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Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Despite doctors’ concerns, pharmacists get more leeway to offer treatment with testing

When Reyna or Justin Ansley or one of their three kids feels sick and needs to be tested for strep throat or flu, there's a good chance they'll head to their local pharmacy in Hemingford or Alliance, Nebraska. Dave Randolph, the proprietor of both locations of Dave's Pharmacy, can do a rapid test, give them medicine if they need it, and send them on their way.

31 Mar 2022

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Researchers demonstrated the inhalation of an ACE2 decoy receptor, sACE22.v2.4-IgG1, increases survival and ameliorates lung injury in K18-hACE2 transgenic mice.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

A new study shows that multiple variants of this virus may coinfect the same patient, using both genomic sequencing data and computational models.

30 Mar 2022

Caffeine could be a therapeutic arsenal to alleviate some of the ADHD symptoms

Attention Deficit Hyperactivity Disorder, or ADHD, is a psychiatric pathology for which diagnosis has increased exponentially over the last 20 years.

29 Mar 2022

Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer.

29 Mar 2022

Trial shows effectiveness of new classes of dual active ingredient insecticidal nets against malaria

IVCC welcomes the publication in The Lancet of the 24-month results of an epidemiological trial in Tanzania, conducted by the London School of Hygiene and Tropical Medicine in partnership with the National Institute for Medical Research, Kilimanjaro Christian Medical University College, and the University of Ottawa, to assess the public health value of two dual active ingredient nets compared to standard LLINs containing pyrethroids only.

29 Mar 2022

Trigeminal ganglia cell atlas implicates several cell types in migraine

Headaches such as migraine are among the leading causes of morbidity worldwide, but most treatments provide only partial relief.

29 Mar 2022

Study explores the waning efficacy of SARS-CoV-2 ChAdOx1 and BNT162b2 vaccines

A new study evaluated the waning efficacy of the COVID-19 ChAdOx1 and BNT162b2 vaccines over six months following the second dose.

29 Mar 2022

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Researchers evaluated the cellular and humoral immunity following heterologous and homologous COVID-19 immunization regimens for up to five months.

29 Mar 2022

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

A new study presented the findings of the Phase 3 trial of the Nanocovax coronavirus disease 2019 (COVID-19) vaccine.

29 Mar 2022

Algal metabolites as novel drugs against viruses

A new review article published in the Journal of Biotechnology has provided information on various nutraceutical metabolites extracted from algae.

29 Mar 2022

Fourth COVID-19 vaccine dose substantially reduces mortality in the elderly

Researchers determine whether there was any reduction in the death rate in elderly COVID-19 patients following the second booster dose.

28 Mar 2022

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Adding an anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumor growth, according to a proof-of-concept study led by Cedars-Sinai Cancer investigators.

28 Mar 2022

New, potential treatment combination for patients with aggressive head and neck cancer

The current treatment of patients diagnosed with advanced or metastatic head and neck cancer (HNC) is ineffective.

28 Mar 2022

Study shows how cells use octopus-like tentacles to move around the body

With help from the best tweezers in the world a team of researchers from the University of Copenhagen has shed new light on a fundamental mechanism in all living cells that helps them explore their surroundings and even invade tissue.

28 Mar 2022

Mathematical model of SARS-CoV-2 transmission tailored to the unique situation of China

Researchers designed a dynamic mathematical model to simulate the transmission of the SARS-CoV-2 Omicron variant in China and project its associated burden on healthcare facilities, should the zero-COVID-19 policy be lifted.

28 Mar 2022

Efficacy News and Research

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Despite doctors’ concerns, pharmacists get more leeway to offer treatment with testing

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

The potential efficacy of nasal nanoparticle COVID-19 vaccines

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

Caffeine could be a therapeutic arsenal to alleviate some of the ADHD symptoms

Penn researchers generate functional CAR T cells with enhanced anti-tumor potency in 24 hours

Trial shows effectiveness of new classes of dual active ingredient insecticidal nets against malaria

Trigeminal ganglia cell atlas implicates several cell types in migraine

Study explores the waning efficacy of SARS-CoV-2 ChAdOx1 and BNT162b2 vaccines

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

Algal metabolites as novel drugs against viruses

Fourth COVID-19 vaccine dose substantially reduces mortality in the elderly

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

New, potential treatment combination for patients with aggressive head and neck cancer

Study shows how cells use octopus-like tentacles to move around the body

Mathematical model of SARS-CoV-2 transmission tailored to the unique situation of China

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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