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New method can detect high levels of COVID-19 antibodies

A more efficient and much faster method to assess high levels of neutralizing antibodies to COVID-19 could point the way to better understanding and treatment of the disease, according to new published findings by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) and the University of Michigan (U-M).

23 Oct 2020

Researchers create AI system that matches tumors to best drug combinations

Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA).

23 Oct 2020

DNA vaccine-induced antibodies neutralize SARS-CoV-2

The coronavirus disease (COVID-19) is far from over as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage across the globe. With the vast spread of the virus, many countries who reported flattening the curve over the past months have reported clusters of new cases and second waves of the outbreak.

22 Oct 2020

First antiviral treatment for COVID-19 receives FDA approval

Today, the U.S. Food and Drug Administration approved the antiviral drug Veklury (remdesivir) for use in adult and pediatric patients 12 years of age and older and weighing at least 40 kilograms (about 88 pounds) for the treatment of COVID-19 requiring hospitalization.

22 Oct 2020

Aspirin use associated with reduced mortality risk in hospitalized COVID-19 patients

Hospitalized COVID-19 patients who were taking a daily low-dose aspirin to protect against cardiovascular disease had a significantly lower risk of complications and death compared to those who were not taking aspirin, according to a new study led by researchers at the University of Maryland School of Medicine.

22 Oct 2020

Robotic Trunk Support Trainer helps children with cerebral palsy to sit more stably

Cerebral palsy (CP) is the most common childhood physical disability - 2.0-3.5 per 1000 births - and children born with it have impaired development and diminished control of movement and posture.

22 Oct 2020

Metabolite of dietary soy may lower risk factor for dementia

A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia--with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health.

22 Oct 2020

Tumor DNA in spinal fluid can help track children with aggressive brain tumors

For many cancers, doctors are increasingly looking to the DNA that solid tumors shed into the blood stream to help with diagnosis and monitoring. But brain cancer has been a different story thanks to the natural blockade created by the blood-brain barrier.

22 Oct 2020

Newly developed light-sensing protein restores vision in blind mice

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy.

22 Oct 2020

Researchers receive more than $1 million NIH grants for COVID-19 pandemic-related projects

Researchers in Northern Arizona University's Center for Health Equity Research and the Southwest Health Equity Research Collaborative recently received four grants totaling more than $1 million from the National Institutes of Health for projects related to the COVID-19 pandemic.

21 Oct 2020

First COPD patient treated with RejuvenAir System in a multicenter clinical trial

Temple University Hospital has treated the first patient in a multicenter international clinical trial utilizing the RejuvenAir System for the treatment of patients suffering from moderate to severe chronic obstructive pulmonary disease with chronic bronchitis.

21 Oct 2020

Can ordinary COVID patients get the Trump treatment? It’s OK to ask

When Terry Mutter woke up with a headache and sore muscles on a recent Wednesday, the competitive weightlifter chalked it up to a hard workout.

20 Oct 2020

Study finds higher cannabis dose is associated with larger reductions in OCD compulsions

People with obsessive-compulsive disorder, or OCD, report that the severity of their symptoms was reduced by about half within four hours of smoking cannabis, according to a Washington State University study.

20 Oct 2020

Template for COVID-19 management in a rural health system

As the COVID-19 pandemic continues to challenge existing health networks, a new study published on the preprint server medRxiv in October 2020 reports on a strategy to address existing health care disparities in rural and urban areas of the USA. This should draw attention to the need for more such systems to ensure proper rural healthcare in the current and future pandemics.

20 Oct 2020

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

The COVID-19 pandemic has led to intensive scientific efforts to bring about an effective vaccine for global distribution. Many different vaccine design approaches are underway. A recent study published in the journal The Lancet Infectious Diseases in October 2020 reports a potentially successful inactivated virus vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Oct 2020

Experimental ALS drug shows potential to prolong patient survival

An experimental medication that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, has now demonstrated the potential to also prolong patient survival.

16 Oct 2020

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

The National Institutes of Health has launched an adaptive Phase 3 clinical trial to evaluate the safety and efficacy of three immune modulator drugs in hospitalized adults with COVID-19.

16 Oct 2020

Study: Combining sound and electrical stimulation of tongue can reduce tinnitus

In the largest clinical trial of its kind, researchers show that combining sound and electrical stimulation of the tongue can significantly reduce tinnitus, commonly described as "ringing in the ears." They also found that therapeutic effects can be sustained for up to 12 months post-treatment.

16 Oct 2020

MITHRAS trial investigates superiority of TMVR-induced iASD over medical therapy

The MITHRAS randomized clinical trial found that interventional closure of an iatrogenic atrial septal defect (iASD) driven by transcatheter mitral valve repair (TMVR) was not superior to conservative medical treatment with regard to the primary endpoint of change in six-minute walking distance.

16 Oct 2020

REFLECT II clinical trial evaluates safety and efficacy of cerebral embolic deflection filter

The REFLECT II randomized clinical trial evaluating the safety and efficacy of a device designed to reduce cerebral embolization and ischemic stroke, complications of transcatheter aortic valve replacement (TAVR), found that the device met the primary safety endpoint compared to historical controls but did not demonstrate superiority of the device for the primary hierarchical efficacy endpoint.

16 Oct 2020

Clinical Trial News and Research

New method can detect high levels of COVID-19 antibodies

Researchers create AI system that matches tumors to best drug combinations

DNA vaccine-induced antibodies neutralize SARS-CoV-2

First antiviral treatment for COVID-19 receives FDA approval

Aspirin use associated with reduced mortality risk in hospitalized COVID-19 patients

Robotic Trunk Support Trainer helps children with cerebral palsy to sit more stably

Metabolite of dietary soy may lower risk factor for dementia

Tumor DNA in spinal fluid can help track children with aggressive brain tumors

Newly developed light-sensing protein restores vision in blind mice

Researchers receive more than $1 million NIH grants for COVID-19 pandemic-related projects

First COPD patient treated with RejuvenAir System in a multicenter clinical trial

Can ordinary COVID patients get the Trump treatment? It’s OK to ask

Study finds higher cannabis dose is associated with larger reductions in OCD compulsions

Template for COVID-19 management in a rural health system

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

Experimental ALS drug shows potential to prolong patient survival

NIH launches adaptive Phase 3 clinical trial to test immune modulator drugs in COVID-19 patients

Study: Combining sound and electrical stimulation of tongue can reduce tinnitus

MITHRAS trial investigates superiority of TMVR-induced iASD over medical therapy

REFLECT II clinical trial evaluates safety and efficacy of cerebral embolic deflection filter

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