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mRNA-1273 and BNT162b2 COVID-19 vaccines induce slightly different immune responses

In a recent study published in the journal Science, researchers observed differential effector functions of antibodies elicited by Pfizer’s BNT162b2 and Moderna’s messenger ribonucleic acid (mRNA)-1273 coronavirus disease 2019 (COVID-19) vaccines.

4 Apr 2022

How well does the BNT162b2 vaccine protect children and teens against Omicron?

A study published in the New England Journal of Medicine investigated the vaccine efficiency of the Pfizer BioNTech (BNT162b2) vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant in children and adolescents.

4 Apr 2022

AI helps identify areas in need of emergency aid

In a recent study published in the journal Nature, researchers developed and evaluated an approach that used machine-learning algorithms to analyze mobile phone and satellite data to estimate poverty. They aimed to optimize the ‘Novissi’ flagship emergency social assistance program in Togo, West Africa, providing subsistence cash relief to those most affected by COVID-19.

4 Apr 2022

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

While there are effective therapies to reduce the risk of heart disease by lowering low-density lipoprotein (LDL), or "bad" cholesterol, and other lipids, to date there are no approved treatments to lower lipoprotein(a), a lesser-known driver of heart disease risk.

3 Apr 2022

Extension study shows mavacamten’s efficacy and safety in treating hypertrophic cardiomyopathy

Use of mavacamten, a novel cardiac myosin inhibitor, to treat people with symptomatic obstructive hypertrophic cardiomyopathy (HCM), a condition that results in excess thickening of the heart muscle, resulted in continued benefits in patient quality of life and outcomes over an extended period of time, according to interim data from the EXPLORER-HCM extension study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Cardamonin - a natural compound found in the spice cardamom and other plants - could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells.

3 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

Personalized nutrition education at a grocery store improves adherence to DASH diet

People who received personalized nutrition education in a series of sessions conducted at their regular grocery store significantly improved their adherence to the Dietary Approaches to Stop Hypertension (DASH) diet, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Experimental siRNA therapy reduces a key driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

3 Apr 2022

Study investigates messenger ribonucleic acid-based SARS-CoV-2 vaccine efficacy against SARS-CoV-2 Omicron in Denmark

A new study assessed the efficacy of two SARS-CoV-2 vaccines against Omicron infections and disease-related hospitalization in the Denmark population.

1 Apr 2022

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

A team of international scientists has recently isolated and characterized pan-coronavirus neutralizing antibodies from individuals with pre-existing immunity against SARS-CoV-2.

1 Apr 2022

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

Researchers assessed the efficacy of TMPRSS2 against SARS-CoV-2 variants of concern Alpha, Beta, Gamma, and Delta, in mice and human lung cells.

1 Apr 2022

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

In a new study, researchers developed a whole-genome sequencing pipeline based on nanopore technology for the rapid identification of genetic variants.

1 Apr 2022

Study reveals how zinc supports immunity, suggests ways it could be used to improve health

Zinc's immune-boosting properties are well-established, but scientists haven't known exactly how it works.

1 Apr 2022

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

Faculty from the Departments of Microbiology, Medicine Genetics and Genomic Sciences, and Pathology and Molecular Cell-Based Medicine at the Icahn School of Medicine at Mount Sinai play key roles in a National Institutes of Health (NIH) program set up to provide a real-time risk assessment of variants of SARS-CoV-2, the virus that causes COVID-19. The program, called SARS-CoV-2 Assessment of Viral Evolution (SAVE) and described in a paper published March 31 in Nature, assesses how the variants might affect transmission, virulence, and resistance to both disease-induced (convalescent) and vaccine-induced immunity.

31 Mar 2022

Efficacy News and Research

mRNA-1273 and BNT162b2 COVID-19 vaccines induce slightly different immune responses

How well does the BNT162b2 vaccine protect children and teens against Omicron?

AI helps identify areas in need of emergency aid

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

Extension study shows mavacamten’s efficacy and safety in treating hypertrophic cardiomyopathy

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Personalized nutrition education at a grocery store improves adherence to DASH diet

Experimental siRNA therapy reduces a key driver of heart disease risk by up to 98%

Study investigates messenger ribonucleic acid-based SARS-CoV-2 vaccine efficacy against SARS-CoV-2 Omicron in Denmark

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

Study investigates rapid nanopore whole-genome sequencing approach for identifying genetic variants

Study reveals how zinc supports immunity, suggests ways it could be used to improve health

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

Therapeutic antibodies against filoviruses including Ebola and Marburg

Potential new approach could make Japanese encephalitis vaccine more affordable

How effective are household cleaning agents against SARS-CoV-2?

Novaplex real-time PCR assays can reliably, rapidly detect SARS-CoV-2 in patient samples

Liposomes tailored for pulmonary delivery for treating acute respiratory distress syndrome

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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