Genes News and Research

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Study indicates widespread SARS-CoV-2 exposure in wildlife

In a recent study posed to the bioRxiv* preprint server, researchers at Virginia Tech University investigated wildlife exposure to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).

8 Nov 2022

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Significant immunological differences between young men and women were shown to mediate sex differences in the responses to the virus that causes COVID-19, according to a collaborative study of nearly 3,000 young, healthy members of the U.S. Marine Corps.

8 Nov 2022

Scientists determine 5,072 essential human genes

In a recent study published in the journal Cell, researchers examined the phenotypic landscape of multiple elusive essential human genes to create a detailed genotype-phenotype resource outlining the phenotypic consequences of disrupting fundamental cellular processes.

8 Nov 2022

Protein complex may present strong therapeutic target for lethal breast cancer

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that a protein complex that governs gene expression (called CoREST) sometimes gets rewired during breast cancer to help estrogen receptor positive (ER+) tumors resist endocrine therapies and become more aggressive.

8 Nov 2022

Cell competition could be responsible for cancer relapses, study shows

A normal process called cell competition, in which healthy tissues eliminate unhealthy cells, could be responsible for cancer relapses in patients months or years after they were declared cancer-free, a new study by UT Southwestern Simmons Cancer Center researchers suggests.

8 Nov 2022

Terasaki Innovation Summit to focus on improving technological, entrepreneurial translation of personalized medicines

The Terasaki Institute for Biomedical Innovation (TIBI) will be hosting the Terasaki Innovation Summit on March 8-10, 2023, at the UCLA Meyer & Renee Luskin Center in Los Angeles.

8 Nov 2022

Genetic variant associated with slimness estimated to be present in almost 60% of the Europeans

How much do genes influence our body weight? For the general population this influence is around 20%, according to studies that in recent years have analyzed the complete genome of tens of thousands of people.

8 Nov 2022

Researchers unravel genetic changes in a region that controls the activity of the genome

Scientists have discovered the cause of a rare condition within a part of the genome that has been largely unexplored in medical genetics. A team at the University of Exeter has found genetic changes in a region that controls the activity of the genome, turning on or off genes, and in doing so they have found a key that could unlock other causes of rare conditions.

8 Nov 2022

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Non-compaction cardiomyopathy is a heart condition caused by defects that arise during fetal development and can have diverse health impacts in affected individuals, including sudden cardiac death.

7 Nov 2022

New analysis finds significant disparities in the treatment of familial hypercholesterolemia

The Family Heart Foundation, a leading research and advocacy organization, shared results from an analysis of its large U.S. Family Heart DatabaseTM showing significant disparities exist in the treatment of familial hypercholesterolemia (FH) among racial groups, and by income and education levels.

7 Nov 2022

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio states in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations.

7 Nov 2022

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

A genetic test known as chromosomal microarray analysis (CMA) could help identify the cause of sudden infant death syndrome (SIDS) or its counterpart in older children, known as sudden unexplained death in childhood (SUDC), finds a study led by Boston Children's Hospital.

7 Nov 2022

DNA barcoding shows how cancer cells evade the immune system's defenses

Some cancer cells can deploy parallel mechanisms to evade the immune system's defences as well as resist immunotherapy treatment, according to a new study from the Garvan Institute of Medical Research.

7 Nov 2022

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

A new study demonstrated transcriptomic dysregulation in the cerebral cortex in autism spectrum disorder (ASD).

7 Nov 2022

Scientists map neural pathways that lead to vomiting after eating contaminated food

A new study describes a system by which gut-brain pathways coordinate with brain circuits to initiate nausea and vomiting.

6 Nov 2022

HPV vaccine rates in Utah increase by more than 16% among young men and women, CDC data reveals

When life should have been ripe with possibilities, Mandy Murry instead faced a devastating diagnosis. Murry was diagnosed with cervical cancer when she was 22.

4 Nov 2022

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and - similar to COVID-19 - mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines in its mission to infect more people.

4 Nov 2022

Circadian disruption induces weight gain through changes in gut microbiota

In a recent study published in the journal Molecular Metabolism, researchers investigated the impact of environmental and genetic disruptions of the circadian rhythms on the peripheral circadian clock synchronization and microbiome oscillations in the gastrointestinal tract.

3 Nov 2022

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

A new study investigated the impact of a monoclonal anti-thymic stromal lymphopoietin (TSLP) antibody on subcutaneous allergen immunotherapy (SCIT) efficacy among patients with allergic rhinitis.

3 Nov 2022

Parental discord linked to children's genetic risk for alcohol problems

Parents can transmit a genetic risk for alcohol problems to their children not only directly, but also indirectly via genetically influenced aspects of the home environment, such as marital discord or divorce, according to a Rutgers researcher.

3 Nov 2022

Genes News and Research

Study indicates widespread SARS-CoV-2 exposure in wildlife

Study helps understand the basis of sex differences in SARS-CoV-2 infection

Scientists determine 5,072 essential human genes

Protein complex may present strong therapeutic target for lethal breast cancer

Cell competition could be responsible for cancer relapses, study shows

Terasaki Innovation Summit to focus on improving technological, entrepreneurial translation of personalized medicines

Genetic variant associated with slimness estimated to be present in almost 60% of the Europeans

Researchers unravel genetic changes in a region that controls the activity of the genome

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

New analysis finds significant disparities in the treatment of familial hypercholesterolemia

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

DNA barcoding shows how cancer cells evade the immune system's defenses

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

Scientists map neural pathways that lead to vomiting after eating contaminated food

HPV vaccine rates in Utah increase by more than 16% among young men and women, CDC data reveals

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Circadian disruption induces weight gain through changes in gut microbiota

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

Parental discord linked to children's genetic risk for alcohol problems

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