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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Study explains why moles can change into melanoma

Moles and melanomas are both skin tumors that come from the same cell called melanocytes. The difference is that moles are usually harmless, while melanomas are cancerous and often deadly without treatment.

23 Nov 2021

New virtual reality platform could revolutionize the way single-cell omics data is analyzed

Science has the technology to measure the activity of every gene within a single individual cell, and just one experiment can generate thousands of cells worth of data.

23 Nov 2021

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

A new study, published on the bioRxiv* preprint server, has discovered a class of new immunostimulatory RNAs while studying influenza infection-associated host genes in human lung epithelial cells using small interfering RNAs (siRNAs). Scientists revealed that these short duplex RNAs could induce type I and type III interferons (IFN-I/III) in a wide variety of cells.

23 Nov 2021

A novel reverse epitope discovery approach to characterize SARS-CoV-2 public CD4+ αβ T cell clonotypes

A new study, published on the bioRxiv* preprint server, has focused on public clonotypes, i.e., clones found in multiple individuals, for the development of a novel reverse epitope discovery technique. This technique holds greater potential for population-wide applications.

23 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Researchers synthesize carbon dots using different precursors and studied their antimicrobial effects in gram-negative bacteria.

22 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

In vertebrates, large exons often skip splicing events and are evolutionarily conserved. Scientists from Nagoya University, Japan, led by Associate Professor Akio Masuda, have recently identified the mechanism behind regulated splicing of large constitutive exons which are rich in disordered regions, and their potential involvement in the assembly of transcription factors.

21 Nov 2021

New study uncovers a mechanism of sleep in zebrafish

Why do humans spend a third of their lives sleeping? Why do animals sleep? Throughout evolution sleep has remained universal and essential to all organisms with a nervous system, including invertebrates such as flies, worms, and even jellyfish.

21 Nov 2021

Viral biomolecular condensation

A review published in PLOS Pathogens deconstructs virus condensation and provides a biochemical background for LLPS.

19 Nov 2021

Air filter and floor sampling to detect SARS-CoV-2 RNA in schools

A study recently published on the medRxiv* preprint server observed the presence of SARS-CoV-2 RNA in five schools (96 classrooms) in Davis, California (USA), by collecting weekly surface-swab samples from classroom floors and/or portable high-efficiency particulate air (HEPA) units.

18 Nov 2021

Study involving a rat model offers potential treatment for Alexander disease

Alexander disease is a progressive and rare neurological disorder with no cure or standard course of treatment. But a new study led by researchers at the University of Wisconsin–Madison involving a rat model of the disease offers a potential treatment for the typically fatal condition.

18 Nov 2021

New study highlights the important role of rare genomic differences in OCD risk

Both rare and commonly observed differences in the DNA letters strung along a person's chromosomes can explain about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD), according to a new study led by scientists at the Icahn School of Medicine at Mount Sinai.

18 Nov 2021

New insights on the link between CRISPR, p53 gene and mutated cancer cells

A protein that protects cells from DNA damage, p53, is activated during gene editing using the CRISPR technique.

18 Nov 2021

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

The new research findings help to understand mechanisms that lead to different types of intestinal tumors. They show that the Lef1 gene suppresses the development and growth of colorectal cancer by restricting the formation of cancer stem cell niches.

18 Nov 2021

Experts debate whether whole genome sequencing is necessary for all newborn babies

Genomics England, a government owned company, recently announced a pilot programme of whole genome sequencing to screen for genetic diseases in 200,000 healthy seeming newborns.

18 Nov 2021

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Canadian public health researchers recently published a study in the journal Antiviral Research wherein they described generating a panel of murine hybridomas recognizing SARS-CoV-2 spike protein or nucleoprotein, capable of neutralizing the SARS-CoV-2 variants of concern, proving their therapeutic potential.

17 Nov 2021

Scientists use advanced microscopes to delve deeper into protein degradation process

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

17 Nov 2021

DNA News and Research

Further Reading

Experimental compound reduces diabetic complications in mice

Study explains why moles can change into melanoma

New virtual reality platform could revolutionize the way single-cell omics data is analyzed

Discovery of a broad-spectrum antiviral activity in self-assembling immunostimulatory duplex RNAs

A novel reverse epitope discovery approach to characterize SARS-CoV-2 public CD4+ αβ T cell clonotypes

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers identify mechanism behind regulation of large exon splicing during vertebrate evolution

New study uncovers a mechanism of sleep in zebrafish

Viral biomolecular condensation

Air filter and floor sampling to detect SARS-CoV-2 RNA in schools

Study involving a rat model offers potential treatment for Alexander disease

New study highlights the important role of rare genomic differences in OCD risk

New insights on the link between CRISPR, p53 gene and mutated cancer cells

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

Experts debate whether whole genome sequencing is necessary for all newborn babies

Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern

Scientists use advanced microscopes to delve deeper into protein degradation process

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