Efficacy News and Research

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Flo; Much more than a period tracker

In this interview, we speak to Sonia Ponzo, the Director of Science at Flo Health, about their app and how it's revolutionizing the field of women's health.

From Flo Health 22 Mar 2022

Early treatment of COVID-19 in high-risk children and adolescents infected with the Omicron variant of SARS-CoV-2

Researchers discussed patient features, treatment-associated process measures, and outcomes associated with early monoclonal antibody and antiviral therapy in high-risk pediatric patients infected with the SARS-CoV-2 Omicron variant.

22 Mar 2022

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Researchers evaluated the importance of the Ex3Lx6L motif in SARS-CoV-2 entry into host cells mediated by the spike protein syncytium formation and membrane fusion.

22 Mar 2022

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions.

22 Mar 2022

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

A recent study posted to the bioRxiv* preprint server demonstrated the neutralizing capacity of existing SARS-CoV-2 vaccines against the severe acute respiratory coronavirus 2 (SARS-CoV-2) Omicron BA.2 and BA.1 sublineages.

22 Mar 2022

Environmental surveillance for early detection of COVID-19 outbreaks

A recent study posted to the medRxiv* preprint server investigated whether environmental samples could serve as early indicators for detecting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in large communities.

22 Mar 2022

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

The findings of a new study suggest that a ketogenic diet - which is low in carbohydrates and protein, but high in fat - helps to kill pancreatic cancer cells when combined with a triple-drug therapy developed by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

22 Mar 2022

Association between seropositivity and comorbidities after COVID-19 vaccination

In a recent study posted to the medRxiv* preprint server, researchers demonstrated that comorbidities attenuated the chance of seropositivity following coronavirus disease 2019 (COVID-19) vaccination.

22 Mar 2022

Is COVID-19 on the verge of ending?

Researchers explore the changes arising in SARS-CoV-2 over time.

21 Mar 2022

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

A research team at Colorado State University has discovered that drugs used to treat malaria are also effective at treating a pulmonary disease similar to tuberculosis.

21 Mar 2022

Factors influencing Australian mothers to vaccinate kids against COVID-19, get tested, and self-isolate

A new study investigates whether family demographic factors were associated with mothers’ willingness to vaccinate their four-year-old children.

21 Mar 2022

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

The National Institutes of Health is awarding a $3.8 million grant to John Rossmeisl, the Dr. and Mrs. Dorsey Taylor Mahin Professor of Neurology and Neurosurgery at the Virginia-Maryland College of Veterinary Medicine, and Waldemar Debinski, cancer biology professor at the Wake Forest School of Medicine.

21 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

In a new study, researchers aimed to determine if peptidyl-arginine deiminases inhibitors may be used as a novel class of host-targeting antivirals against human coronaviruses.

21 Mar 2022

Influence of vitamin D and age on first SARS-CoV-2 vaccine dose efficacy

Researchers illustrated that vitamin D status and age influence antibody response following the initial dose of coronavirus disease 2019 vaccination.

21 Mar 2022

Clinical severity of SARS-CoV-2-Omicron infection found to be lower than Delta infection

Researchers evaluated the severity of SARS-CoV-2cc infection by the Omicron variant compared to the Delta variant.

21 Mar 2022

Phase 2 trial evaluates the safety and immunogenicity of two doses of the SARS-CoV-2 vaccine MVC-COV1901 in adolescents

A recent study evaluated the safety and immunogenicity of a COVID-19 vaccine in a phase II trial.

21 Mar 2022

Safety and antibody responses to COVID-19 vaccines in an older community

Researchers evaluated the antibody responses in an older cohort following COVID-19 vaccination and compared them to a younger cohort.

21 Mar 2022

The importance of the endosomal pathway for SARS-CoV-2 entry

Researchers demonstrated that combined inhibition of cell-surface-based and endosomal pathways completely blocked SARS-CoV-2 entry into mammalian cells.

21 Mar 2022

Study unveils several natural marine products as potential agents against SARS-CoV-2

A recent study, published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy, highlighted three natural marine products as potent inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – without any apparent toxic effects for human lung cells.

21 Mar 2022

Efficacy News and Research

Flo; Much more than a period tracker

Early treatment of COVID-19 in high-risk children and adolescents infected with the Omicron variant of SARS-CoV-2

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

Environmental surveillance for early detection of COVID-19 outbreaks

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

Association between seropositivity and comorbidities after COVID-19 vaccination

Is COVID-19 on the verge of ending?

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

Factors influencing Australian mothers to vaccinate kids against COVID-19, get tested, and self-isolate

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

Influence of vitamin D and age on first SARS-CoV-2 vaccine dose efficacy

Clinical severity of SARS-CoV-2-Omicron infection found to be lower than Delta infection

Phase 2 trial evaluates the safety and immunogenicity of two doses of the SARS-CoV-2 vaccine MVC-COV1901 in adolescents

Safety and antibody responses to COVID-19 vaccines in an older community

The importance of the endosomal pathway for SARS-CoV-2 entry

Study unveils several natural marine products as potential agents against SARS-CoV-2

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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