in bipolar patients

Researchers are assessing whether magnetic seizure therapy (MST) can help relieve treatment-resistant depression in bipolar patients in a clinical trial led by The University of Texas Health Science Center at Houston (UTHealth).

24 Nov 2020

Researchers are working on new project to develop brain implant for blind people

Implanting a device into the brain to generate a rough perception of sight for people with blindness may sound like the stuff of science fiction, but researchers from The University of Texas at Dallas and partner institutions aim to make that vision a reality.

23 Nov 2020

Marinomed to initiate clinical trial with Carragelose for preventing COVID19 in frontline healthcare staff

Marinomed Biotech AG, a globally operating biopharmaceutical company, announced today plans to initiate a Phase IV clinical trial with Carragelose (iota-carrageenan).

23 Nov 2020

First checkpoint inhibitor vaccine shown to be safe, effective in colon cancer animal model

A study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute described a potential therapeutic anticancer vaccine that frees suppressed cancer-killing immune cells, enabling them to attack and destroy a tumor.

23 Nov 2020

FDA expands approved indication for influenza treatment to include post-exposure prevention

Today, the U.S. Food and Drug Administration expanded the approved indication for Xofluza (baloxavir marboxil) to include post-exposure prevention of influenza (flu) for patients 12 years of age and older after contact with an individual who has the flu.

23 Nov 2020

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for casirivimab and imdevimab to be administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) with positive results of direct SARS-CoV-2 viral testing and who are at high risk for progressing to severe COVID-19.

23 Nov 2020

Analysis shows social distancing helped reduce nosocomial SARS-CoV-2 transmission in London

Recently, a team of researchers from the King's College London, Guy's and St Thomas' NHS Foundation Trust, and St Thomas' Hospital, London analyzed comprehensive epidemiological and viral nanopore sequence data from 574 patients with SARS-CoV-2 infection confirmed by a PCR test in March 2020.

22 Nov 2020

Sinovac Biotech's COVID-19 vaccine candidate triggers immune response

Now, Sinovac Biotech's candidate vaccine, CoronaVac, has been found to induce an immune response in healthy adults aged 18–59 years, 28 days post-vaccination. However, the level of antibodies generated was lower than in people who had recovered from the illness.

19 Nov 2020

Hyperbaric oxygen treatments in healthy adults can reverse the aging process, finds study

A new study from Tel Aviv University and the Shamir Medical Center in Israel indicates that hyperbaric oxygen treatments (HBOT) in healthy aging adults can stop the aging of blood cells and reverse the aging process.

19 Nov 2020

New combination treatment for recurrent ovarian cancer shows positive outcomes

A team from Roswell Park Comprehensive Cancer Center has detailed striking findings on the effectiveness of a previously untried combination of old and new drugs as treatment for recurrent ovarian cancer.

19 Nov 2020

NIH-funded study to test emergency treatment for devastating stroke in Memphis

The University of Tennessee Health Science Center's Stroke Team is joining researchers from more than 100 hospitals worldwide to conduct a National Institutes of Health (NIH)-funded research study called FASTEST that will test the safety and efficacy of a medication called recombinant factor Vlla to prevent hemorrhage expansion in patients with strokes caused by bleeding in the brain - intracerebral hemorrhage strokes.

19 Nov 2020

New findings support current and planned clinical trials of Janssen SARS-CoV-2 vaccine

Researchers from the United States and The Netherlands have conducted a pre-clinical study supporting the initiation of a Phase 3 trial to test a two-dose regimen of the Janssen Ad26.COV2.S vaccine candidate among adult and elderly individuals.

19 Nov 2020

Clinical Trial News and Research

New method of guidance for heart bypass surgery to be tested on patients for the first time

Iron infusion highly effective to treat anemia in low-income settings

Dexamethasone use could reduce immune checkpoint inhibitor efficacy in glioblastoma patients

Channeling the immune system to combat head and neck cancer

Largest clinical trial launched to treat mild-to-moderate COVID-19 patients in Africa

New legal push aims to speed magic mushrooms to dying patients

Study: 58% of adults over 50 are willing to receive COVID-19 vaccination

Avacta Group announces significant progress in the development of SARS-CoV-2 rapid antigen test

Researchers assess benefits of magnetic seizure therapy to treat depression in bipolar patients

Researchers are working on new project to develop brain implant for blind people

Marinomed to initiate clinical trial with Carragelose for preventing COVID19 in frontline healthcare staff

First checkpoint inhibitor vaccine shown to be safe, effective in colon cancer animal model

FDA expands approved indication for influenza treatment to include post-exposure prevention

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Analysis shows social distancing helped reduce nosocomial SARS-CoV-2 transmission in London

Sinovac Biotech's COVID-19 vaccine candidate triggers immune response

Hyperbaric oxygen treatments in healthy adults can reverse the aging process, finds study

New combination treatment for recurrent ovarian cancer shows positive outcomes

NIH-funded study to test emergency treatment for devastating stroke in Memphis

New findings support current and planned clinical trials of Janssen SARS-CoV-2 vaccine

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer