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New tool interprets whole-exome tumor sequencing data for better cancer therapies

A University of Colorado Cancer study published today in the Journal of the American Medical Informatics Association describes a new tool that interprets the raw data of whole exome tumor sequencing and then matches the cancer's unique genetics to FDA-approved targeted treatments.

30 Mar 2016

Swedish population study helps answer lingering questions about hormone therapy safety

A Swedish population study is helping answer lingering questions about hormone therapy safety. Published online today in Menopause, the journal of The North American Menopause Society, the study shows that estrogen-only therapy carries a lower risk of blood clots than combined estrogen-progestogen therapy, but there is no significantly increased risk of clots with combination therapy when the estrogen is transdermal, and vaginal estrogen doesn't raise the risk at all.

30 Mar 2016

Smoking drastically alters oral microbiome, study finds

Smoking drastically alters the oral microbiome, the mix of roughly 600 bacterial species that live in people's mouths. This is the finding of a study led by NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center to be published online March 25 in the ISME (International Society for Microbial Ecology) Journal.

30 Mar 2016

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Scientists have devised a triple-stage "cluster bomb" system for delivering the chemotherapy drug cisplatin, via tiny nanoparticles designed to break up when they reach a tumor.

30 Mar 2016

Annual economic cost of U.S. premature births linked to air pollution reaches $4.33 billion

The annual economic cost of the nearly 16,000 premature births linked to air pollution in the United States has reached $4.33 billion, according to a report by scientists at NYU Langone Medical Center.

29 Mar 2016

New approach allows noninvasive identification of tumor mutations in lung cancer patients

Researchers at the Stanford University School of Medicine have devised a way to significantly increase the sensitivity of a technique to identify and sequence DNA from cancer cells circulating in a person's blood.

29 Mar 2016

Promising UCLA discovery could lead to new method for improving cancer treatments

A promising new discovery by UCLA scientists could lead to a new method of identifying cancer patients that express high levels of an enzyme and are more likely to respond to cancer treatments.

29 Mar 2016

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UT Southwestern Medical Center researchers have discovered a mutation that causes a rare systemic disorder known as X-linked reticulate pigmentary disorder (XLPDR) and, significantly, the unexpected cellular mechanism by which the mutation causes the disease.

29 Mar 2016

UC Berkeley biologists discover potential target for unisex contraceptives

UC Berkeley biologists have discovered the switch that triggers the power kick sperm use to penetrate and fertilize a human egg, uncovering a possible source of male infertility but also a potential target for contraceptives that work in both men and women.

26 Mar 2016

Inactivation of protein-coding gene promotes liver tissue regeneration in mammals

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) report that inactivating a certain protein-coding gene promotes liver tissue regeneration in mammals.

26 Mar 2016

IBM's World Community Grid supports TB eradication project

The University of Nottingham is launching a new study to address tuberculosis (TB), one of the world's most deadly diseases, supported by IBM's World Community Grid -- one of the most powerful and fastest virtual supercomputers on the planet.

25 Mar 2016

Personalized medicine promises better treatment options for cystic fibrosis patients

For a highly variable disease like cystic fibrosis, personalized medicine promises treatments based on individual factors, down to the molecular level. This promise is especially alluring for the treatment of children with cystic fibrosis, who are at particular risk for complications that could affect them throughout their lives.

25 Mar 2016

Air pollution can lead to premature death

People who live where there are high levels of air pollution have an increased risk of dying prematurely. Air pollution levels in Gothenburg have, however, decreased by half in the past few decades.

25 Mar 2016

UAM implements family-centered care model to provide better patient outcomes

Family presence when a child is undergoing tracheal intubation in a pediatric intensive care unit (PICU) can safely be implemented as part of a family-centered care model, reported a research team led by a University of Arkansas for Medical Sciences professor in the March 7 issue of JAMA Pediatrics.

24 Mar 2016

Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

The use of peripheral nerve blocks (PNBs) is associated with better medical and economic outcomes in patients receiving hip and knee replacement, according to research being presented at the 41st Annual Regional Anesthesiology and Acute Pain Medicine Meeting later this month.

24 Mar 2016

Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Advances in personalized medicine allow doctors to select the most promising drugs for certain types of malignant tumors.

24 Mar 2016

Cinqair (reslizumab) approved for treatment of severe asthma

The U.S. Food and Drug Administration today approved Cinqair (reslizumab) for use with other asthma medicines for the maintenance treatment of severe asthma in patients aged 18 years and older. Cinqair is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

23 Mar 2016

Research findings offer new way to differentiate, treat patients with lung cancer

Research in Manchester has identified mutations in lung cancer that is key to tumour growth, offering a new way to differentiate and treat some patients with the disease.

23 Mar 2016

SLU researchers discover compound that disrupts fibrotic process

Saint Louis University researchers have found that a type of compound that disrupts the process that causes fibrosis (scarring) in the lungs and liver also shows promise in preventing and treating fibrosis in yet another organ, the pancreas. The research was conducted in an animal model.

23 Mar 2016

Parasitic flatworm rejuvenates its skin to survive in human bloodstream

A parasitic flatworm that infects hundreds of millions of people in the developing world is able to survive in the bloodstream for decades by constantly renewing its skin - a mechanism that could inform potential new treatments against infection.

23 Mar 2016

Lungs News and Research

New tool interprets whole-exome tumor sequencing data for better cancer therapies

Swedish population study helps answer lingering questions about hormone therapy safety

Smoking drastically alters oral microbiome, study finds

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Annual economic cost of U.S. premature births linked to air pollution reaches $4.33 billion

New approach allows noninvasive identification of tumor mutations in lung cancer patients

Promising UCLA discovery could lead to new method for improving cancer treatments

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UC Berkeley biologists discover potential target for unisex contraceptives

Inactivation of protein-coding gene promotes liver tissue regeneration in mammals

IBM's World Community Grid supports TB eradication project

Personalized medicine promises better treatment options for cystic fibrosis patients

Air pollution can lead to premature death

UAM implements family-centered care model to provide better patient outcomes

Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Cinqair (reslizumab) approved for treatment of severe asthma

Research findings offer new way to differentiate, treat patients with lung cancer

SLU researchers discover compound that disrupts fibrotic process

Parasitic flatworm rejuvenates its skin to survive in human bloodstream

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