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European Commission approves Pfizer’s first oncology biosimilar

Pfizer Inc. today announced the European Commission has approved TRAZIMERA, a biosimilar to Herceptin (trastuzumab), for the treatment of human epidermal growth factor overexpressing breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

31 Jul 2018

Long-term heat therapy may increase mitochondrial function in muscles

A new study finds that long-term heat therapy may increase mitochondrial function in the muscles. The discovery could lead to new treatments for people with chronic illness or disease. The study, the first of its kind in humans - is published ahead of print in the Journal of Applied Physiology.

31 Jul 2018

Study uncovers why elderly people struggle to swallow

A new study has revealed people naturally lose muscle and function in the throat as they age, making it harder for food to move from the mouth to the space above the food pipe.

31 Jul 2018

New nano-optic endoscopes offer high-resolution imaging at extended depth of focus

The diagnosis of diseases based in internal organs often relies on biopsy samples collected from affected regions.

31 Jul 2018

Study: Brief period of inactivity can trigger diabetic symptoms in vulnerable patients

Just two weeks without much activity can have a dramatic impact on health from which it is difficult to recover, according to researchers who studied overweight older adults at risk of developing Type 2 diabetes.

31 Jul 2018

Being overweight may set the stage for heart disease later in life

Even as a young adult, being overweight may cause higher blood pressure and thicken heart muscle, setting the stage for heart disease later in life, according to new research in the American Heart Association's journal Circulation.

30 Jul 2018

Football training helps improve bone health in 55-70-year-olds with prediabetes

Football scores from all angles for untrained middle-aged and elderly women and men with prediabetes. This is the conclusion from a study carried out in the Faroe Islands by football researchers and physiologists from the Department of Sports Science and Clinical Biomechanics at the University of Southern Denmark and the University of the Faroe Islands.

28 Jul 2018

Open-source software creates powerful, accurate simulations for movement research

An open-source movement simulator that has already helped solve problems in medicine, paleontology, and animal locomotion has been expanded and improved, according to a new publication in the open-access journal PLOS Computational Biology.

27 Jul 2018

New study aims to develop nucleoside therapy as treatment for mitochondrial depletion syndromes

Hundreds of types of mitochondrial disease affect up to 38 million people worldwide, yet there are very few effective treatments, forcing patients and doctors to rely on symptom management to battle the serious and potentially fatal genetic disorder that starves the body’s cells of energy.

27 Jul 2018

LYVE-1 protein on macrophages found to be key to artery health

Arteries such as the aorta actively transport oxygenated blood, nutrients and cells throughout the body to keep our tissues functioning normally. Damage to the arteries can result in life-threatening cardiovascular diseases.

27 Jul 2018

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

Newer version of ALS drug may effectively treat inherited form of the disease

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1.

27 Jul 2018

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

An international team of scientists, including researchers from Baylor College of Medicine, has discovered mutations of gene IRF2BPL that are associated with a previously undiagnosed neurological disorder in seven unrelated individuals.

27 Jul 2018

Study helps to explain why older adults experience dysphagia

As adults age, they all experience a natural loss of muscle mass and function. A new study finds that as the loss of muscle and function in the throat occurs it becomes more difficult for efficient constriction to occur while swallowing - which leads to an increased chance of food and liquids being left over in the throat.

26 Jul 2018

Researchers find distinct microbiomes in airway, gastrointestinal systems of children with chronic cough

Different respiratory diseases associated with chronic cough create distinct microbial imbalances in the lower airways of children, according to a study led by researchers at NYU School of Medicine.

26 Jul 2018

Ciprofloxacin may disrupt normal functions of connective tissue

The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment

26 Jul 2018

Discovery of strange parasitic link to entrepreneurialism

Good news for cat lovers! A latest study has found that a parasite infestation found in cat feces could make a person an entrepreneur. Cat feces commonly contain parasite Toxoplasma gondii and its infection can often go unnoticed in most individuals. A new study has found that people who have had T. gondii infection are around 1.4 times more likely to major in business studies compared to those who were not infected.

25 Jul 2018