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How malaria drugs could play a part in treating chemotherapy-resistant head and neck cancers

In this interview, we speak to Kirill Kiselyov, Ph.D, and Umamaheswar Duvvuri, M.D, Ph.D, from the University of Pittsburgh, about their latest research into hydroxychloroquine, a drug widely used to prevent and treat malaria, as a potential treatment for head and neck cancers.

28 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

SARS-CoV-2 antibodies in breast milk remain after Holder pasteurization

Researchers study the impact of pasteurization on specific Ig concentration against SARS-CoV-2 in milk from mRNA vaccinated lactating women.

27 Mar 2022

Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

Researchers discuss the results of a clinical trial to assess the efficacy and safety of IV sarilumab for the treatment of hospitalized COVID-19 patients.

27 Mar 2022

Novel ACL reconstruction technique in younger patients garners positive results two years post-surgery

A new study by researchers at Hospital for Special Surgery in New York City presented today at the American Academy of Orthopaedic Surgeons 2022 Annual Meeting found that a novel surgical technique performed during anterior cruciate ligament (ACL) reconstruction in certain younger patients garnered positive results two years post-surgery.

27 Mar 2022

HIV patients on antiretroviral treatment with protease inhibitors may have lower COVID-19 risk

A preliminary study to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases in Lisbon, Portugal (23-26 April), suggests that people living with HIV who are on antiretroviral treatment (ART) with protease inhibitors (PI), may have a lower risk of COVID-19 infection.

27 Mar 2022

Burt's Bees research demonstrates the efficacy of natural origin skincare regimens

Burt's Bees, a pioneer in nature-based skin care, announced its latest research findings on the efficacy of natural origin skincare regimens.

25 Mar 2022

NTU-developed coating for probiotics ensures effective delivery of beneficial bacteria into the intestine

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed probiotics with a unique edible coating that ensures the beneficial bacteria successfully reach the intestine once they are ingested.

25 Mar 2022

Tablet containing cannabidiol effectively reduces pain after shoulder surgery

An orally absorbed tablet containing cannabidiol (CBD) effectively reduces pain after shoulder surgery with no safety concerns, a new study finds.

25 Mar 2022

How the timing and dose of different types of passive antibody treatments predict protection from SARS-CoV-2 infection

A new study has focussed on conducting a systematic search of the literature and aggregated data associated with randomized control trials of passive antibody therapy.

25 Mar 2022

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

A new study has focussed on screening and identification of possible SMIs of this PPI for COVID-19.

25 Mar 2022

Effectiveness of a 'test-and-treat' approach for identification and treatment of vitamin D insufficiency for prevention of COVID-19

Researchers determined the impact of vitamin D status in preventing all-cause acute respiratory infection and SARS-CoV-2 infection.

25 Mar 2022

Scientists describe use of PCR in detecting SARS-CoV-2 in paraffine-embedded tissues

Scientists compared the efficacy of the quantitative polymerase chain reaction method and immunohistochemistry in detecting SARS-CoV-2 in different human tissues.

25 Mar 2022

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

A recent study presented topologically engineered fragment crystallizable-fusion proteins and antibodies as therapeutic options for diseases like human coronaviruses infections and cancers.

25 Mar 2022

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers evaluated the neutralizing antibody titers and anti-receptor-binding domain immunoglobulin G titers in sera of kidney transplant recipients who were vaccinated against COVID-19 and treated with 300 mg dosage of Evusheld™

25 Mar 2022

Researchers characterize vaccines for infectious bronchitis virus

A new study characterized the genetic and immunological aspects of the infectious bronchitis virus (IBV) vaccines commercially used in Korea.

25 Mar 2022

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Researchers reported the efficacy of their self-developed CASCADE biosensor in naked-eye detection of SARS-CoV-2 RNA using gold nanoparticles.

25 Mar 2022

Reduced kidney function caused by antithrombotic therapy can influence bleeding events

Antithrombotic therapy is prescribed to prevent thrombotic (blood clotting inside a blood vessel) events but the treatment also increases the likelihood of experiencing a bleeding event, which can be extremely serious if it occurs in a vital organ.

25 Mar 2022

Study shows third dose of Pfizer-BioNTech vaccine against COVID-19 is both safe and effective

A research paper published in the New England Journal of Medicine has demonstrated how a third dose of Pfizer-BioNTech (BNT162b2) vaccine administered in a median period of 10.8 months after the second one bestowed 95.3% efficacy against coronavirus disease 2019 (COVID-19), in comparison with two doses of the same vaccine during a median follow-up of 2.5 months.

24 Mar 2022

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

A team of international scientists has developed an mRNA-based coronavirus disease 2019 (COVID-19) vaccine encoding the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant. The vaccine candidate has shown high efficacy in inducing neutralizing antibodies and protecting against delta infection in mice. The study is currently available on the bioRxiv* preprint server.

24 Mar 2022

Efficacy News and Research

How malaria drugs could play a part in treating chemotherapy-resistant head and neck cancers

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

SARS-CoV-2 antibodies in breast milk remain after Holder pasteurization

Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

Novel ACL reconstruction technique in younger patients garners positive results two years post-surgery

HIV patients on antiretroviral treatment with protease inhibitors may have lower COVID-19 risk

Burt's Bees research demonstrates the efficacy of natural origin skincare regimens

NTU-developed coating for probiotics ensures effective delivery of beneficial bacteria into the intestine

Tablet containing cannabidiol effectively reduces pain after shoulder surgery

How the timing and dose of different types of passive antibody treatments predict protection from SARS-CoV-2 infection

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

Effectiveness of a 'test-and-treat' approach for identification and treatment of vitamin D insufficiency for prevention of COVID-19

Scientists describe use of PCR in detecting SARS-CoV-2 in paraffine-embedded tissues

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers characterize vaccines for infectious bronchitis virus

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Reduced kidney function caused by antithrombotic therapy can influence bleeding events

Study shows third dose of Pfizer-BioNTech vaccine against COVID-19 is both safe and effective

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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