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Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

study evaluates senolytic CAR T-cell therapy targeting uPAR-positive cells in aged mice, showing its effectiveness in mitigating age-related metabolic dysfunction and offering a potential long-lasting treatment for aging-associated conditions.

28 Jan 2024

Embracing mindfulness to combat life’s stressors and optimize cognitive performance

Professor Andra Smith, from the School of Psychology at the Faculty of Social Sciences, has combined her research and her personal experience with mindfulness to teach the course Neuroscience of Mindfulness: Neurons to Wellness.

27 Jan 2024

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

27 Jan 2024

Research upends understanding of circadian clock in melanoma

A Ludwig Cancer Research study has found that the circadian clock - which synchronizes physiological and cellular activities with the day-night cycle and is generally thought to be tumor suppressive - in fact has a contextually variable role in cancer.

27 Jan 2024

New study of daylight vision using canine model offers critical insight into restoring cone function

In the retinas of human eyes, the cones are photoreceptor cells responsible for color vision, daylight vision, and the perception of small details.

27 Jan 2024

Immunotherapy breakthrough: Pembrolizumab extends time to recurrence in aggressive bladder cancer

Patients with muscle-invasive urothelial cancer and a high risk of recurrence after surgery may have a new treatment option.

27 Jan 2024

Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital).

27 Jan 2024

Study offers insights into who's at risk for long COVID among immunocompromised patients

Early in the pandemic, clinicians noticed that certain immunocompromised patients were experiencing persistent SARS-CoV-2 infections, some lasting weeks to months at a time.

26 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs - with the addition of an also already FDA-approved complement inhibitor - are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Study addresses knowledge gap of clinical features and outcomes of Black patients with melanoma

Researchers identified patient- and tumor-level melanoma features in black individuals.

25 Jan 2024

Mood boosters reduce inflammation in IBD by 18%, study finds

New King's College London research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood intervention.

24 Jan 2024

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness.

24 Jan 2024

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Researchers analyzed the toxicity concerns and advancements in mRNA therapeutics, focusing on their cellular toxicity, reactogenicity, and distribution, and discussed the challenges and benefits of mRNA research.

24 Jan 2024

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature Medicine.

24 Jan 2024

New study reveals key tissues involved in HIV rebound after treatment

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify that lymph nodes in the abdomen are the leading source of rebound infection after the first week of stopping antiretroviral treatment.

24 Jan 2024

Therapy News and Research

Revolutionary CAR T-cell therapy shows promise in reversing age-related metabolic dysfunction

Embracing mindfulness to combat life’s stressors and optimize cognitive performance

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

Research upends understanding of circadian clock in melanoma

New study of daylight vision using canine model offers critical insight into restoring cone function

Immunotherapy breakthrough: Pembrolizumab extends time to recurrence in aggressive bladder cancer

Prime editing takes gene therapy to the next level

Study offers insights into who's at risk for long COVID among immunocompromised patients

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Study addresses knowledge gap of clinical features and outcomes of Black patients with melanoma

Mood boosters reduce inflammation in IBD by 18%, study finds

Study shows effectiveness of gene therapy in treating congenital deafness

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

New study reveals key tissues involved in HIV rebound after treatment

Mayo Clinic unveils "secret gene" key to reversing heart failure in some patients

Functional, nonepileptic seizures linked to higher death rate than expected

T cells can be reprogrammed to fight aging

Researchers uncover a gene that causes heart defects in Down syndrome

Rice scientists identify promising new immunological pathway to treat breast cancer bone metastases

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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