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Multiple gene substitution in tomatoes helps improve yield, nutrient content

Cooked, fresh, sun-dried, or juiced, whichever way you prefer them, tomatoes are arguably one of the most versatile fruits on the planet--and yes, despite mainly being used in savory dishes, tomatoes really are a fruit.

2 Dec 2020

Nanomedicine's giant step into the fight against the COVID-19

A recent editorial in Nature Nanotechnology discusses the enormous feat of scientific innovation, with messenger RNA (mRNA)-based vaccines developed to deliver the gene sequence of specific SARS-CoV-2 viral proteins into host cells using nanotechnology platforms.

1 Dec 2020

Researchers uncover the role of protein in identifying common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

1 Dec 2020

SARS-CoV-2's microRNAs may have promoted its jump to humans

A new study uses machine learning to explore the small microRNAs (or miRNAs) of SARS-CoV-2 that may determine the virus's ability to successfully infect humans by altering the course of transcriptional events.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Molecular techniques explain how the Great Barrier Reef corals survived tough conditions

In a ground-breaking new study, scientists used innovative molecular techniques to explain how corals on the east coast of Australia survived previous tough conditions--enabling the Great Barrier Reef to become the vast reef it is today.

1 Dec 2020

Scientists use large-scale method to study genes associated with autism spectrum disorder

Scientists at Harvard University, the Broad Institute of MIT and Harvard, and MIT have developed a technology to investigate the function of many different genres in many different cell types at once, in a living organism.

1 Dec 2020

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

3D8, a 27-kDa recombinant antibody fragment, was found in autoimmune-prone Murphy Roths Large mice. The single-chain variable fragment (scFv) has the nucleic acid hydrolyzing activity and is shown to degrade DNA or mRNA of viruses in infected cells.

30 Nov 2020

Researchers find way for customized programming of human stem cells

Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues for drug testing and cell replacement therapies. However, the "recipes" for this conversion are often complicated and difficult to implement.

30 Nov 2020

New selective method for DNA sequencing could enable quicker diagnosis of rare diseases

Scientists at the University of Nottingham have made a major breakthrough in genome sequencing, which will enable them to search for the underlying causes of diseases in human DNA quicker than ever before.

30 Nov 2020

Study describes the role of Zmat3 in lymphoma and lung cancer development

A new study from the UPF and WEHI (the Walter and Eliza Hall Institute of Medical Research) in Melbourne, Australia, has described the role of p53 target gene Zmat3 in lymphoma and lung cancer development.

30 Nov 2020

SARS-CoV-2 launches multipronged attack against host cell protein synthesis, study finds

An interesting new study throws a flood of light on how SARS-CoV-2 accomplishes its mission to infect and replicate within host cells while evading the host immune response.

27 Nov 2020

SARS-CoV-2 spike protein shows slow but stable evolution, study finds

A new preprint published in November 2020 describes the seven different clades into which the virus has diversified.

27 Nov 2020

Researchers develop synthetic defective SARS-CoV-2 genome that inhibits viral replication

A shorter genome comprising only a part of the SARS-CoV-2's RNA genome competes with the normal virus for growth and can potentially prevent viral replication.

26 Nov 2020

Early interferon therapy may mitigate COVID-19 severity

A recent review of COVID-19 therapies explores the utility of interferons in the battle against severe COVID-19, and concludes that they deserve further development.

26 Nov 2020

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

A team of scientists from South Korea and the United States has conducted an interesting study to investigate whether mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect the severity of coronavirus disease 2019 (COVID-19). The study findings reveal that mutations in the viral spike protein and RNA polymerase complex can increase the risk of COVID-19 mortality.

25 Nov 2020

Genome News and Research

Multiple gene substitution in tomatoes helps improve yield, nutrient content

Nanomedicine's giant step into the fight against the COVID-19

Researchers uncover the role of protein in identifying common cold virus

SARS-CoV-2's microRNAs may have promoted its jump to humans

Researchers successfully edit SIV virus from genomes of non-human primates

Molecular techniques explain how the Great Barrier Reef corals survived tough conditions

Scientists use large-scale method to study genes associated with autism spectrum disorder

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

Researchers find way for customized programming of human stem cells

New selective method for DNA sequencing could enable quicker diagnosis of rare diseases

Study describes the role of Zmat3 in lymphoma and lung cancer development

SARS-CoV-2 launches multipronged attack against host cell protein synthesis, study finds

SARS-CoV-2 spike protein shows slow but stable evolution, study finds

Researchers develop synthetic defective SARS-CoV-2 genome that inhibits viral replication

Early interferon therapy may mitigate COVID-19 severity

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

Genetic risk of pre-eclampsia linked to blood pressure and BMI, study reveals

Scientists use 3D mapping techniques to unravel mystery of blood stem cells

Study sheds new light on genetic risk factors that make individuals susceptible to severe COVID-19

New insights on telomere length changes and DNA damage responses during space flight

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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