Therapeutics News and Research

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Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Findings of a new study led by Prof. XU Guowang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences and Prof. YANG Chunzhang from the National Cancer Institute shed light on the selective therapeutics for IDH1-mutated glioma by targeting glutathione synthesis pathway.

13 Apr 2020

Could DPP4 inhibitors help treat COVID-19?

Researchers and clinicians are scrambling to find ways to combat COVID-19, including new therapeutics and eventually a vaccine.

13 Apr 2020

Super-charging production of drugs for COVID-19

Researchers are ramping up production of a promising drug that has proven effective in obliterating SARS-CoV in cellular cultures. The team hopes that the drug might also be effective in the fight against SARS's close genetic cousin, the novel coronavirus (COVID-19).

13 Apr 2020

Molecular pathway responsible for TNBC's progression and spread identified

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer, a particularly aggressive form of the disease, less than 20% respond.

13 Apr 2020

FDA approves first-ever treatment for patients with inoperable plexiform neurofibromas

The U.S. Food and Drug Administration has approved Koselugo (selumetinib) for use in patients with inoperable plexiform neurofibromas, a common manifestation in the disease neurofibromatosis type one (NF1).

13 Apr 2020

Rockefeller and SNF announce $3 million expansion of partnership for COVID-19 research

The Rockefeller University and the Stavros Niarchos Foundation today announced a $3 million expansion of their longstanding partnership for research and medicine, bolstering Rockefeller's round-the-clock research initiatives related to COVID-19 and the SARS-CoV-2 virus that causes it.

13 Apr 2020

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

A team of researchers has come out with the first detailed map of the transcriptome and epitranscriptome of the virulent SARS-CoV-2 that causes COVID-19 disease, the illness that has become a pandemic ravaging both developed and less developed countries of the world. The study, published in the journal Cell in April 2020, may assist in the development of new vaccines and therapeutics.

12 Apr 2020

Hinge Therapeutics and TUT collaborate to advance drug discovery by ion imaging

Hinge Therapeutics is an early-stage biopharmaceutical company focused on developing small-molecule therapeutics against traditionally undruggable/challenging targets for unmet medical needs.

9 Apr 2020

Researchers identify COVID-19 drug lead treatments

An international team of researchers has tested more than 10,000 compounds to identify six drug candidates that may help treat COVID-19.

9 Apr 2020

Microneedle patches for potential COVID-19 vaccines or therapeutics

The COVID-19 pandemic is spreading over the world, causing panic and illness on a scale unprecedented in one hundred years. Even while the death toll nears 100,000, with over 1.5 million confirmed cases worldwide, public health experts and medical professionals are battling it using all the weapons available. Unfortunately, these are all too few.

9 Apr 2020

Combination of rare, damaging mutations negatively affects healthspan and longevity

Scientists report that the combined effects of rare, damaging mutations present at birth have a negative impact on healthspan and longevity, according to a study published this week in eLife.

9 Apr 2020

'Off-the-shelf' artificial cardiac patch improves heart attack recovery in rat and pig models

Researchers from North Carolina State University have developed an "off-the-shelf" artificial cardiac patch that can deliver cardiac cell-derived healing factors directly to the site of heart attack injury. In a rat model of heart attack, the freezable, cell-free patch improved recovery.

8 Apr 2020

Philadelphia Eagles owner contributes $1 million to Penn Medicine to fight COVID-19 pandemic

Philadelphia Eagles owner Jeffrey Lurie today announced a $1 million contribution to Penn Medicine to establish the COVID-19 Immunology Defense Fund, laying the foundation for the world's foremost experts to fight the novel coronavirus pandemic.

8 Apr 2020

Study compares health of pregnant and non-pregnant women with IBD

Inflammatory bowel disease--including Crohn's disease and ulcerative colitis--often affects women of childbearing age.

8 Apr 2020

Australian plant that produces antibodies may help in coronavirus vaccine production

As the world reels from the rising number of cases of COVID-19 disease caused by SARS-CoV-2, an Australian scientist, Prof. Peter Waterhouse from Laboratory of Molecular Genetics (LMG) at Queensland University of Technology (QUT), is working with a native plant from Australia that shows potential in the fight against SARS-CoV-2.

7 Apr 2020

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Metrion today announced it has contributed to two new peer-reviewed papers under the U.S. FDA CiPA (Comprehensive in vitro Proarrhythmia Assay) initiative.

From Metrion Biosciences Limited 7 Apr 2020

Therapeutics News and Research

Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Could DPP4 inhibitors help treat COVID-19?

Super-charging production of drugs for COVID-19

Molecular pathway responsible for TNBC's progression and spread identified

FDA approves first-ever treatment for patients with inoperable plexiform neurofibromas

Rockefeller and SNF announce $3 million expansion of partnership for COVID-19 research

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

Hinge Therapeutics and TUT collaborate to advance drug discovery by ion imaging

Researchers identify COVID-19 drug lead treatments

Microneedle patches for potential COVID-19 vaccines or therapeutics

Combination of rare, damaging mutations negatively affects healthspan and longevity

'Off-the-shelf' artificial cardiac patch improves heart attack recovery in rat and pig models

Philadelphia Eagles owner contributes $1 million to Penn Medicine to fight COVID-19 pandemic

Study compares health of pregnant and non-pregnant women with IBD

Australian plant that produces antibodies may help in coronavirus vaccine production

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

How do viruses mutate and jump to humans?

Research reveals a potential 'chink in the armor' of SARS-CoV-2

Brown fat cells can translate energy into heat in an unexpected way

Research suggests an avenue to treat, prevent genetic disorders in the womb

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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